Date published: 2025-9-7

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TCL-1B2 抑制因子

TCL-1B2 inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the TCL-1B2 protein, a member of the TCL1 family, which is known for its involvement in cellular signaling pathways that regulate growth, proliferation, and survival. TCL-1B2 is thought to function by interacting with key signaling molecules, particularly those involved in the PI3K/AKT pathway, a crucial pathway that governs cell metabolism, survival, and growth in response to extracellular signals. By inhibiting TCL-1B2, these compounds can disrupt its interactions with other proteins, leading to alterations in the PI3K pathway and other interconnected signaling networks. This disruption has a significant impact on cellular processes such as the cell cycle, metabolism, and signal transduction.

The study of TCL-1B2 inhibitors provides valuable insights into the role of TCL-1B2 in maintaining cellular homeostasis and regulating intracellular communication. Researchers use these inhibitors to examine how blocking TCL-1B2 affects key signaling events that contribute to cellular responses like growth and differentiation. Through the inhibition of TCL-1B2, scientists can also explore the unique role this protein plays within the broader TCL1 protein family, offering a more refined understanding of how specific members of this family contribute to signaling regulation. These inhibitors are important tools for uncovering the molecular dynamics of the PI3K/AKT pathway and its role in regulating diverse cellular functions, allowing for a better understanding of how cells balance growth signals and maintain metabolic stability. In essence, TCL-1B2 inhibitors are instrumental in dissecting the complexity of intracellular signaling networks and the protein interactions that sustain cellular function and structure.

関連項目

Items 1 to 10 of 11 total

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产品名称CAS #产品编号数量价格应用排名

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
¥745.00
¥2471.00
¥4705.00
97
(3)

沃特曼宁是一种甾体代谢物,是磷酸肌酸 3- 激酶(PI3K)的强效抑制剂,可能会通过影响 PI3K/AKT 信号通路来降低 TCL1B 的活性。

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
¥1365.00
¥4423.00
148
(1)

LY294002 是一种合成分子,可抑制 PI3K,从而降低 AKT 磷酸化,并可能减少 TCL1B 介导的信号传导。

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
¥699.00
¥1749.00
¥3610.00
233
(4)

雷帕霉素是一种免疫抑制剂,可抑制 PI3K/AKT 通路的下游靶点 mTOR,从而可能影响与 TCL1B 相关的细胞增殖。

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
¥733.00
¥3012.00
257
(3)

SP600125 是一种 c-Jun N 端激酶(JNK)的蒽吡唑啉酮抑制剂,可通过改变 AP-1 转录因子相关的信号转导来改变 TCL1B 的活性。

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
¥993.00
¥3858.00
284
(5)

SB203580 是一种吡啶基咪唑衍生物,可选择性抑制 p38 MAPK,从而调节 TCL1B 发挥作用的细胞环境。

Palbociclib

571190-30-2sc-507366
50 mg
¥3554.00
(0)

Palbociclib 是细胞周期蛋白依赖性激酶 4/6 (CDK4/6) 的选择性抑制剂,可能会影响细胞周期的进展,从而间接影响 TCL1B 的活性。

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
¥440.00
¥1015.00
212
(2)

PD98059 是一种抑制 MEK 的合成化合物,可能会导致 ERK 激活减少,并间接影响 TCL1B 信号通路。

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
¥530.00
¥1636.00
51
(1)

达沙替尼是一种多激酶抑制剂,对SRC家族激酶具有活性,可能会影响与TCL1B通路交叉的信号级联。

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
¥1038.00
¥2516.00
30
(1)

PP2 是 Src 家族酪氨酸激酶的选择性抑制剂,可改变影响 TCL1B 相关过程的下游信号。

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
¥632.00
¥2933.00
¥4693.00
129
(3)

索拉非尼(Sorafenib)是一种针对多种受体的激酶抑制剂,可能会影响与 TCL1B 相关的信号通路。