Peg10 Inhibitors refer to a diverse class of chemical compounds designed to target and modulate the activity of the PEG10 gene, primarily by interfering with its expression or function. PEG10, which stands for Paternally Expressed Gene 10, is a unique imprinted gene in mammals, implicated in various cellular processes, including cell proliferation, apoptosis, and cancer development. Inhibitors within this class act as valuable tools for researchers and scientists to investigate the intricate mechanisms through which PEG10 influences these processes. These compounds exhibit diverse chemical structures and mechanisms of action, enabling a comprehensive exploration of PEG10's roles in cellular biology.
The mechanisms by which Peg10 Inhibitors function can vary widely. Some compounds focus on epigenetic regulation, impacting PEG10 gene expression by targeting DNA methylation or histone modifications within its regulatory regions. Others may affect post-transcriptional processing, mRNA stability, or translation of PEG10 transcripts. Additionally, Peg10 Inhibitors can potentially interfere with the interactions between PEG10 and its downstream targets, inhibiting specific cellular pathways or signaling cascades associated with PEG10 function. By providing a suite of chemical tools to manipulate PEG10, this class of inhibitors empowers researchers to unravel the complex web of molecular events associated with PEG10's role in normal cellular physiology and disease states. Understanding the mechanisms and consequences of PEG10 inhibition can pave the way for new insights into the fundamental biology of this gene and its potential implications in various biological contexts.
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
---|---|---|---|---|---|---|
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | ¥1422.00 ¥3136.00 ¥11101.00 | 3 | |
Zebularine是一种DNA甲基转移酶抑制剂,可阻止PEG10启动子区域的甲基化,从而降低PEG10基因的表达。 | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | ¥2414.00 ¥3565.00 ¥4716.00 | 7 | |
这种抑制剂也被称为地西他滨,其作用类似于齐伯拉林,抑制 DNA 甲基转移酶,使 PEG10 启动子去甲基化。 | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | ¥1444.00 ¥5697.00 | 2 | |
RG108 是一种 DNA 甲基转移酶小分子抑制剂,其中包括参与 PEG10 启动子甲基化的甲基转移酶。 | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | ¥711.00 ¥2019.00 | 11 | |
Scriptaid 是一种组蛋白去乙酰化酶(HDAC)抑制剂,可调节表观遗传调控,间接影响 PEG10 的表达。 | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | ¥3159.00 | 4 | |
这种胞苷类似物可结合到 DNA 中并抑制 DNA 甲基转移酶,从而影响 PEG10 启动子的甲基化。 | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | ¥959.00 | 9 | |
丙戊酸是一种 HDAC 抑制剂,可通过改变组蛋白乙酰化模式来影响 PEG10 的表达。 | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | ¥3554.00 | ||
UNC0638 是一种 G9a 组蛋白甲基转移酶抑制剂,通过组蛋白甲基化变化间接影响 PEG10 的表达。 | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | ¥745.00 | ||
EPZ-6438 是一种 EZH2 组蛋白甲基转移酶抑制剂,可通过影响组蛋白甲基化模式来调节 PEG10 的表达。 |