Date published: 2026-7-21

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SIRT 抗体和相关产品

圣克鲁斯生物技术公司的 SIRT 单克隆抗体种类繁多,用于研究 sirtuins,这是一个参与细胞调节的蛋白质家族,包括新陈代谢、衰老和应激反应。SIRT 单克隆抗体与多种研究技术兼容,包括 Western 印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组织化学 (IHCP)、流式细胞术 (FCM) 和酶联免疫吸附试验 (ELISA)。Sirtuins 可使蛋白质去乙酰化,从而促进 DNA 修复、基因表达和细胞凋亡等细胞过程,维持细胞的平衡和寿命。sirtuins 参与新陈代谢调节并与老年相关疾病有关,这使它们成为基础研究和应用研究的重要目标。了解 sirtuin 的功能可以为肥胖、糖尿病和神经退行性疾病等疾病的治疗策略提供见解。对 sirtuin 活性的研究不断揭示影响细胞健康和衰老过程的新途径和新机制。研究 sirtuin 的调控有助于科学家更好地了解它们在疾病预防和治疗开发中的作用。圣克鲁斯生物技术公司的 SIRT 单克隆抗体使全球研究人员能够推进对细胞调控和老年相关疾病的科学理解。

関連項目

SIRT 抗体

Empty Table Header产品名称目录亚型抗原决定簇应用 Species应用排名

SIRT1 抗体 (B-7)

sc-74465mouse IgG1 κ448-747 (h)WB, IP, IF, IHC(P), ELISAm, r, h
175
(35)

SIRT1 抗体 (B-10)

sc-74504mouse IgG2b κ448-747 (h)WB, IP, IF, IHC(P), ELISAh
99
(43)

SIRT1 抗体 (33.36)

sc-135792mouse IgG1 κ(h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(2)

SIRT2 抗体 (A-5)

sc-28298mouse IgG1 κ1-95 (h)WB, IP, IF, IHC(P), ELISAm, r, h
31
(21)

SIRT3 抗体 (F-10)

sc-365175mouse IgG2b κ251-290 (h)WB, IP, IF, ELISAm, r, h
69
(30)

SIRT4 抗体 (95.1)

sc-135797mouse IgG2a κ241-255 (h)WB, IP, ELISAh
12
(2)

SIRT5 抗体 (G-2)

sc-271635mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(12)

SIRT6 抗体 (2G1H1)

sc-517196mouse IgG1 κ141-250 (h)WB, IP, IF, ELISAh
16
(7)

SIRT6 抗体 (6C9-D10-D3)

sc-517556mouse IgG(h)WB, IF, IHC(P)m, r, h
4
(0)

SIRT7 抗体 (C-3)

sc-365344mouse IgG1 κ1-105 (h)WB, IP, IF, ELISAm, r, h
32
(5)

SIRT siRNA, shRNA 质粒和 shRNA 慢病毒颗粒基因沉默产品

Empty Table Header产品名称目录Species应用 标记物应用排名

SIRT1 siRNA (h)

sc-40986hGene SilencingN/A
124
(1)

SIRT1 shRNA 质粒 (h)

sc-40986-SHhGene SilencingPuromycin
124
(1)

SIRT1 shRNA (h) 慢病毒颗粒

sc-40986-VhGene SilencingPuromycin
124
(1)

SIRT1 siRNA (m)

sc-40987mGene SilencingN/A
55
(0)

SIRT1 shRNA 质粒 (m)

sc-40987-SHmGene SilencingPuromycin
55
(0)

SIRT1 shRNA (m) 慢病毒颗粒

sc-40987-VmGene SilencingPuromycin
55
(0)

SIRT1 siRNA (r)

sc-108043rGene SilencingN/A
45
(0)

SIRT1 shRNA 质粒 (r)

sc-108043-SHrGene SilencingPuromycin
45
(0)

SIRT1 shRNA (r) 慢病毒颗粒

sc-108043-VrGene SilencingPuromycin
45
(0)

SIRT2 siRNA (h)

sc-40988hGene SilencingN/A
11
(0)

SIRT2 shRNA 质粒 (h)

sc-40988-SHhGene SilencingPuromycin
11
(0)

SIRT2 shRNA (h) 慢病毒颗粒

sc-40988-VhGene SilencingPuromycin
11
(0)

SIRT2 siRNA (m)

sc-40989mGene SilencingN/A
1
(0)

SIRT2 shRNA 质粒 (m)

sc-40989-SHmGene SilencingPuromycin
1
(0)

SIRT2 shRNA (m) 慢病毒颗粒

sc-40989-VmGene SilencingPuromycin
1
(0)

SIRT3 siRNA (h)

sc-61555hGene SilencingN/A
44
(1)

SIRT3 shRNA 质粒 (h)

sc-61555-SHhGene SilencingPuromycin
44
(1)

SIRT3 shRNA (h) 慢病毒颗粒

sc-61555-VhGene SilencingPuromycin
44
(1)

SIRT3 siRNA (m)

sc-61556mGene SilencingN/A
35
(0)

SIRT3 shRNA 质粒 (m)

sc-61556-SHmGene SilencingPuromycin
35
(0)

SIRT3 shRNA (m) 慢病毒颗粒

sc-61556-VmGene SilencingPuromycin
35
(0)

SIRT3-GFP shRNA (h) 慢病毒颗粒

sc-61555-VGhGene SilencingPuromycin
44
(1)

SIRT4 siRNA (h)

sc-63024hGene SilencingN/A
5
(0)

SIRT4 shRNA 质粒 (h)

sc-63024-SHhGene SilencingPuromycin
5
(0)

SIRT4 shRNA (h) 慢病毒颗粒

sc-63024-VhGene SilencingPuromycin
5
(0)

SIRT4 siRNA (m)

sc-63025mGene SilencingN/A
1
(0)

SIRT4 shRNA 质粒 (m)

sc-63025-SHmGene SilencingPuromycin
1
(0)

SIRT4 shRNA (m) 慢病毒颗粒

sc-63025-VmGene SilencingPuromycin
1
(0)

SIRT5 siRNA (h)

sc-63026hGene SilencingN/A
2
(0)

SIRT5 shRNA 质粒 (h)

sc-63026-SHhGene SilencingPuromycin
2
(0)

SIRT5 shRNA (h) 慢病毒颗粒

sc-63026-VhGene SilencingPuromycin
2
(0)

SIRT5 siRNA (m)

sc-63027mGene SilencingN/A
2
(0)

SIRT5 shRNA 质粒 (m)

sc-63027-SHmGene SilencingPuromycin
2
(0)

SIRT5 shRNA (m) 慢病毒颗粒

sc-63027-VmGene SilencingPuromycin
2
(0)

SIRT6 siRNA (h)

sc-63028hGene SilencingN/A
13
(0)

SIRT6 shRNA 质粒 (h)

sc-63028-SHhGene SilencingPuromycin
13
(0)

SIRT6 shRNA (h) 慢病毒颗粒

sc-63028-VhGene SilencingPuromycin
13
(0)

SIRT6 siRNA (m)

sc-63029mGene SilencingN/A
4
(0)

SIRT6 shRNA 质粒 (m)

sc-63029-SHmGene SilencingPuromycin
4
(0)

SIRT6 shRNA (m) 慢病毒颗粒

sc-63029-VmGene SilencingPuromycin
4
(0)

SIRT7 siRNA (h)

sc-63030hGene SilencingN/A
11
(0)

SIRT7 shRNA 质粒 (h)

sc-63030-SHhGene SilencingPuromycin
11
(0)

SIRT7 shRNA (h) 慢病毒颗粒

sc-63030-VhGene SilencingPuromycin
11
(0)

SIRT7 siRNA (m)

sc-63031mGene SilencingN/A
4
(0)

SIRT7 shRNA 质粒 (m)

sc-63031-SHmGene SilencingPuromycin
4
(0)

SIRT7 shRNA (m) 慢病毒颗粒

sc-63031-VmGene SilencingPuromycin
4
(0)

SIRT 转染裂解液

Empty Table Header产品名称目录Species对照抗体应用排名

SIRT1 (h): 293T Lysate

sc-113797h0
(0)

SIRT CRISPR 基因敲除 (KO) 和 HDR 质粒

Empty Table Header产品名称目录应用 Species应用排名

SIRT1 CRISPR/Cas9 KO质粒 (h)

sc-400085Gene Knockouth0
(2)

SIRT1 HDR 质粒 (h)

sc-400085-HDRHomology Directed Repairh0
(2)

SIRT1 CRISPR/Cas9 KO质粒 (m2)

sc-430046-KO-2Gene Knockoutm0
(0)

SIRT1 HDR 质粒 (m2)

sc-430046-HDR-2Homology Directed Repairm0
(0)

SIRT2 CRISPR/Cas9 KO质粒 (h2)

sc-400590-KO-2Gene Knockouth0
(1)

SIRT2 HDR 质粒 (h2)

sc-400590-HDR-2Homology Directed Repairh0
(1)

SIRT2 CRISPR/Cas9 KO质粒 (m)

sc-425703Gene Knockoutm0
(0)

SIRT3 HDR 质粒 (h2)

sc-400675-HDR-2Homology Directed Repairh0
(0)

SIRT3 CRISPR/Cas9 KO质粒 (m2)

sc-425704-KO-2Gene Knockoutm0
(0)

SIRT3 HDR 质粒 (m2)

sc-425704-HDR-2Homology Directed Repairm0
(0)

SIRT3 CRISPR/Cas9 KO质粒 (r)

sc-437315Gene Knockoutr0
(0)

SIRT3 HDR 质粒 (r)

sc-437315-HDRHomology Directed Repairr0
(0)

SIRT4 CRISPR/Cas9 KO质粒 (h)

sc-401187Gene Knockouth0
(0)

SIRT4 HDR 质粒 (h)

sc-401187-HDRHomology Directed Repairh0
(0)

SIRT4 CRISPR/Cas9 KO质粒 (r)

sc-437316Gene Knockoutr0
(0)

SIRT5 CRISPR/Cas9 KO质粒 (h)

sc-416994Gene Knockouth0
(0)

SIRT5 HDR 质粒 (h)

sc-416994-HDRHomology Directed Repairh0
(0)

SIRT5 CRISPR/Cas9 KO质粒 (m)

sc-427028Gene Knockoutm0
(0)

SIRT5 HDR 质粒 (m)

sc-427028-HDRHomology Directed Repairm0
(0)

SIRT5 CRISPR/Cas9 KO质粒 (r)

sc-437317Gene Knockoutr0
(0)

SIRT5 HDR 质粒 (r)

sc-437317-HDRHomology Directed Repairr0
(0)

SIRT6 CRISPR/Cas9 KO质粒 (h)

sc-412216Gene Knockouth0
(1)

SIRT6 HDR 质粒 (h)

sc-412216-HDRHomology Directed Repairh0
(1)

SIRT6 CRISPR/Cas9 KO质粒 (m2)

sc-424467-KO-2Gene Knockoutm0
(0)

SIRT6 HDR 质粒 (m2)

sc-424467-HDR-2Homology Directed Repairm0
(0)

SIRT7 CRISPR/Cas9 KO质粒 (h)

sc-401401Gene Knockouth0
(0)

SIRT7 HDR 质粒 (h)

sc-401401-HDRHomology Directed Repairh0
(0)

SIRT7 CRISPR/Cas9 KO质粒 (m)

sc-431608Gene Knockoutm0
(0)

SIRT7 HDR 质粒 (m)

sc-431608-HDRHomology Directed Repairm0
(0)

SIRT CRISPR 双尼克酶质粒

Empty Table Header产品名称目录应用 Species应用排名

SIRT1双切口酶质粒(h)

sc-400085-NICGene Knockouth0
(0)

SIRT1双切口酶质粒(h2)

sc-400085-NIC-2Gene Knockouth0
(0)

SIRT1双切口酶质粒(m)

sc-430046-NICGene Knockoutm0
(0)

SIRT1双切口酶质粒(m2)

sc-430046-NIC-2Gene Knockoutm0
(0)

SIRT2双切口酶质粒(h)

sc-400590-NICGene Knockouth0
(0)

SIRT2双切口酶质粒(h2)

sc-400590-NIC-2Gene Knockouth0
(0)

SIRT2双切口酶质粒(m)

sc-425703-NICGene Knockoutm0
(0)

SIRT3双切口酶质粒(h)

sc-400675-NICGene Knockouth0
(0)

SIRT3双切口酶质粒(h2)

sc-400675-NIC-2Gene Knockouth0
(0)

SIRT3双切口酶质粒(m)

sc-425704-NICGene Knockoutm0
(0)

SIRT3双切口酶质粒(m2)

sc-425704-NIC-2Gene Knockoutm0
(0)

SIRT3双切口酶质粒(r)

sc-437315-NICGene Knockoutr0
(0)

SIRT3双切口酶质粒(r2)

sc-437315-NIC-2Gene Knockoutr0
(0)

SIRT4双切口酶质粒(h)

sc-401187-NICGene Knockouth0
(0)

SIRT4双切口酶质粒(h2)

sc-401187-NIC-2Gene Knockouth0
(0)

SIRT4双切口酶质粒(r)

sc-437316-NICGene Knockoutr0
(0)

SIRT4双切口酶质粒(r2)

sc-437316-NIC-2Gene Knockoutr0
(0)

SIRT5双切口酶质粒(h)

sc-416994-NICGene Knockouth0
(0)

SIRT5双切口酶质粒(h2)

sc-416994-NIC-2Gene Knockouth0
(0)

SIRT5双切口酶质粒(m)

sc-427028-NICGene Knockoutm0
(0)

SIRT5双切口酶质粒(m2)

sc-427028-NIC-2Gene Knockoutm0
(0)

SIRT5双切口酶质粒(r)

sc-437317-NICGene Knockoutr0
(0)

SIRT5双切口酶质粒(r2)

sc-437317-NIC-2Gene Knockoutr0
(0)

SIRT6双切口酶质粒(h)

sc-412216-NICGene Knockouth0
(0)

SIRT6双切口酶质粒(h2)

sc-412216-NIC-2Gene Knockouth0
(0)

SIRT6双切口酶质粒(m)

sc-424467-NICGene Knockoutm0
(0)

SIRT6双切口酶质粒(m2)

sc-424467-NIC-2Gene Knockoutm0
(0)

SIRT7双切口酶质粒(m)

sc-431608-NICGene Knockoutm0
(0)

SIRT CRISPR 激活质粒和慢病毒颗粒

Empty Table Header产品名称目录应用 Species应用排名

SIRT1CRISPR激活质粒(h)

sc-400085-ACTGene Activationh0
(0)

SIRT1CRISPR激活质粒(h2)

sc-400085-ACT-2Gene Activationh0
(0)

SIRT1慢病毒激活颗粒(h)

sc-400085-LACGene Activationh0
(0)

SIRT1CRISPR激活质粒(m)

sc-430046-ACTGene Activationm0
(0)

SIRT1CRISPR激活质粒(m2)

sc-430046-ACT-2Gene Activationm0
(0)

SIRT1慢病毒激活颗粒(m)

sc-430046-LACGene Activationm0
(0)

SIRT3CRISPR激活质粒(h)

sc-400675-ACTGene Activationh0
(0)

SIRT3CRISPR激活质粒(h2)

sc-400675-ACT-2Gene Activationh0
(0)

SIRT3CRISPR激活质粒(m)

sc-425704-ACTGene Activationm0
(0)

SIRT3慢病毒激活颗粒(m)

sc-425704-LACGene Activationm0
(0)

SIRT4CRISPR激活质粒(h)

sc-401187-ACTGene Activationh0
(0)

SIRT5CRISPR激活质粒(h)

sc-416994-ACTGene Activationh0
(0)

SIRT5CRISPR激活质粒(h2)

sc-416994-ACT-2Gene Activationh0
(0)

SIRT6CRISPR激活质粒(m)

sc-424467-ACTGene Activationm0
(0)

SIRT6CRISPR激活质粒(m2)

sc-424467-ACT-2Gene Activationm0
(0)

SIRT7CRISPR激活质粒(h)

sc-401401-ACTGene Activationh0
(0)

SIRT7CRISPR激活质粒(h2)

sc-401401-ACT-2Gene Activationh0
(0)