Anticorps L3MBTL (D-10): sc-398603
- L'Anticorps L3MBTL (D-10) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 581-665 situés près de la région C-terminus de L3MBTL d'origine human
- recommandé pour la détection de L3MBTL d'origine human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps L3MBTL (D-10) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps L3MBTL (D-10)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
L3MBTL is member of the Polycomb group of proteins that function as transcriptional repressors in large protein complexes. L3MBTL contains three repeats of 100 residues called MBT repeats, and a C-terminal alpha-helical structure within a cavity lined by aromatic amino acids. The protein undergoes monoallelic methylation in hematopoietic tissues and is expressed in most human adult normal tissues. During interphase, L3MBTL localizes to the nucleus and completely associates with condensed chromosomes in mitotic cells. Together with Trithorax group proteins, L3MBTL is responsible for the coordinated regulation of patterns of gene activity. The human L3MBTL gene lies in a region of chromosome 20 that is frequently deleted in patients with myeloid malignancies and has been proposed as a candidate 20q tumor suppressor gene, implicating L3MBTL expression in some cases of myeloid leukemia.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps L3MBTL (D-10) | sc-398603 | 200 µg/ml | RMB2377.00 | |||
L3MBTL (D-10): m-IgG Fc BP-HRP Kit | sc-538478 | 200 µg Ab; 10 µg BP | RMB2662.00 | |||
L3MBTL (D-10): m-IgGκ BP-HRP Kit | sc-536100 | 200 µg Ab; 40 µg BP | RMB2662.00 | |||
L3MBTL (D-10): m-IgG1 BP-HRP Kit | sc-545722 | 200 µg Ab; 20 µg BP | RMB2662.00 |