Date published: 2025-9-7
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BAF60a Antibody (23) - Western Blotting - Image 386081
BAF60a 抗体 (23): sc-135843. Jurkat (A) 和 Neuro-2A (B) 全细胞裂解液以及 A549 (C), SK-N-MC (D), NIH/3T3 (E) 和 HeLa (F) 核提取物中 BAF60a 表达的 Western 印迹分析.
BAF60a 抗体 (23): sc-135843. Jurkat (A) 和 Neuro-2A (B) 全细胞裂解液以及 A549 (C), SK-N-MC (D), NIH/3T3 (E) 和 HeLa (F) 核提取物中 BAF60a 表达的 Western 印迹分析.

BAF60a 抗体 (23): sc-135843

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说明书
  • BAF60a 抗体 23 是小鼠单克隆 IgG2a, 在30篇文献中引用，提供 200 µg/ml
  • 免疫mouse物种的BAF60a的氨基酸1-91
  • 推荐用于 mouse, rat, human 和 canine 来源的BAF60a WB, IP 和 IF检测
  • 关于如何获取BAF60a (23): sc-135843的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP和 2a BP-HRP">m-IgG2a BP-HRP是BAF60a Antibody (23) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与BAF60a Antibody (23) 打包提供（请参阅下面的订购信息）。

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関連項目

额外BAF抗体，包括BAF155, BAF170, BAF53, BAF57和BAF60a

BAF60a抗体（23）是一种IgG2a小鼠单克隆BAF60a抗体，可通过WB、IP和IF检测小鼠、大鼠和人类来源的BAF60a。BAF60a抗体（23）可作为非偶联抗BAF60a抗体形式提供。BAF60a（BRG1相关因子60A），也称为SMARCD1（SWI/SNF相关，基质相关，肌动蛋白依赖性染色质调节因子，亚家族d，成员1）、Rsc6p或CRACD1，是一种476个氨基酸的蛋白质，定位于细胞核，并含有一个SWIB结构域。BAF60a在肝脏、大脑、肌肉、肺、肾脏、胰腺和胎盘中显著表达，作为BAF复合物的组成部分，与多种其他蛋白质结合，在染色质重塑中发挥着重要作用。此外，BAF60a影响维生素D介导的转录活性，并被认为在维生素D受体（VDR）和SWI/SNF染色质重塑复合物之间提供了联系。由于选择性剪接事件的存在，BAF60a存在多种异构体。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

BAF60a 抗体 (23) 参考文献:

  1. 由 SWI/SNF 亚基重构核心染色质重塑复合物。  |  Phelan, ML., et al. 1999. Mol Cell. 3: 247-53. PMID: 10078207
  2. 鉴定SWI.SNF复合体亚基BAF60a是Fos/Jun二聚体转录激活潜力的决定因素  |  Ito, T., et al. 2001. J Biol Chem. 276: 2852-7. PMID: 11053448
  3. 人类 SWI/SNF-B 染色质重塑复合物与酵母 rsc 有关，定域于有丝分裂染色体的着丝点。  |  Xue, Y., et al. 2000. Proc Natl Acad Sci U S A. 97: 13015-20. PMID: 11078522
  4. 新型 SWI/SNF 染色质重塑复合物含有一种混合系白血病染色体易位伙伴。  |  Nie, Z., et al. 2003. Mol Cell Biol. 23: 2942-52. PMID: 12665591
  5. 染色质重塑复合物 WINAC 将核受体靶向启动子，并在威廉姆斯综合征中受损。  |  Kitagawa, H., et al. 2003. Cell. 113: 905-17. PMID: 12837248
  6. BAF60a 介导核受体与 BRG1 染色质重塑复合物之间的重要相互作用，以实现转录激活。  |  Hsiao, PW., et al. 2003. Mol Cell Biol. 23: 6210-20. PMID: 12917342
  7. BAF60a/BAF60c 在染色质重塑和肝脏脂质代谢中的作用  |  Zhang, P., et al. 2016. Nutr Metab (Lond). 13: 30. PMID: 27127533
  8. 核磁共振光谱发现了 BAF60A 与 p53 之间的直接相互作用。  |  Han, J., et al. 2021. Biochem Biophys Res Commun. 534: 815-821. PMID: 33168186
  9. 巨噬细胞中 BAF60a 的缺乏会促进饮食诱发的肥胖和代谢性炎症。  |  Kong, Q., et al. 2022. Diabetes. 71: 2136-2152. PMID: 35822944
  10. 髓细胞 BAF60a 缺乏会改变代谢平衡并加剧动脉粥样硬化。  |  Zhao, Y., et al. 2023. Cell Rep. 42: 113171. PMID: 37768825
  11. 哺乳动物 SWI/SNF 复合物的多样性和特化。  |  Wang, W., et al. 1996. Genes Dev. 10: 2117-30. PMID: 8804307
  12. 人类基因组中分布着五个与 SWI/SNF 相关, 与基质缔合作用相关, 依赖肌动蛋白的染色质调控因子（SMARC）基因。  |  Ring, HZ., et al. 1998. Genomics. 51: 140-3. PMID: 9693044

订购信息

产品名称产品编号规格价格数量收藏夹

BAF60a 抗体 (23)

sc-135843
200 µg/ml
RMB2377.00

BAF60a (23): m-IgG Fc BP-HRP 套装

sc-525750
200 µg Ab; 10 µg BP
RMB2662.00

BAF60a (23): m-IgG2a BP-HRP 套装

sc-546396
200 µg Ab; 10 µg BP
RMB2662.00

I have some feline samples that I am testing. Will this antibody cross-react?

Asked by: Cweed
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 13
Date published: 2017-01-20
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Rated 5 out of 5 by from Baf60a (23) used for western blot applicationGreat clean bands at expected molecular size. 2.4ug of antibody per blot was diluted in 3%BSA PBS1x-tween0.05%, 7ul/14ml per blot.
Date published: 2018-03-07
Rated 5 out of 5 by from GreatThis antibody can detect endogenous BAF60a in Jurkat cells, worked perfectly
Date published: 2017-05-20
Rated 5 out of 5 by from Great productStrong western blot data with low background; superb IF staining
Date published: 2017-02-03
Rated 5 out of 5 by from Great choice!This is a great antibody for detecting BAF60a. It gives strong staining in IF and nice single bands in WB.
Date published: 2016-12-16
Rated 4 out of 5 by from Decent WB band obtained using the antibodyDecent WB band obtained using the antibody against Jurkat whole cell lysate. -SCBT QC
Date published: 2015-06-14
Rated 4 out of 5 by from WB publishable data with nuclear proteinWB publishable data with nuclear protein extracts from mouse embryonic (mESC) and epiblast (mEpiSC) stem cells - SCBT Publication Review
Date published: 2015-05-09
Rated 5 out of 5 by from Good WB publishable data gathered with mouseGood WB publishable data gathered with mouse nuclear protein extracts from mouse embryonic (mESC) and epiblast (mEpiSC) stem cells -SCBT Publication Review
Date published: 2015-03-10
Rated 4 out of 5 by from Great immunofluorescence nuclear stainingGreat immunofluorescence nuclear staining in human endothelial cells. -SCBT QC
Date published: 2014-12-15
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BAF60a 抗体 (23) is rated 4.6 out of 5 by 8.
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