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Integrin β2/ITGB2/CD18 抗体 (C71/16): sc-65874

5.0(2)
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说明书
  • Integrin β2/ITGB2/CD18 抗体 C71/16 是大鼠单克隆 IgG2a,提供 200 µg/ml
  • 针对从mouse来源的BW5147细胞中纯化的细胞膜蛋白
  • 推荐用于 mouse 来源的Integrin β2 WB 和 IP检测
  • 看 Integrin β2/ITGB2/CD18 (CTB104): sc-8420,可查看有标记的 Integrin β2/ITGB2/CD18 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Integrin β2/ITGB2/CD18 抗体 (C71/16)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    Integrin β2抗体(C71/16)是一种大鼠单克隆IgG2a抗体,可通过免疫印迹(WB)和免疫沉淀(IP)等应用检测小鼠样本中的Integrin β2。Integrin β2 (C71/16) 抗体是针对小鼠 BW5147 细胞纯化的细胞膜蛋白制备的。整合素β2(C71/16)单克隆抗体是整合素家族的重要组成部分,整合素家族由介导细胞粘附和信号传导的异二聚体受体组成。抗整合素 β2 抗体(C71/16)主要位于细胞表面,在连接细胞外基质和细胞骨架、促进细胞内外环境交流方面发挥着重要作用。Integrin β2(C71/16)单克隆抗体的正确定位对包括迁移、增殖和存活在内的各种细胞过程都至关重要,因为这种蛋白能让细胞对周围环境做出有效反应。抗整合素β2 抗体(C71/16)与几种关键蛋白相互作用,如 ICAMs(细胞间粘附分子),它对白细胞粘附和免疫反应非常重要。整合素 β2与这些蛋白形成复合物,在维持细胞相互作用和协调免疫功能方面具有重要意义。整合素β2会发生糖基化等翻译后修饰,这对其正确折叠、稳定性以及与细胞外配体和细胞内信号伙伴的功能性相互作用至关重要,从而确保免疫细胞的有效粘附和迁移。抗内含蛋白 β2 抗体 (C71/16) 使研究人员能够深入了解细胞粘附和信号传导途径的动态,有助于更好地理解各种生理和病理过程。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Integrin β2/ITGB2/CD18 抗体 (C71/16)

    sc-65874
    200 µg/ml
    RMB2377.00

    some of antibodies for ITGb2 are able to work with non-reduced lysates. Does this antibody work with reduced lysates? How about your WB data in this antibody? Did you use reduced or non-reduced cell lysates?

    Asked by: Yusuke
    Thank you for your question. This antibody, sc-65874, has been tested under reducing and denaturing conditions only, we have not tested it on non-reduced samples. All in house data is on reduced and denatured lysates. Please contact Technical Service by phone, (800)-457-3801 option 2, email <[email protected]>, or by live chat directly on our website, www.scbt.com if you have any further questions.
    Answered by: Tech Service
    Date published: 2018-11-30

    I am using Integrin β2 (C71/16): sc-65874 antibody for immunoprecipitation, how much antibody should I use?

    Asked by: Cweed
    Thank you for your question. We recommend using 1–10 µl (i.e., 0.2–2 µg) of antibody with 1 ml of cell lysate. However, optimal antibody concentration should be determined by titration. Please find our full immunoprecipitation protocol here: https://www.scbt.com/scbt/resources/protocols/immunoprecipitation-western-blots
    Answered by: Technical Support
    Date published: 2017-03-24
    • y_2025, m_8, d_30, h_9CST
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    Rated 5 out of 5 by from Western blot of Integrin 2 in mouse PBLWestern blot of Integrin 2 in mouse PBL whole cell lysate showed strong signal. -SCBT QC
    Date published: 2015-02-04
    Rated 5 out of 5 by from Western blot detected Integrin 2 in TKWestern blot detected Integrin 2 in TK-1 and CTLL-2 whole cell lysates. -SCBT QC
    Date published: 2013-03-14
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    Integrin β2/ITGB2/CD18 抗体 (C71/16) is rated 5.0 out of 5 by 2.
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