Date published: 2025-9-7

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Clusterin-α 抗体 (A-11): sc-166831

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说明书
  • Clusterin-α抗体(A-11)是小鼠单克隆IgG2a κ, 在5篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Clusterin-α的C-terminus的氨基酸432-449之间
  • 抗-Clusterin-alpha 抗体 (A-11) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 Clusterin-α
  • 抗Clusterin-alpha抗体(A-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Clusterin-α (A-11): sc-166831免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Clusterin-α Antibody (A-11) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与Clusterin-α Antibody (A-11) 打包提供(请参阅下面的订购信息)。

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関連項目

Clusterin-α抗体(A-11)是一种IgG2a κ小鼠单克隆Clusterin-α抗体,能够通过WB、IP、IF、IHC(P)和ELISA等方法检测小鼠、大鼠和人类来源的Clusterin-α。该抗体以非偶联的抗Clusterin-α抗体形式提供,同时也提供多种偶联形式的抗Clusterin-α抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Clusterin,也被称为补体溶解抑制剂(CLI)、载脂蛋白J(ApoJ)、硫酸化糖蛋白2(SGP2)、SP-40和睾酮抑制的前列腺信息素2(TRPM2),是一种分泌型、异二聚体糖蛋白,具有调节免疫、细胞粘附、转化、脂质运输、组织重塑、膜再循环和细胞间相互作用的功能。Clusterin由449个氨基酸组成的多肽合成,翻译后会在Arg 227和Ser 228之间的内部键处被切割。其两个亚基α和β通过二硫键连接,其中β亚基(也称为ApoJα)对应于残基23-227,而α亚基(也称为ApoJβ)对应于残基228-449。在乳腺肿瘤进展的晚期,Clusterin的过度表达更为常见。此外,Clusterin在体内显著影响β-淀粉样蛋白结构和神经毒性,并可能影响阿尔茨海默病的发病机理。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

Clusterin-α 抗体 (A-11)

sc-166831
200 µg/ml
RMB2377.00

Clusterin-α (A-11): m-IgG Fc BP-HRP 套装

sc-529063
200 µg Ab; 10 µg BP
RMB2662.00

Clusterin-α (A-11): m-IgGκ BP-HRP 套装

sc-521762
200 µg Ab, 40 µg BP
RMB2662.00

Clusterin-α (A-11): m-IgG2a BP-HRP 套装

sc-547253
200 µg Ab; 10 µg BP
RMB2662.00

Clusterin-α 抗体 (A-11) AC

sc-166831 AC
500 µg/ml, 25% agarose
RMB3129.00

Clusterin-α 抗体 (A-11) HRP

sc-166831 HRP
200 µg/ml
RMB2377.00

Clusterin-α 抗体 (A-11) FITC

sc-166831 FITC
200 µg/ml
RMB2482.00

Clusterin-α 抗体 (A-11) PE

sc-166831 PE
200 µg/ml
RMB2580.00

Clusterin-α 抗体 (A-11) Alexa Fluor® 488

sc-166831 AF488
200 µg/ml
RMB2685.00

Clusterin-α 抗体 (A-11) Alexa Fluor® 546

sc-166831 AF546
200 µg/ml
RMB2685.00

Clusterin-α 抗体 (A-11) Alexa Fluor® 594

sc-166831 AF594
200 µg/ml
RMB2685.00

Clusterin-α 抗体 (A-11) Alexa Fluor® 647

sc-166831 AF647
200 µg/ml
RMB2685.00

Clusterin-α 抗体 (A-11) Alexa Fluor® 680

sc-166831 AF680
200 µg/ml
RMB2685.00

Clusterin-α 抗体 (A-11) Alexa Fluor® 790

sc-166831 AF790
200 µg/ml
RMB2685.00

Clusterin-α (A-11) 中和勝肽

sc-166831 P
100 µg/0.5 ml
RMB511.00

Hi, since alpha chain of clusterin=ApoJ-beta, and beta chain=APoJ-alpha, then which end of the protein does the A-11 antibody called clusterin-alpha detects? Does it react with N or C -terminal fragment of the protein?

Asked by: jackie27111
Thank you for your question. This antibody is specific for an epitope mapping between amino acids 420-449 at the C-terminus of Clusterin-α of human origin (accession#P10909).
Answered by: Tech Service
Date published: 2019-12-06

We need to test expression of equine clusterin. We will much appreciate if you send us a sample of this and other anticlusterin Ab to test. Once we confirm the cross reactivity (WIB, IHQ) we can give you validation and purchase the one of best results.

Asked by: MonicaVL
Thank you for your question. Please contact your local distributor or information on how to obtain a sample.
Answered by: Technical Support
Date published: 2018-12-14

What application is the blocking peptide sc-166831 P appropriate for?

Asked by: cjMara
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Excellent!This antibody is great in western blot analysis of Clusterin-α expression in A549, SK-BR-3 and PANC-1 whole cell lysates.
Date published: 2017-02-08
Rated 5 out of 5 by from Produced exceptional immunoperoxidase cytoplasmicProduced exceptional immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human pancreas tissue. -SCBT QC
Date published: 2015-02-16
Rated 5 out of 5 by from Nice Western Blot data of Clusterin expressionNice Western Blot data of Clusterin expression in non-transfected and human Clusterin transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-11-17
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Clusterin-α 抗体 (A-11) is rated 5.0 out of 5 by 3.
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