Date published: 2025-9-8
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DOT1L1 Antibody (E-2) - Western Blotting - Image 151747
DOT1L1 抗体 (E-2): sc-376036. 非转染: sc-117752 (A) 和小鼠 DOT1L1 转染: sc-178530 (B) 293T 全细胞裂解液中 DOT1L1 表达的 Western 印迹分析.
DOT1L1 Antibody (E-2) - Western Blotting - Image 151747
DOT1L1 抗体 (E-2): sc-376036. 非转染: sc-117752 (A) 和小鼠 DOT1L1 转染: sc-178530 (B) 293T 全细胞裂解液中 DOT1L1 表达的 Western 印迹分析.
DOT1L1 Antibody (E-2) - Western Blotting - Image 385151
DOT1L1 抗体 (E-2): sc-376036. Western 印迹分析 AMJ2-C8 全细胞裂解液中 DOT1L1 的表达.
DOT1L1 抗体 (E-2): sc-376036. 非转染: sc-117752 (A) 和小鼠 DOT1L1 转染: sc-178530 (B) 293T 全细胞裂解液中 DOT1L1 表达的 Western 印迹分析.

DOT1L1 抗体 (E-2): sc-376036

4.0(4)
寫評論提問

说明书
  • DOT1L1抗体(E-2)是小鼠单克隆IgG2b κ, 在1篇文献中引用，规格为200 µg/ml
  • 免疫原氨基酸序列1-300位于human物种的DOT1L1的N-terminal
  • 推荐用于 mouse, rat 和 human 来源的DOT1L1 WB, IP, IF 和 ELISA检测
  • 可用于ChIP的TransCruz试剂(sc-376036 X, 200 µg/0.1 ml)
  • 2b BP-HRP">m-IgG2b BP-HRP是DOT1L1 Antibody (E-2) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与DOT1L1 Antibody (E-2) 打包提供（请参阅下面的订购信息）。

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描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

DOT1L1，又称 DOT1L（DOT1样组蛋白H3甲基转移酶），DOT1或KMT4，它由1739个氨基酸组成，是酵母DOT1（端粒沉默干扰体-1）蛋白的同系物。DOT1L1定位在细胞核，在睾丸、肺和肾脏中高度表达，是一种组蛋白甲基转移酶，它可将甲基从S-腺苷-L-甲硫氨酸转移到各种底物（如核小体或组蛋白）的赖氨酸残基上。虽然大多数组蛋白甲基转移酶含有SET结构域，该结构域赋予其酶活性，但DOT1L1并没有该结构域，因此认为它的作用机制截然不同。DOT1L1可与急性白血病中发现的MLL融合伴侣蛋白结合，由此促进肿瘤形成。选择性剪接使DOT1L1存在两种亚型。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

DOT1L1 抗体 (E-2)

sc-376036
200 µg/ml
RMB2377.00

DOT1L1 (E-2): m-IgG2b BP-HRP 套装

sc-548584
200 µg Ab; 10 µg BP
RMB2662.00

DOT1L1 抗体 (E-2) X

sc-376036 X
200 µg/0.1 ml
RMB2377.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-376036: DOT1L1 (E-2) mouse monoclonal antibody will work?

Asked by: Randy McDonald
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 1 out of 5 by from Not good for IPIt can not pull down itself in co-IP experiment using human cell nuclear extract.
Date published: 2017-06-24
Rated 5 out of 5 by from weston blotWe tested it by weston blot 3 month ago. Its band is clear for WB detection by dilution 1:800.
Date published: 2017-05-28
Rated 5 out of 5 by from Bands were clear.It was used to detect DOT1L1 in mouse liver tissue. Bands were clear.
Date published: 2017-02-26
Rated 5 out of 5 by from Great Western blot data of DOT1L1 expressionGreat Western blot data of DOT1L1 expression in non-transfected and mouse DOT1L1 transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-10-11
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DOT1L1 抗体 (E-2) is rated 4.0 out of 5 by 4.
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