Date published: 2025-9-8

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Von Hippel Lindau/VHL 抗体 (D-7): sc-55506

4.3(7)
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说明书
  • Von Hippel Lindau/VHL抗体(D-7)是小鼠单克隆IgG1 κ, 在5篇文献中引用,规格为200 µg/ml
  • 针对氨基酸1-181的抗体,代表全长VHL (von Hippel-Lindau tumor suppressor protein)(von Hippel-Lindau肿瘤抑制蛋白),源自mouse
  • 抗-Von Hippel Lindau/VHL 抗体 (D-7) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 VHL
  • 抗Von Hippel Lindau/VHL抗体(D-7)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Von Hippel Lindau/VHL (D-7): sc-55506免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG1 BP-HRP 是 Von Hippel Lindau/VHL 抗体 (D-7) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Von Hippel Lindau/VHL 抗体 (D-7) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

VHL 抗体 (D-7) 是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、免疫组织化学和酶联免疫吸附试验 (ELISA) 等应用检测小鼠、大鼠和人类样本中的 VHL。抗 VHL 抗体 (D-7) 有非共轭型和多种共轭型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 共轭物。von Hippel-Lindau (VHL) 蛋白通过靶向降解缺氧诱导因子 (HIF),从而控制参与血管生成和红细胞生成的基因表达,在调节细胞对缺氧的反应方面起着至关重要的作用。这一功能可维持细胞平衡并防止肿瘤发生,因为 HIFs 的失调会导致血管过度形成并引发各种癌症。VHL 基因发生种系突变的个体易患多种肿瘤,包括肾细胞癌、血管母细胞瘤和嗜铬细胞瘤,这凸显了 VHL 在抑制肿瘤方面的重要性。包括 Elongin A、B 和 C 在内的 Elongin (SIII) 复合物是 VHL 的一个关键功能靶点,因为 VHL 与调节亚基结合可抑制转录活性。不同的 VHL 异构体是由交替剪接的转录本变体产生的,在不同物种中表现出不同的分子量,突出了这种肿瘤抑制因子在癌症生物学中的复杂性和重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

Von Hippel Lindau/VHL 抗体 (D-7)

sc-55506
200 µg/ml
RMB2377.00

Von Hippel Lindau/VHL (D-7): m-IgG1 BP-HRP 套装

sc-531645
200 µg Ab; 20 µg BP
RMB2662.00

Von Hippel Lindau/VHL 抗体 (D-7) AC

sc-55506 AC
500 µg/ml, 25% agarose
RMB3129.00

Von Hippel Lindau/VHL 抗体 (D-7) HRP

sc-55506 HRP
200 µg/ml
RMB2377.00

Von Hippel Lindau/VHL 抗体 (D-7) FITC

sc-55506 FITC
200 µg/ml
RMB2482.00

Von Hippel Lindau/VHL 抗体 (D-7) PE

sc-55506 PE
200 µg/ml
RMB2580.00

Von Hippel Lindau/VHL 抗体 (D-7) Alexa Fluor® 488

sc-55506 AF488
200 µg/ml
RMB2685.00

Von Hippel Lindau/VHL 抗体 (D-7) Alexa Fluor® 546

sc-55506 AF546
200 µg/ml
RMB2685.00

Von Hippel Lindau/VHL 抗体 (D-7) Alexa Fluor® 594

sc-55506 AF594
200 µg/ml
RMB2685.00

Von Hippel Lindau/VHL 抗体 (D-7) Alexa Fluor® 647

sc-55506 AF647
200 µg/ml
RMB2685.00

Von Hippel Lindau/VHL 抗体 (D-7) Alexa Fluor® 680

sc-55506 AF680
200 µg/ml
RMB2685.00

Von Hippel Lindau/VHL 抗体 (D-7) Alexa Fluor® 790

sc-55506 AF790
200 µg/ml
RMB2685.00

Would it be possible to buy a small test aliquote of this antibody? VHL Antikörper (D-7): sc-55506 ? I would liket tu test in on my WB and Histological samples from mouse cells. Thank you very much in advance!

Asked by: Liudmyla
Thank you for your question. We currently advertise the smallest quantity available for purchase of this antibody, or 200 ug in 1 mL. Please contact our Technical Service Department for more information on how to receive a free 10 ug sample of this monoclonal antibody with your next antibody purchase.
Answered by: Technical Support
Date published: 2020-03-09

Can VHL (D-7): sc-55506 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: DefinitelyNotMatt
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, VHL (D-7): sc-55506 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 3 out of 5 by from Good ab for WB1:500 for 20ug sample. Signal was weak but detectable.
Date published: 2017-07-24
Rated 3 out of 5 by from GoodIt is weak but I get a clean band at correct size.
Date published: 2017-06-20
Rated 4 out of 5 by from Good antibody for immunoprecipitationImmunoprecipitation was done successfully with this antibody. The WB was done with it at 1:100 dilution.
Date published: 2017-06-03
Rated 5 out of 5 by from Good productI used it to do western blot, It have signal in mouse testis, Reliable!
Date published: 2017-02-12
Rated 5 out of 5 by from Produced great immunoperoxidase membraneProduced great immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human kidney tissue. -SCBT QC
Date published: 2015-05-02
Rated 5 out of 5 by from Strong bands present at correct MW in WesternStrong bands present at correct MW in Western blot analysis of VHL expression in mouse testis, mouse brain and mouse lung tissue extracts and RAW 264.7 whole cell lysate. -SCBT QC
Date published: 2015-02-05
Rated 5 out of 5 by from WB: cleanWB: clean, clear band present in F9 whole cell lysate. -SCBT QC
Date published: 2015-02-04
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Von Hippel Lindau/VHL 抗体 (D-7) is rated 4.3 out of 5 by 7.
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