Date published: 2025-9-6

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Integrin α7/ITGA7 抗体 (E-2): sc-515716

5.0(1)
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说明书
  • Integrin α7/ITGA7 抗体 E-2 是小鼠单克隆 IgG1 κ,Integrin α7/ITGA7抗体, 在5篇文献中引用,规格为200 µg/ml
  • 抗原表位位于human来源Integrin α7胞外域的878-917氨基酸之间
  • Integrin α7/ITGA7 抗体 (E-2) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 precursor and mature heavy chain Integrin α7
  • 抗Integrin α7/ITGA7抗体(E-2)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 另提供生物素偶联抗体,可用于WB、IHC(P)和ELISA实验
  • 关于如何获取Integrin α7/ITGA7 (E-2): sc-515716免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 Integrin α7/ITGA7 抗体 (E-2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Integrin α7/ITGA7 抗体 (E-2) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Integrin α7/ITGA7 抗体 (E-2) 参考文献:

  1. 分析前列腺癌、肝癌、多形性胶质母细胞瘤和骨髓肉瘤中整合素 alpha7 的突变。  |  Ren, B., et al. 2007. J Natl Cancer Inst. 99: 868-80. PMID: 17551147
  2. 整合素α7能与金属蛋白酶组织抑制剂3结合,从而抑制前列腺癌细胞的生长。  |  Tan, LZ., et al. 2013. Am J Pathol. 183: 831-40. PMID: 23830872
  3. S100P 与整合素 α7 相互作用,增加了肺癌中癌细胞的迁移和侵袭。  |  Hsu, YL., et al. 2015. Oncotarget. 6: 29585-98. PMID: 26320193
  4. 整合素α7亚基的缺失不会加重层粘连蛋白α2链缺失小鼠的表型。  |  Gawlik, KI. and Durbeej, M. 2015. Sci Rep. 5: 13916. PMID: 26355035
  5. 整合素α7是食道鳞状细胞癌中一种功能性癌症干细胞表面标记物。  |  Ming, XY., et al. 2016. Nat Commun. 7: 13568. PMID: 27924820
  6. 哮喘患者体内整合素α7的表达增加,抑制整合素α7可降低气道平滑肌细胞中Kras蛋白的丰度。  |  Teoh, CM., et al. 2019. Sci Rep. 9: 9892. PMID: 31289310
  7. 整合素α7过度表达与透明细胞肾细胞癌患者病理分级升高、T分期增加、TNM分期晚期以及生存率降低有关:一项回顾性研究。  |  Chen, Y., et al. 2020. J Clin Lab Anal. 34: e23034. PMID: 31713264
  8. 整合素α7的过表达与直肠癌患者的晚期病情和预后不良有关。  |  Huang, J., et al. 2018. Int J Clin Exp Pathol. 11: 4630-4636. PMID: 31949862
  9. 血管生成因子 AGGF1 通过与血管平滑肌细胞上的整合素α7 相互作用,阻止血管损伤后新内膜的形成。  |  Yu, Y., et al. 2022. J Biol Chem. 298: 101759. PMID: 35202649
  10. 整合素α7对子宫内膜癌细胞增殖, 侵袭, 凋亡和PI3K/AKT通路的影响及其与临床病理特征的关系。  |  Liang, M., et al. 2023. Oncol Lett. 25: 26. PMID: 36478908

订购信息

产品名称产品编号规格价格数量收藏夹

Integrin α7/ITGA7 抗体 (E-2)

sc-515716
200 µg/ml
RMB2377.00

Integrin α7/ITGA7 (E-2): m-IgG Fc BP-HRP 套装

sc-531479
200 µg Ab; 10 µg BP
RMB2662.00

Integrin α7/ITGA7 (E-2): m-IgGκ BP-HRP 套装

sc-525176
200 µg Ab, 40 µg BP
RMB2662.00

Integrin α7/ITGA7 (E-2): m-IgG1 BP-HRP 套装

sc-544580
200 µg Ab; 20 µg BP
RMB2662.00

Integrin α7/ITGA7 抗体 (E-2) AC

sc-515716 AC
500 µg/ml, 25% agarose
RMB3129.00

Integrin α7/ITGA7 抗体 (E-2) HRP

sc-515716 HRP
200 µg/ml
RMB2377.00

Integrin α7/ITGA7 抗体 (E-2) FITC

sc-515716 FITC
200 µg/ml
RMB2482.00

Integrin α7/ITGA7 抗体 (E-2) PE

sc-515716 PE
200 µg/ml
RMB2580.00

Integrin α7/ITGA7 抗体 (E-2) Alexa Fluor® 488

sc-515716 AF488
200 µg/ml
RMB2685.00

Integrin α7/ITGA7 抗体 (E-2) Alexa Fluor® 546

sc-515716 AF546
200 µg/ml
RMB2685.00

Integrin α7/ITGA7 抗体 (E-2) Alexa Fluor® 594

sc-515716 AF594
200 µg/ml
RMB2685.00

Integrin α7/ITGA7 抗体 (E-2) Alexa Fluor® 647

sc-515716 AF647
200 µg/ml
RMB2685.00

Integrin α7/ITGA7 抗体 (E-2) Alexa Fluor® 680

sc-515716 AF680
200 µg/ml
RMB2685.00

Integrin α7/ITGA7 抗体 (E-2) Alexa Fluor® 790

sc-515716 AF790
200 µg/ml
RMB2685.00

Integrin α7/ITGA7 抗体 (E-2) B

sc-515716 B
200 µg/ml
RMB2407.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with Integrin α7 (E-2): sc-515716 monoclonal antibody?

Asked by: AbPolly
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from good featurewe used this antibody to detect the expression of integrin in glioma cell lysate by western blot
Date published: 2017-09-25
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Integrin α7/ITGA7 抗体 (E-2) is rated 5.0 out of 5 by 1.
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