Date published: 2025-9-6
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Stat1 Antibody (C-111) - Western Blotting - Image 394982
Stat1 抗体 (C-111) HRP: sc-417 HRP. 对 IMR-32 (A), SK-MEL-24 (B), SK-MEL-28 (C), MCF7 (D) 和 HUV-EC-C (E) 全细胞裂解液中 Stat1 的表达进行直接 Western 印迹分析.
Stat1 抗体 (C-111) HRP: sc-417 HRP. 对 IMR-32 (A), SK-MEL-24 (B), SK-MEL-28 (C), MCF7 (D) 和 HUV-EC-C (E) 全细胞裂解液中 Stat1 的表达进行直接 Western 印迹分析.

Stat1 抗体 (C-111): sc-417

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寫評論提問

说明书
  • Stat1抗体(C-111)是小鼠单克隆IgG1 κ, 在143篇文献中引用，规格为200 µg/ml
  • human Stat1 613-739的氨基酸之间的表位图谱
  • 抗-Stat1 抗体 (C-111) 推荐用于 WB, IP 和 IF，检测mouse, rat 和human 来源的 Stat1
  • 抗Stat1抗体（C-111）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-417 X, 200 µg/0.1 ml)
  • 关于如何获取Stat1 (C-111): sc-417的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是Stat1 Antibody (C-111) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Stat1 Antibody (C-111) 打包提供（请参阅下面的订购信息）。

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相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

额外Stat抗体，包括Stat1, Stat2, Stat3, Stat4, Stat5和Stat6

Stat1抗体（C-111）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）和免疫荧光（IF）检测小鼠、大鼠和人源的Stat1蛋白。Stat1 (C-111) 抗体有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶、藻红蛋白、异硫氰酸荧光素和多种 Alexa Fluor® 结合物。 Stat1 蛋白在细胞对细胞因子（尤其是干扰素）的反应中起着关键作用，而细胞因子对免疫反应和抗病毒防御至关重要。当受到干扰素和生长因子等配体的激活时，Stat1蛋白会发生酪氨酸磷酸化，从而与Stat2蛋白形成异二聚体。Stat2蛋白是ISGF3转录因子复合物的一部分，可调节免疫反应相关基因的表达。Stat1蛋白有助于协调细胞对病原体和压力信号的反应，因此这一功能对于免疫系统的正常运作至关重要。Stat1 单克隆抗体（C-111）是研究人员研究免疫反应的复杂信号传导途径以及 Stat 蛋白在各种生物过程中的作用时的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Stat1 抗体 (C-111) 参考文献:

  1. MicroRNA-145 靶向结肠癌细胞中的 YES 和 STAT1。  |  Gregersen, LH., et al. 2010. PLoS One. 5: e8836. PMID: 20098684
  2. 信号转导和激活转录1（STAT1）功能增益突变与散播性球虫病和组织胞浆菌病  |  Sampaio, EP., et al. 2013. J Allergy Clin Immunol. 131: 1624-34. PMID: 23541320
  3. 在癌症和胰岛素抵抗疾病中靶向 STAT1。  |  Meng, C., et al. 2017. Curr Protein Pept Sci. 18: 181-188. PMID: 27855602
  4. STAT1 的线性泛素化调节控制着抗病毒干扰素信号传导。  |  Zuo, Y., et al. 2020. Nat Commun. 11: 1146. PMID: 32123171
  5. STAT1 和 STAT3 信号的氧化还原调控  |  Butturini, E., et al. 2020. Int J Mol Sci. 21: PMID: 32987855
  6. STAT1 及其在控制病毒感染中的关键作用。  |  Tolomeo, M., et al. 2022. Int J Mol Sci. 23: PMID: 35456913
  7. 细胞质 TGM2 通过抑制 TRIM21 介导的 STAT1 泛素化/降解（GTP 结合依赖性模式）促进胃癌的恶性进展。  |  Zhang, L., et al. 2023. Cancer Commun (Lond). 43: 123-149. PMID: 36353796
  8. STAT1功能缺失和功能增益种系突变导致的先天性免疫错误  |  Asano, T., et al. 2023. Clin Exp Immunol. 212: 96-106. PMID: 36420581
  9. 失调的 IFN-γ 信号在 STAT1 功能增益综合征中促进自身免疫。  |  Largent, AD., et al. 2023. Sci Transl Med. 15: eade7028. PMID: 37406138
  10. STAT1 缺乏是脊柱关节炎中幼稚 CD4+ T 细胞促炎印记的基础。  |  Cherqaoui, B., et al. 2023. Front Immunol. 14: 1227281. PMID: 37920469

订购信息

产品名称产品编号规格价格数量收藏夹

Stat1 抗体 (C-111)

sc-417
200 µg/ml
RMB2377.00

Stat1 (C-111): m-IgG Fc BP-HRP 套装

sc-528108
200 µg Ab; 10 µg BP
RMB2662.00

Stat1 (C-111): m-IgGκ BP-HRP 套装

sc-520406
200 µg Ab, 40 µg BP
RMB2662.00

Stat1 (C-111): m-IgG1 BP-HRP 套装

sc-542763
200 µg Ab; 20 µg BP
RMB2662.00

Stat1 抗体 (C-111) X

sc-417 X
200 µg/0.1 ml
RMB2377.00

Stat1 抗体 (C-111) AC

sc-417 AC
500 µg/ml, 25% agarose
RMB3129.00

Stat1 抗体 (C-111) HRP

sc-417 HRP
200 µg/ml
RMB2377.00

Stat1 抗体 (C-111) FITC

sc-417 FITC
200 µg/ml
RMB2482.00

Stat1 抗体 (C-111) PE

sc-417 PE
200 µg/ml
RMB2580.00

Stat1 抗体 (C-111) Alexa Fluor® 488

sc-417 AF488
200 µg/ml
RMB2685.00

Stat1 抗体 (C-111) Alexa Fluor® 546

sc-417 AF546
200 µg/ml
RMB2685.00

Stat1 抗体 (C-111) Alexa Fluor® 594

sc-417 AF594
200 µg/ml
RMB2685.00

Stat1 抗体 (C-111) Alexa Fluor® 647

sc-417 AF647
200 µg/ml
RMB2685.00

Stat1 抗体 (C-111) Alexa Fluor® 680

sc-417 AF680
200 µg/ml
RMB2685.00

Stat1 抗体 (C-111) Alexa Fluor® 790

sc-417 AF790
200 µg/ml
RMB2685.00

Hi, are we able to order Santa Cruz antibodies and ship to Australia? I have looked at the local distributor's website (Bio-Strategy) but could not find the products I was looking for: sc-417 X and sc-464 X. Thank you

Asked by: ajknights
Thank you for your question. Our local distributor Bio-Strategy should be able to provide you with a quote for the TransCruz version of each of these antibodies (sc-417 X and sc-464 X). Please contact them as they may just not list the X products on their website. We may be able to sell direct, but your institution would need to facilitate all import procedures. Please contact our Customer Care for more information.
Answered by: Technical Support
Date published: 2019-02-23

I am in the process of placing an order for STAT1ap91 (C-111) sc-417. could you please tell me what secondary antibody you would recommend. I will use it for western blot. thank you for your support.

Asked by: Allen shahin
Thank you for your question. We recommend using our m-IgGκ BP-HRP: sc-516102 for secondary detection. You can find the full list of our secondary binding proteins by following the link below: https://www.scbt.com/scbt/browse/Secondary-Antibodies/_/N-1hoaxk4
Answered by: SCBT Heidelberg Support
Date published: 2018-12-29

When should the TransCruz reagent sc-417 X be used instead of the standard form sc-417?

Asked by: jenniferc
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support 5
Date published: 2017-01-20
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Rated 5 out of 5 by from Detectó correctamenteWestern blot: La dilución probada fue de 1:1000 y 1:2000 con 20 ug de proteína de celulas CRFK, y en ambos detectó correctamente una banda aprox 90 kDa. IF: Se probó en la dilución 1:100, el resultado no fue concluyente, aunque se observó señal citoplásmica y nuclear en células CRFK.
Date published: 2024-04-01
Rated 5 out of 5 by from Ottima recensioneHo richiesto la small size qualche settimana fa e lo abbiamo usato su estratti totali di cellule SiHa e C4I e funziona bene. Il segnale, una banda di 91 kDa, è presente nelle SiHa e nelle C4I
Date published: 2023-06-26
Rated 5 out of 5 by from Very goodThis antibody works well in western blot of whole cell extracts prepared from several human cell lines.
Date published: 2021-05-31
Rated 4 out of 5 by from Buon funzionamentoHo comprato questo anticorpo cinque settimane fa e funziona bene
Date published: 2021-02-12
Rated 5 out of 5 by from goodgood antibody, use Stat1 and pStat1 antibody, we got the bands which we want!
Date published: 2018-02-14
Rated 4 out of 5 by from GoodI got this antibody sample last month, and it worked well at first 3 times.
Date published: 2018-01-22
Rated 3 out of 5 by from WB效果一般做的WB，试用的全加进去了，条带效果不是那么清晰，还有点脏，可能是自己操作的原因，但是同时做的其干净
Date published: 2017-12-16
Rated 5 out of 5 by from GoodThank you for your question.This product is excellent.
Date published: 2017-06-08
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Stat1 抗体 (C-111) is rated 4.7 out of 5 by 18.
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