Date published: 2025-9-7

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EDIL3 抗体 (4C9): sc-293337

4.5(2)
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说明书
  • EDIL3 抗体 4C9 是小鼠单克隆 IgG2a κ,EDIL3抗体, 在1篇文献中引用,规格为100 µg/ml
  • 免疫human物种的EDIL3的氨基酸101-199
  • 推荐用于 mouse, rat 和 human 来源的EDIL3 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取EDIL3 (4C9): sc-293337免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成EDIL3 抗体 (4C9)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

EDIL3抗体(4C9)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的EDIL3蛋白。抗EDIL3抗体(4C9)以非结合形式提供。EDIL3,也称为发育调节内皮细胞基因座1蛋白或整合素结合蛋白DEL1,是一种480个氨基酸的分泌型糖蛋白,在血管生成中起着至关重要的作用,尤其是在实体瘤形成过程中。EDIL3在胚胎内皮细胞中表达,并作为整合素αV/β3的配体,通过内源性血管生成信号通路促进内皮细胞粘附。这种相互作用对于胚胎发育过程中的血管形态发生至关重要,对于血管壁重塑也必不可少。EDIL3包含三个EGF样结构域和两个F5/8 C型结构域,由位于人类5q14.3号染色体上的基因编码,以两种可变剪接的同工型存在。EDIL3促进内皮细胞相互作用并参与血管生成,这凸显了它在发育生物学和癌症研究中的重要性,使得抗EDIL3抗体(4C9)成为研究这些过程的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

EDIL3 抗体 (4C9) 参考文献:

  1. Del1 通过连接 alphaVbeta3 诱导整合素信号和血管生成。  |  Penta, K., et al. 1999. J Biol Chem. 274: 11101-9. PMID: 10196194
  2. Del1:关节软骨表层的一种新蛋白质。  |  Pfister, BE., et al. 2001. Biochem Biophys Res Commun. 286: 268-73. PMID: 11500032
  3. Del1 通过与整合素 alpha(v)beta(3) 相互作用,介导血管内皮细胞的黏合剂, 迁移和增殖。  |  Rezaee, M., et al. 2002. Am J Physiol Heart Circ Physiol. 282: H1924-32. PMID: 11959660
  4. 胚胎血管生成因子 Del1 可通过促进血管形成来加速肿瘤生长。  |  Aoka, Y., et al. 2002. Microvasc Res. 64: 148-61. PMID: 12074641
  5. 通过基因传递细胞外基质蛋白 Del-1 使缺血组织血管新生。  |  Zhong, J., et al. 2003. J Clin Invest. 112: 30-41. PMID: 12840057
  6. Del-1 是一种内源性白细胞-内皮粘附抑制剂,可限制炎症细胞的招募。  |  Choi, EY., et al. 2008. Science. 322: 1101-4. PMID: 19008446
  7. 发育内皮基因座-1 的克隆和特征描述:一种能与 alphaavbeta3 整合素受体结合的胚胎内皮细胞蛋白。  |  Hidai, C., et al. 1998. Genes Dev. 12: 21-33. PMID: 9420328

订购信息

产品名称产品编号规格价格数量收藏夹

EDIL3 抗体 (4C9)

sc-293337
100 µg/ml
RMB2377.00

Can the sc-293337 EDIL-3 antibody be used for immunoprecipitation, western blotting and ELISA experiments?

Asked by: Vijaya
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-02-17

what is the molecular weight of the gelatin used in this antibody? Is it less than 50 KDa? Is it possible to order the antibody without the presence of gelatin? 

Asked by: Wagma
Thank you for your question. The molecular weight of the gelatin is 150-160 kDa. For customized antibody forms, please contact our Special orders department by emailing [email protected] .If you have additional questions, please contact Technical Support at 1800-457-3801 option 2, by emailing [email protected] or by live chat on our website at www.scbt.com so we may further assist you.
Answered by: Blake J
Date published: 2021-07-19

Can sc-293337: EDIL3 (4C9) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: DefinitelyNotMatt
Thank you for your question. Yes, sc-293337: EDIL3 (4C9) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Good for Western BlotAntibody detects EDIL3 in human pancreas extract by Western blot. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from EDIL3The edil3 antibody gave specific, strong detection in ES mouse cells.
Date published: 2017-10-03
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EDIL3抗体 (4C9) is rated 4.5 out of 5 by 2.
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