Date published: 2025-9-8

021-6093-6350

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Peg10 抑制因子

Peg10 Inhibitors refer to a diverse class of chemical compounds designed to target and modulate the activity of the PEG10 gene, primarily by interfering with its expression or function. PEG10, which stands for Paternally Expressed Gene 10, is a unique imprinted gene in mammals, implicated in various cellular processes, including cell proliferation, apoptosis, and cancer development. Inhibitors within this class act as valuable tools for researchers and scientists to investigate the intricate mechanisms through which PEG10 influences these processes. These compounds exhibit diverse chemical structures and mechanisms of action, enabling a comprehensive exploration of PEG10's roles in cellular biology.

The mechanisms by which Peg10 Inhibitors function can vary widely. Some compounds focus on epigenetic regulation, impacting PEG10 gene expression by targeting DNA methylation or histone modifications within its regulatory regions. Others may affect post-transcriptional processing, mRNA stability, or translation of PEG10 transcripts. Additionally, Peg10 Inhibitors can potentially interfere with the interactions between PEG10 and its downstream targets, inhibiting specific cellular pathways or signaling cascades associated with PEG10 function. By providing a suite of chemical tools to manipulate PEG10, this class of inhibitors empowers researchers to unravel the complex web of molecular events associated with PEG10's role in normal cellular physiology and disease states. Understanding the mechanisms and consequences of PEG10 inhibition can pave the way for new insights into the fundamental biology of this gene and its potential implications in various biological contexts.

関連項目

产品名称CAS #产品编号数量价格应用排名

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
¥1422.00
¥3136.00
¥11101.00
3
(1)

Zebularine是一种DNA甲基转移酶抑制剂,可阻止PEG10启动子区域的甲基化,从而降低PEG10基因的表达。

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
¥2414.00
¥3565.00
¥4716.00
7
(1)

这种抑制剂也被称为地西他滨,其作用类似于齐伯拉林,抑制 DNA 甲基转移酶,使 PEG10 启动子去甲基化。

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
¥1444.00
¥5697.00
2
(1)

RG108 是一种 DNA 甲基转移酶小分子抑制剂,其中包括参与 PEG10 启动子甲基化的甲基转移酶。

Scriptaid

287383-59-9sc-202807
sc-202807A
1 mg
5 mg
¥711.00
¥2019.00
11
(2)

Scriptaid 是一种组蛋白去乙酰化酶(HDAC)抑制剂,可调节表观遗传调控,间接影响 PEG10 的表达。

5-Azacytidine

320-67-2sc-221003
500 mg
¥3159.00
4
(1)

这种胞苷类似物可结合到 DNA 中并抑制 DNA 甲基转移酶,从而影响 PEG10 启动子的甲基化。

Valproic Acid

99-66-1sc-213144
10 g
¥959.00
9
(1)

丙戊酸是一种 HDAC 抑制剂,可通过改变组蛋白乙酰化模式来影响 PEG10 的表达。

UNC0638

1255580-76-7sc-397012
10 mg
¥3554.00
(0)

UNC0638 是一种 G9a 组蛋白甲基转移酶抑制剂,通过组蛋白甲基化变化间接影响 PEG10 的表达。

EPZ6438

1403254-99-8sc-507456
1 mg
¥745.00
(0)

EPZ-6438 是一种 EZH2 组蛋白甲基转移酶抑制剂,可通过影响组蛋白甲基化模式来调节 PEG10 的表达。