Date published: 2025-10-10

021-6093-6350

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ZAR1L 抑制因子

he class of chemical compounds known as ZAR1L inhibitors belongs to a distinctive category within the realm of small-molecule inhibitors, characterized by their specific interaction with the Zygote Arrest 1-like protein (ZAR1L). ZAR1L is a molecular player associated with crucial cellular processes, particularly those related to reproductive biology and embryonic development. The inhibitors within this class exert their effects by selectively modulating the activity of ZAR1L, a protein involved in the regulation of oocyte maturation and early embryonic development. The chemical structures of ZAR1L inhibitors are meticulously designed to bind to specific regions of the ZAR1L protein, thereby altering its conformation and impeding its normal function. This targeted inhibition has the potential to unravel novel insights into the intricacies of reproductive biology, as ZAR1L is known to be intricately involved in the coordination of meiosis and the subsequent fusion of male and female gametes.

ZAR1L inhibitors signifies a significant stride in the field of chemical biology, contributing to the elucidation of intricate cellular pathways. Researchers are keenly exploring the biochemical and biophysical aspects of ZAR1L inhibition to decipher the molecular mechanisms underpinning its role in reproduction. As the understanding of ZAR1L function advances, these inhibitors may serve as invaluable tools for probing cellular processes with high precision. The rational design and synthesis of ZAR1L inhibitors exemplify the integration of chemical and biological knowledge, fostering a nuanced comprehension of the molecular events governing early embryogenesis and reproductive physiology.

関連項目

Items 1 to 10 of 11 total

展示:

产品名称CAS #产品编号数量价格应用排名

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
¥925.00
¥1692.00
¥4377.00
113
(4)

激酶抑制剂可破坏各种信号通路,可能会影响参与细胞周期控制的 ZAR1L 等蛋白质。

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
¥1365.00
¥4423.00
148
(1)

PI3K抑制剂,可改变下游信号传导,可能影响与生长发育相关的蛋白质,包括ZAR1L。

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
¥745.00
¥2471.00
¥4705.00
97
(3)

另一种可调节信号通路的 PI3K 抑制剂,可能会对涉及 ZAR1L 的细胞过程产生影响。

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
¥440.00
¥1015.00
212
(2)

一种 MEK 抑制剂,可破坏 MAPK/ERK 通路,对 ZAR1L 等可能与细胞生长信号有关的蛋白质产生潜在影响。

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
¥301.00
¥1128.00
257
(3)

一种 JNK 抑制剂,可调节应激反应途径,对 ZAR1L 等可能与这些途径有关的蛋白质产生潜在影响。

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
¥993.00
¥3858.00
284
(5)

p38 MAPK 抑制剂,可改变炎症反应和应激信号传导,并可能影响 ZAR1L 相关通路。

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
¥699.00
¥1749.00
¥3610.00
233
(4)

mTOR 抑制剂,可影响细胞生长和增殖,从而间接影响 ZAR1L 的活性或表达。

Nutlin-3

548472-68-0sc-45061
sc-45061A
sc-45061B
1 mg
5 mg
25 mg
¥632.00
¥2392.00
¥8619.00
24
(1)

它能破坏 p53 和 MDM2 之间的相互作用,从而导致细胞周期进程的改变,并可能影响 ZAR1L 的相关过程。

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
¥1681.00
¥5303.00
¥6995.00
¥13527.00
¥23579.00
33
(3)

组蛋白去乙酰化酶抑制剂,可改变基因表达谱,从而可能影响 ZAR1L 在细胞中的作用。

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
¥1061.00
¥3937.00
114
(2)

肌浆/内质网 Ca2+ ATP 酶(SERCA)的抑制剂,可导致细胞钙信号改变,从而可能影响 ZAR1L。