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FGF-2 抗体 (A-1): sc-271847

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说明书
  • FGF-2抗体(A-1)是小鼠单克隆IgG2a κ, 在7篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的FGF-2的内部区域内的氨基酸35-67之间
  • 抗-FGF-2 抗体 (A-1) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 precursor and mature FGF-2; 也和以下物种反应,包括: 和 equine, bovine and porcine
  • 抗FGF-2抗体(A-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取FGF-2 (A-1): sc-271847免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP是FGF-2 Antibody (A-1) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与FGF-2 Antibody (A-1) 搭配使用(请参阅下面的订购信息)。

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関連項目

FGF-2抗体(A-1)是一种IgG2aκ小鼠单克隆FGF-2抗体(也称为FGF2抗体),可通过WB、IP、IF和ELISA检测来自小鼠、大鼠和人类的FGF-2前体和成熟体。FGF-2抗体(A-1)有非偶联抗FGF-2抗体形式,以及多种偶联形式的抗FGF-2抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。成纤维细胞生长因子-1(FGF-1),也称为酸性FGF,以及成纤维细胞生长因子-2(FGF-2),也称为碱性FGF,是刺激间充质、上皮和神经外胚层起源细胞增殖的生长因子家族成员。FGF家族的其他成员包括癌基因FGF-3(Int2)和FGF-4(hst/Kaposi)、FGF-5、FGF-6、FGF-7(KGF)、FGF-8(AIGF)、FGF-9(GAF)和FGF-10-FGF-23。FGF家族的成员共享30-55%的氨基酸序列同一性和相似的基因结构,并且当在转染的细胞中过表达时能够转化培养细胞。FGF的细胞受体是第二个多基因家族的成员,包括四个酪氨酸激酶,分别命名为Flg(FGFR-1)、Bek(FGFR-L)、TKF和FGFR-3。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

FGF-2 抗体 (A-1) 参考文献:

  1. TIMP-2 破坏了 FGF-2 诱导的下游信号通路。  |  Seo, DW., et al. 2008. Microvasc Res. 76: 145-51. PMID: 18721821
  2. 变性神经元释放的 FGF-2 可通过 FGFR3-ERK 信号通路发挥小胶质细胞诱导的神经保护作用。  |  Noda, M., et al. 2014. J Neuroinflammation. 11: 76. PMID: 24735639
  3. 组织工程骨膜中FGF-2和BMP-2的受控释放可促进大鼠的骨修复。  |  Yin, J., et al. 2018. Biomed Mater. 13: 025001. PMID: 29313523
  4. 内皮FGF-2-FGFR1-PDGF-BB和血管周FGF-2-FGFR2-PDGFRβ信号通路在肿瘤血管重塑中具有双重作用。  |  Hosaka, K., et al. 2018. Cell Discov. 4: 3. PMID: 29423271
  5. FGF-2通过JNK和PI3K途径抑制肾细胞连接蛋白的表达。  |  Kato, T., et al. 2018. FEBS Open Bio. 8: 836-842. PMID: 29744297
  6. 海马中的 FGF-2 信号激活有助于对葛根素的行为和细胞反应。  |  Cheng, J., et al. 2019. Biochem Pharmacol. 168: 91-99. PMID: 31251937
  7. 核壳微球以不同的释放模式递送FGF-2和BMP-2,促进骨骼再生。  |  Wang, S., et al. 2015. J Mater Chem B. 3: 1907-1920. PMID: 32262263
  8. FGF-2的释放以及含有小FGF-2聚合物颗粒的4-META/MMA基粘合树脂的粘结/物理性质。  |  Tsuboi, R., et al. 2020. Dent Mater. 36: 1586-1594. PMID: 33019973
  9. 开发用于骨再生的载有FGF-2的电纺水性聚氨酯纤维膜。  |  Zhang, C., et al. 2021. Regen Biomater. 8: rbaa046. PMID: 33732492
  10. 快速上颌扩张(RME)后腭缝中释放的VEGF和FGF-2。  |  Stuani, AS., et al. 2021. Braz Dent J. 32: 98-103. PMID: 33914010

订购信息

产品名称产品编号规格价格数量收藏夹

FGF-2 抗体 (A-1)

sc-271847
200 µg/ml
RMB2377.00

FGF-2 (A-1): m-IgG Fc BP-HRP 套装

sc-525830
200 µg Ab; 10 µg BP
RMB2662.00

FGF-2 抗体 (A-1) AC

sc-271847 AC
500 µg/ml, 25% agarose
RMB3129.00

FGF-2 抗体 (A-1) HRP

sc-271847 HRP
200 µg/ml
RMB2377.00

FGF-2 抗体 (A-1) FITC

sc-271847 FITC
200 µg/ml
RMB2482.00

FGF-2 抗体 (A-1) PE

sc-271847 PE
200 µg/ml
RMB2580.00

FGF-2 抗体 (A-1) Alexa Fluor® 488

sc-271847 AF488
200 µg/ml
RMB2685.00

FGF-2 抗体 (A-1) Alexa Fluor® 546

sc-271847 AF546
200 µg/ml
RMB2685.00

FGF-2 抗体 (A-1) Alexa Fluor® 594

sc-271847 AF594
200 µg/ml
RMB2685.00

FGF-2 抗体 (A-1) Alexa Fluor® 647

sc-271847 AF647
200 µg/ml
RMB2685.00

FGF-2 抗体 (A-1) Alexa Fluor® 680

sc-271847 AF680
200 µg/ml
RMB2685.00

FGF-2 抗体 (A-1) Alexa Fluor® 790

sc-271847 AF790
200 µg/ml
RMB2685.00

FGF-2 (A-1) 中和勝肽

sc-271847 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-271847 P appropriate for?

Asked by: cjMara
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_30, h_9CST
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Rated 5 out of 5 by from Detected recombinant rat FGF-2I tried this antibody out to detect rat FGF-2. I tested it by running it in a Western blot against recombinant rat FGF-2. This antibody could detect both reduced and non reduced recombinant rat FGF-2.
Date published: 2018-11-14
Rated 5 out of 5 by from Great antibody for ElisaI got this Ab as a free trial size for Elisa based protein-protein binding. this Ab works well with high sensitivity and specificity for Elisa. Unfortunately, the protein binding site and antibody recognition site are too close, therefore once protein-protein interacted, Ab can't bind to detect.
Date published: 2017-11-29
Rated 5 out of 5 by from Great band size at expected MW when usingGreat band size at expected MW when using this antibody against human recombinant FGF-2. -SCBT QC
Date published: 2014-12-20
Rated 5 out of 5 by from Good Western blot data of human recombinant FGFGood Western blot data of human recombinant FGF-2. -SCBT QC
Date published: 2014-12-20
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FGF-2 抗体 (A-1) is rated 5.0 out of 5 by 4.
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