Date published: 2025-9-8

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IDO 抗体 (E-11): sc-365517

5.0(2)
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说明书
  • IDO抗体(E-11)是小鼠单克隆IgM (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于mouse物种的IDO的N-terminus附近的氨基酸11-35之间
  • 推荐用于 mouse, rat 和 human 来源的IDO WB, IP, IF 和 ELISA检测
  • 看 IDO (mIDO-48): sc-53978,可查看有标记的 IDO 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成IDO 抗体 (E-11)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    色氨酸2,3-双加氧酶(IDO)是一种IFN-γ可诱导的酶,催化必需氨基酸L-色氨酸降解为N-甲酰犬尿氨酸。编码人IDO的基因定位于8p12-p11染色体。IDO也称为INDO,是免疫学应答的重要调节剂,可保护同种异体概念免受同种异体反应性母体淋巴细胞的影响。IDO介导了与人PBLs共培养的HeLa细胞的有趣抑制作用。在HeLa细胞存在下,ILN-2诱导的PBL增殖应答减弱,而IDO抑制剂则消除了这种作用。流式细胞仪分析表明,成熟和未成熟的CD123阳性树突状细胞均使用IDO抑制T细胞活性。与T细胞共培养的IDO转染细胞可减少T细胞增殖。另外,供体T细胞的过继转移减少了IDO转基因小鼠中供体T细胞的数量。对IDO进行药理学或遗传学操作可能对于抑制不期望的T细胞应答是有用的。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    IDO 抗体 (E-11)

    sc-365517
    200 µg/ml
    $316.00

    IDO (E-11) 中和勝肽

    sc-365517 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-365517 P appropriate for?

    Asked by: Randy McDonald
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-24
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    Rated 5 out of 5 by from Great immunofluorescence cytoskeletal stainingGreat immunofluorescence cytoskeletal staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-02-11
    Rated 5 out of 5 by from Good Western Blot data of IDO expression in nonGood Western Blot data of IDO expression in non-transfected and mouse IDO transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-05-02
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    IDO 抗体 (E-11) is rated 5.0 out of 5 by 2.
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