Date published: 2026-10-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

TRAF2 抗体 (F-4): sc-137048

5.0(5)
寫評論提問
说明书
  • TRAF2抗体(F-4)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫human物种的TRAF2的氨基酸1-249
  • 推荐用于 mouse, rat 和 human 来源的TRAF2 WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 TRAF2 (F-2): sc-136999,可查看有标记的 TRAF2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是TRAF2 Antibody (F-4) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与TRAF2 Antibody (F-4) 打包提供(请参阅下面的订购信息)。
Gene Editing Promo Banner

快捷链接

関連項目

肿瘤坏死因子(TNF)激活的细胞信号传导主要通过TNF受体1(TNF-R1)介导,在较小程度上通过TNF-R2介导。两种TNF受体都是不断扩大的TNF受体超家族的成员,该家族包括FAS抗原和CD40。通过鉴定两种相关蛋白TRAF1和TRAF2(分别为TNF受体相关因子1和2),为理解TNF受体介导的信号传导提供了潜在的见解。这两种蛋白都能形成异二聚体复合物,并与TNF-R2的细胞质结构域结合。该蛋白家族的第三个成员,又被称为CD40 bp、CRAF1、LAP1或TRAF3,已被鉴定并显示与CD40的细胞质结构域结合。TRAF3的特定区域与TRAF1和TRAF2区域之间的相似性定义了一个"TRAF-C"结构域,该结构域对于CD40结合和同二聚化是必要且充分的。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TRAF2 抗体 (F-4) 参考文献:

  1. TRAF2和TRAF5信号传导的生理作用和机制。  |  Au, PY. and Yeh, WC. 2007. Adv Exp Med Biol. 597: 32-47. PMID: 17633015
  2. RIPK1抑制TRAF2依赖性肝癌通路。  |  Schneider, AT., et al. 2017. Cancer Cell. 31: 94-109. PMID: 28017612
  3. TRAF2是前列腺癌患者的重要预后生物标志物。  |  Wei, B., et al. 2017. Med Sci Monit. 23: 4192-4204. PMID: 28855498
  4. TRAF2 在顺铂诱导的 p53 介导的细胞凋亡中的促凋亡功能  |  Tsuchida, M., et al. 2020. J Toxicol Sci. 45: 219-226. PMID: 32238696
  5. 鱼类 TRAF2 促进对 RGNNV 感染的先天性免疫反应  |  Li, C., et al. 2020. Fish Shellfish Immunol. 102: 108-116. PMID: 32311458
  6. SMYD2介导的TRAF2甲基化促进炎症性疾病中的NF-κB信号通路  |  Wu, W., et al. 2021. Clin Transl Med. 11: e591. PMID: 34841684
  7. SNHG15通过介导中风引起的免疫抑制中的TRAF2泛素化,成为炎症的负调控因子。  |  Sun, H., et al. 2022. J Neuroinflammation. 19: 1. PMID: 34980176
  8. 尼罗罗非鱼中 TRAF2 的特征:表达谱和降低 NF-κB 途径的作用。  |  Hu, H., et al. 2022. Fish Shellfish Immunol. 122: 13-20. PMID: 35051565
  9. TRAF2是一种先天免疫传感器,可相互调节线粒体自噬和炎症,以维持心肌细胞稳态。  |  Ma, X., et al. 2022. JACC Basic Transl Sci. 7: 223-243. PMID: 35411325
  10. 抑制内质网应激可改善慢性缺血性海马损伤,抑制IRE1α/TRAF2/ASK1/JNK依赖性凋亡。  |  Kang, K., et al. 2024. Inflammation. 47: 1479-1490. PMID: 38401021

订购信息

产品名称产品编号规格价格数量收藏夹

TRAF2 抗体 (F-4)

sc-137048
200 µg/ml
CNY2422.00

TRAF2 (F-4): m-IgG Fc BP-HRP 套装

sc-537395
200 µg Ab; 10 µg BP
CNY2715.00

TRAF2 (F-4): m-IgGκ BP-HRP 套装

sc-534649
200 µg Ab; 40 µg BP
CNY2715.00

TRAF2 (F-4): m-IgG1 BP-HRP 套装

sc-545172
200 µg Ab; 20 µg BP
CNY2715.00

What is the recommended fixation method for immunofluorescence staining with TRAF2 (F-4): sc-137048 monoclonal antibody?

Asked by: Dr Ninau Qelp
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-25
  • y_2026, m_10, d_19, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_137048, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 8ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by CJ from ClearClear, specific band in WB in KNRK whole cell lysate. -SCBT QC
Date published: 2015-05-16
Rated 5 out of 5 by FL from ClearClear, specific band in WB in mouse TRAF2 transfected 293T whole cell lysate. -SCBT QC
Date published: 2015-02-26
Rated 5 out of 5 by SS from Worked well in WB in human TRAF2 transfectedWorked well in WB in human TRAF2 transfected 293T and Jurkat whole cell lysates. -SCBT QC
Date published: 2015-02-19
Rated 5 out of 5 by QZ from Publishable data for use in IP and WB inPublishable data for use in IP and WB in rat islets. -SCBT Publication Review
Date published: 2015-01-06
Rated 5 out of 5 by TS from Beautiful immunoperoxidase cytoplasmic stainingBeautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human skeletal muscle tissue. -SCBT QC
Date published: 2013-10-07
  • y_2026, m_10, d_19, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_137048, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
TRAF2 抗体 (F-4) is rated 5.0 out of 5 by 5.
  • y_2026, m_10, d_19, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_137048, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 8ms
  • REVIEWS, PRODUCT