Date published: 2025-9-8

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Zyxin激活剂

MYH11 activators belong to a distinct chemical class known for their ability to modulate the activity of the MYH11 gene. MYH11, short for "myosin heavy chain 11," is a crucial protein involved in the contraction of smooth muscle cells. Smooth muscles are found in various organs and tissues throughout the body, including the blood vessels, airways, and gastrointestinal tract. The MYH11 gene encodes a myosin protein specifically expressed in smooth muscle cells, and its activation plays a fundamental role in regulating smooth muscle contraction. MYH11 activators, therefore, are compounds or molecules that exert an influence on MYH11 expression or function, ultimately impacting the contractility of smooth muscles.

The exact mechanisms through which MYH11 activators operate can vary, but they typically act at the molecular level. Some MYH11 activators may enhance the transcription or expression of the MYH11 gene, leading to increased production of the MYH11 protein. Others may directly interact with the MYH11 protein, altering its conformation or function to promote smooth muscle contraction. These activators can be of significant interest in scientific research and may have potential applications in understanding various physiological processes, such as vascular tone regulation, airway constriction, and gastrointestinal motility. Additionally, studying MYH11 activators can help elucidate the intricate signaling pathways and molecular events involved in smooth muscle function, contributing to a broader understanding of cellular biology and potentially paving the way for future developments in related fields.

関連項目

产品名称CAS #产品编号数量价格应用排名

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
¥451.00
¥1455.00
¥2369.00
¥5528.00
¥10481.00
119
(6)

PMA 是蛋白激酶 C (PKC) 的强效激活剂,可激活各种信号通路。PKC 激活可影响细胞过程,从而可能影响 Zyxin 在细胞骨架组织和细胞粘附中的作用。

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
¥2053.00
¥7818.00
88
(1)

Y-27632 是一种 Rho 激酶(ROCK)抑制剂。通过抑制 ROCK,它可以调节参与细胞骨架动力学和细胞粘附的 RhoA-ROCK 通路,从而间接影响 Zyxin。

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
¥925.00
¥1692.00
¥4377.00
113
(4)

Staurosporine 是一种广谱蛋白激酶抑制剂。它可以调节各种信号通路,通过影响下游信号级联间接影响 Zyxin 的活性。

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
¥1681.00
¥5303.00
¥6995.00
¥13527.00
¥23579.00
33
(3)

Trichostatin A 是一种组蛋白去乙酰化酶(HDAC)抑制剂。它可以影响基因表达,并可能通过调节相关基因的转录物间接影响 Zyxin。

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
¥451.00
¥824.00
¥2448.00
¥2730.00
¥8168.00
¥13493.00
39
(2)

紫杉醇是一种微管稳定剂。通过稳定微管,它可以间接影响与细胞骨架动力学和细胞形态有关的 Zyxin 相关过程。

Calpeptin

117591-20-5sc-202516
sc-202516A
10 mg
50 mg
¥1343.00
¥5043.00
28
(1)

Calpeptin 是一种钙蛋白酶抑制剂。钙蛋白酶是一种钙依赖蛋白酶,可以裂解 Zyxin。抑制钙蛋白酶的活性可间接维持 Zyxin 的水平。

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
¥1365.00
¥4423.00
148
(1)

LY294002 是一种 PI3K(磷酸肌醇 3-激酶)抑制剂。通过抑制 PI3K,它可以调节下游信号通路,从而对 Zyxin 相关的细胞功能产生潜在影响。

EHT 1864

754240-09-0sc-361175
sc-361175A
10 mg
50 mg
¥2358.00
¥9838.00
12
(2)

EHT 1864 是一种 Rac1 抑制剂。通过抑制 Rac1,它可以影响肌动蛋白动力学和细胞运动,间接影响 Zyxin 的活性。