Date published: 2025-9-7

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Notch1 抗体 (8G10): sc-32756

5.0(2)
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说明书
  • Notch1 Antibody (8G10) is a Syrian hamster monoclonal IgG provided at 200 µg/ml
  • 针对Notch 1的mouse来源的残留物1299-1492(EGF重复33至LNG重复1的区域)
  • 推荐用于 mouse 和 rat 来源的Notch 1 WB, IP 和 IF检测
  • 看 Notch1 (A-8): sc-376403,可查看有标记的 Notch1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Notch1 抗体 (8G10)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

Notch 1 抗体(8G10)是一种仓鼠单克隆 IgG 抗体,旨在通过蛋白质印迹(WB)、免疫沉淀(IP)和免疫荧光(IF)应用在小鼠和大鼠样本中识别 Notch1(也称为神经源性位点缺口同源蛋白 1 或 LIN-12)。抗Notch1抗体(8G10)靶向Notch1蛋白的表位,即1299-1492残基(EGF重复序列33至LIN重复序列1),确保精确检测。Notch1是一种位于细胞膜上的单通道跨膜受体,在细胞命运决定、分化以及发育信号通路中发挥关键作用。当与配体(如Jagged1和Delta)结合时,Notch1会经历蛋白水解,释放出细胞内结构域,该结构域会转移到细胞核中,以调节基因表达。Notch1在细胞中的战略性定位对于细胞间通信和维持细胞稳态至关重要。Notch1信号传导失调与多种癌症和发育障碍有关,这凸显了Notch1在正常生理和疾病中的重要性。Notch1 单克隆抗体(8G10)有非结合型以及多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)以及各种 Alexa Fluor® 结合物,可满足不同的实验需求。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Notch1 抗体 (8G10)

sc-32756
200 µg/ml
RMB2377.00

Are there any issues with using sc-32756: Notch 1 (8G10) mouse monoclonal primary antibody on mouse samples?

Asked by: cjMara
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-32756 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 5 out of 5 by from In house western blot analysis of full lengthIn house western blot analysis of full length Notch 1 expression shows faint band in F9 cell lysates, but strong singular bands in LADMAC and MM-142 whole cell lysates. -SCBT QC
Date published: 2015-04-20
Rated 5 out of 5 by from Published results of immunoprecipitationPublished results of immunoprecipitation of Notch 1 from ST2 cells and HEK293T cells. -SCBT Publication Review
Date published: 2015-03-27
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Notch1 抗体 (8G10) is rated 5.0 out of 5 by 2.
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