Cyr61 抑制因子
Cyr61 is a secreted heparin binding protein, encoded by a growth factor-inducible immediate-early gene, that associates with the extracellular matrix and connective tissue. Biochemicals that inhibit Cyr61 have many applications in biochemical and physiological research. Click on the product name to view detailed information such as the chemical structure and specific chemical properties for each of our Cyr61 Inhibitors. In stock Cyr61 Inhibitors are available for immediate shipping.
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| 产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
雷帕霉素是一种mTOR抑制剂，可以下调Cyr61的表达。在某些情况下，mTOR信号可以诱导Cyr61的表达。通过阻断mTOR，雷帕霉素可以间接抑制Cyr61及其下游信号通路，从而抑制细胞生长、迁移和血管生成。通过抑制mTOR来靶向Cyr61可能与Cyr61在组织重塑和免疫反应中发挥重要作用的疾病有关。 | ||||||
LY2109761 | 700874-71-1 | sc-396262 sc-396262A | 1 mg 5 mg | $87.00 $270.00 | 9 | |
LY2109761是一种TGF-β I型受体（ALK5）的选择性抑制剂，可阻断TGF-β信号诱导Cyr61。通过干扰TGF-β信号，LY2109761可间接下调Cyr61及其对细胞增殖、迁移和ECM重塑的下游效应。通过抑制TGF-β来靶向Cyr61，可能对纤维化疾病、癌症转移和组织修复具有治疗意义，因为Cyr61在这些疾病中起着重要作用。 | ||||||