Date published: 2025-9-7
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beta-catenin Antibody (10H8) - Western Blotting - Image 34790
β-catenin (10H8): sc-65480. 非转染: sc-117752 (A) 和人 β-catenin 转染: sc-116622 (B) 293T 全细胞裂解液中 β-catenin 表达的 Western 印迹分析.
beta-catenin Antibody (10H8) - Western Blotting - Image 34790
β-catenin (10H8): sc-65480. 非转染: sc-117752 (A) 和人 β-catenin 转染: sc-116622 (B) 293T 全细胞裂解液中 β-catenin 表达的 Western 印迹分析.
beta-catenin Antibody (10H8) - Western Blotting - Image 34754
β-catenin (10H8): sc-65480. 对 MCF7 全细胞裂解液中 β-catenin 的表达进行 Western 印迹分析.
β-catenin (10H8): sc-65480. 非转染: sc-117752 (A) 和人 β-catenin 转染: sc-116622 (B) 293T 全细胞裂解液中 β-catenin 表达的 Western 印迹分析.

beta-catenin 抗体 (10H8): sc-65480

4.1(7)
寫評論提問

说明书
  • beta-catenin 抗体 10H8 是小鼠单克隆 IgG2a, 在27篇文献中引用，提供 50 µg/0.5 ml
  • 免疫human物种的β-catenin的氨基酸769-781
  • 推荐用于 mouse, rat 和 human 来源的the C terminus of β-catenin WB, IP 和 IF检测
  • 看 beta-catenin (E-5): sc-7963，可查看有标记的 beta-catenin 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前，我们还没有完成beta-catenin 抗体 (10H8)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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描述
基因信息
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研究信息

関連項目

此外 Catenin 抗体包括 α E-catenin, α T-catenin, β-catenin, δ-catenin 和 γ-catenin

β-catenin抗体（10H8）是一种小鼠单克隆IgG2a抗体，靶向人β-catenin的769-781个氨基酸。β-catenin具有独特的结构，包括一个由12个犰狳重复序列组成的超螺旋结构中心区域，因此是细胞-细胞粘附和Wnt信号通路不可或缺的部分。这种结构特征使β-catenin能够与不同的伙伴相互作用，包括粘连连接处的E-cadherin，β-catenin在粘连连接处将E-cadherin的胞浆尾部与肌动蛋白细胞骨架连接起来，确保组织的内聚力和信号转导。在 Wnt 信号转导过程中，β-catenin 稳定在细胞质中，并转运到细胞核，调节对细胞生长和分化至关重要的基因。β-catenin的失调与异常细胞过程有关，突出了β-catenin在维持细胞稳态方面的重要性。抗β-catenin抗体（10H8）可用于免疫印迹（WB）、免疫沉淀（IP）和免疫荧光（IF）等应用，并能与来自人、小鼠和大鼠的β-catenin发生反应。通过特异性靶向 β-catenin 的 C 端，β-catenin 单克隆抗体 (10H8) 可为粘附机制和信号通路研究提供可靠的检测。抗β-catenin抗体（10H8）是研究这种多功能蛋白的结构和功能动态的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

beta-catenin 抗体 (10H8)

sc-65480
50 µg/0.5 ml
RMB2377.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with β-catenin (10H8): sc-65480 antibody?

Asked by: cjMara
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 3 out of 5 by from blotting works well and specificsingle band by blot. used at 1:250 dilution, works well for multiple species.
Date published: 2018-03-12
Rated 5 out of 5 by from GreatVery happy. Ab worked very good for mouse spleen WB.
Date published: 2017-03-20
Rated 5 out of 5 by from works perfectly for the WB applicationExcellent antibody. It works perfectly for the WB application. I tested the following dilutions 1:2000, 1:5000, 1:8000
Date published: 2017-01-19
Rated 5 out of 5 by from positiive staining of mouse tissuewe use this antibody for years.It is very nice. We use the dilution 1:200,this dilution is enough to get the target band.
Date published: 2016-12-14
Rated 4 out of 5 by from Good for Western blot as well as immunostainingGood for Western blot as well as immunostaining.
Date published: 2016-08-05
Rated 3 out of 5 by from Worked with transfected lysate by WB withWorked with transfected lysate by WB with some background -SCBT QC
Date published: 2015-05-07
Rated 4 out of 5 by from Performs well in WesternPerforms well in Western, good signal strength in MCF7. -SCBT QC
Date published: 2013-07-25
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beta-catenin 抗体 (10H8) is rated 4.1 out of 5 by 7.
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