Date published: 2025-9-7
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RNF168 Antibody (B-11) - Western Blotting - Image 32386
RNF168 抗体 (B-11): sc-101125. 对 HeLa 全细胞裂解液中 RNF168 的表达进行 Western 印迹分析.
RNF168 Antibody (B-11) - Western Blotting - Image 32386
RNF168 抗体 (B-11): sc-101125. 对 HeLa 全细胞裂解液中 RNF168 的表达进行 Western 印迹分析.
RNF168 Antibody (B-11) - Western Blotting - Image 34486
RNF168 抗体 (B-11): sc-101125. Hep G2 全细胞裂解液中 RNF168 表达的 Western 印迹分析.
RNF168 Antibody (B-11) - Immunofluorescence - Image 35805
RNF168 抗体 (B-11): sc-101125. 免疫荧光染色多聚甲醛固定的 Hep G2 细胞, 显示核定位.
RNF168 抗体 (B-11): sc-101125. 对 HeLa 全细胞裂解液中 RNF168 的表达进行 Western 印迹分析.

RNF168 抗体 (B-11): sc-101125

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寫評論提問

说明书
  • RNF168 抗体 B-11 是小鼠单克隆 IgG2b κ，RNF168抗体, 在15篇文献中引用，规格为100 µg/ml
  • 针对部分重组蛋白，其氨基酸序列在RNF168的human起源的462-572范围内
  • 推荐用于 mouse, rat 和 human 来源的RNF168 WB, IP, IF 和 ELISA检测
  • 关于如何获取RNF168 (B-11): sc-101125的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前，我们还没有完成RNF168 抗体 (B-11)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 RNF 抗体 包括 RNF11, RNF123, RNF126, RNF141, RNF152, RNF167, RNF168, RNF181, RNF20和RNF213

RNF168抗体（B-11）是一种IgG2b κ小鼠单克隆RNF168抗体（也称为RNF168抗体），可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的RNF168蛋白。RNF168抗体（B-11）既可以是非偶联的抗RNF168抗体，也可以是多种偶联形式的抗RNF168抗体。RING型锌指基序存在于许多病毒和真核蛋白质中，由一个能够结合两个锌原子的保守半胱氨酸丰富结构域组成。包含这种保守结构域的蛋白质通常参与蛋白质降解的泛素化途径。RNF168（RING finger protein 168）是一种包含571个氨基酸的蛋白质，含有一个RING型锌指。通过其RING型锌指，RNF168可能在转录调控和蛋白质降解事件中发挥作用。编码RNF168的基因定位于人类3号染色体，该染色体包含1100多个基因，包括一个趋化因子受体（CKR）基因簇和多种人类癌症相关基因位点。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RNF168 抗体 (B-11) 参考文献:

  1. RING 指介导泛素结合酶（E2）依赖性泛素化。  |  Lorick, KL., et al. 1999. Proc Natl Acad Sci U S A. 96: 11364-9. PMID: 10500182
  2. 人类 3 号和 21 号染色体进化的分子细胞遗传学剖析。  |  Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
  3. [人类第 3 号染色体热点上的新肿瘤抑制基因：新的鉴定方法]。  |  Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
  4. 灵长类进化过程中人类 3 号染色体的可塑性。  |  Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
  5. 人类信号通路的功能蛋白质组学图谱。  |  Colland, F., et al. 2004. Genome Res. 14: 1324-32. PMID: 15231748
  6. 人类 3p21.3 的进化可塑区与 '消除测试 '确定的肿瘤断裂点相吻合。  |  Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
  7. rabex-5 泛素结合结构域的晶体结构揭示了与泛素相互作用的两种模式。  |  Penengo, L., et al. 2006. Cell. 124: 1183-95. PMID: 16499958
  8. RNF168 可能通过稳定 STAT1 促进食管癌的增殖和侵袭。  |  Yu, N., et al. 2019. J Cell Mol Med. 23: 1553-1561. PMID: 30506884
  9. RNF168 在 BRCA1/2 基因缺陷的肿瘤中调节 R 环解析和基因组稳定性。  |  Patel, PS., et al. 2021. J Clin Invest. 131: PMID: 33529165
  10. COL4A家族：胃癌的潜在预后生物标志物和治疗靶点。  |  Lee, SO., et al. 2023. J Biol Chem. 299: 105043. PMID: 37451480
  11. 小鼠附件蛋白V基因组结构包括内源性逆转录病毒。  |  Feng, LL., et al. 2024. Proc Natl Acad Sci U S A. 121: e2322972121. PMID: 38968116
  12. RING 手指结构域：序列结构家族的最新实例。  |  Borden, KL. and Freemont, PS. 1996. Curr Opin Struct Biol. 6: 395-401. PMID: 8804826

订购信息

产品名称产品编号规格价格数量收藏夹

RNF168 抗体 (B-11)

sc-101125
100 µg/ml
RMB2504.00

if the  sc-101125  could be used in CHIP experiment

Asked by: ksinx
Thank you for your question. We have not tested this antibody, RNF168 (B-11): sc-101125, in ChIP, and we are not aware of any papers citing this antibody for ChIP at this time. The antibody has been cited for use in WB, IP and IF. Unfortunately, we do not offer any alternative antibodies against RNF168 that we know have been validated for ChIP. In the future, you can search for product citations by application on our website using the link below. https://www.scbt.com/scbt/misc/citationSearch.jsp
Answered by: Technical Support
Date published: 2020-04-17

What is the total volume provided of RNF168 (B-11):sc-101125 monoclonal antibody?

Asked by: jenni
Thank you for your question. This antibody is provided as 100 µg in 1 ml total volume of PBS with < 0.1% sodium azide and 0.1% gelatin.
Answered by: Technical Support 4
Date published: 2017-01-13

Can RNF168 (B-11): sc-101125 monoclonal antibody be used for detection of RNF168 of monkey origin?

Asked by: jenni
Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
Answered by: Technical Support 4
Date published: 2017-01-13
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Rated 1 out of 5 by from Didn't work on WBWe used it ai 1:100 in BSA but we couldn't detect it at 55 kDa.
Date published: 2020-10-13
Rated 1 out of 5 by from Does not work for IP!The statement that it is suitable for IP is fake. I tried several times with no success.
Date published: 2018-11-30
Rated 1 out of 5 by from not good for WB, high bandgroundsThis antibody is not good for WB. The protein is about 70KD ,why the bands on the 55KD in your instructions?
Date published: 2017-07-25
Rated 5 out of 5 by from Excellent antibodythe antibody work well in WB with clear bands. Excellent!
Date published: 2017-03-15
Rated 5 out of 5 by from worked for my WBThis antibody worked for my WB. Good antibody with less background
Date published: 2017-02-09
Rated 5 out of 5 by from OutstandingGreat IF staining and western blot results; nice product
Date published: 2017-01-23
Rated 5 out of 5 by from Good for IFThis RNF168 antibody shows good staining in IF staining.
Date published: 2017-01-12
Rated 5 out of 5 by from Clear band detected in WB in Hep G2 wholeClear band detected in WB in Hep G2 whole cell lysate. -SCBT QC
Date published: 2015-06-09
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RNF168抗体 (B-11) is rated 4.0 out of 5 by 12.
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