Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

DOT1L1 抗体 (C-3): sc-390879

5.0(2)
寫評論提問

说明书
  • DOT1L1抗体(C-3)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的DOT1L1的内部区域内的氨基酸1515-1528之间
  • 推荐用于 mouse, rat 和 human 来源的DOT1L1 WB, IP, IF 和 ELISA检测
  • 目前,我们还没有完成DOT1L1 抗体 (C-3)的首选二抗检测试剂的鉴定。这项工作正在进行中。

快捷链接

関連項目

DOT1L1,又称 DOT1L(DOT1样组蛋白H3甲基转移酶),DOT1或KMT4,它由1739个氨基酸组成,是酵母DOT1(端粒沉默干扰体-1)蛋白的同系物。DOT1L1定位在细胞核,在睾丸、肺和肾脏中高度表达,是一种组蛋白甲基转移酶,它可将甲基从S-腺苷-L-甲硫氨酸转移到各种底物(如核小体或组蛋白)的赖氨酸残基上。虽然大多数组蛋白甲基转移酶含有SET结构域,该结构域赋予其酶活性,但DOT1L1并没有该结构域,因此认为它的作用机制截然不同。DOT1L1可与急性白血病中发现的MLL融合伴侣蛋白结合,由此促进肿瘤形成。选择性剪接使DOT1L1存在两种亚型。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

DOT1L1 抗体 (C-3)

sc-390879
200 µg/ml
RMB2377.00

DOT1L1 (C-3) 中和勝肽

sc-390879 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-390879 P appropriate for?

Asked by: jerojero
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_390879, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 103ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Great monoclonal antibodyStrong signal by Western blot with transfected lysate
Date published: 2017-02-06
Rated 5 out of 5 by from Good Western Blot data of DOT1L1 expression in nonGood Western Blot data of DOT1L1 expression in non-transfected and mouse DOT1L1 transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-12-16
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_390879, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 17ms
  • REVIEWS, PRODUCT
DOT1L1 抗体 (C-3) is rated 5.0 out of 5 by 2.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_390879, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 103ms
  • REVIEWS, PRODUCT