MDR 抗体和相关产品
圣克鲁斯生物技术公司（Santa Cruz Biotechnology）拥有多种针对多药耐药性蛋白的 MDR 抗体。MDR 抗体适用于 Western 印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组化 (IHCP)、流式细胞术 (FCM) 和酶联免疫吸附试验 (ELISA)。多药耐药性蛋白可促进药物和其他物质在细胞膜上的转运，极大地影响化疗和其他治疗干预措施的疗效。了解多药耐药蛋白的功能和调控对于制定克服癌症治疗中耐药性的策略至关重要。对多药耐药蛋白的研究将继续推动个性化医疗的发展，改善患者的治疗效果。多药耐药蛋白研究揭示了细胞防御机制和治疗耐药模式的重要见解。对 MDR 蛋白的持续研究有助于确定新的治疗靶点和潜在的耐药性标记物。利用圣克鲁斯生物技术公司单克隆抗体进行的研究有助于在全球范围内推进癌症治疗策略和改善治疗效果。
MDR 抗体
| Empty Table Header | 产品名称 | 目录 | 亚型 | 抗原决定簇 | 应用 | Species | 应用 | 排名 |
|---|---|---|---|---|---|---|---|---|
MDR1/ABCB1 抗体 (D-11) | sc-55510 | mouse IgG2b κ | 1040-1280 (h) | WB, IP, IF, IHC(P), ELISA | m, r, h | 187 | ||
MDR1/ABCB1 抗体 (G-1) | sc-13131 | mouse IgG2b κ | 1040-1280 (h) | WB, IP, IF, IHC(P), ELISA | h | 115 | ||
MDR1/ABCB1 抗体 (UIC2) | sc-73354 | mouse IgG2a κ | FL (h) | IP, IF, IHC(P), FCM | h | 31 | ||
MDR3/ABCB4 抗体 (P3-II-26) | sc-551480 | mouse IgG2b | 629-692 (h) | WB, IP, IF, FCM | h | new |
MDR CRISPR 敲除，HDR 和双切口酶质粒
| Empty Table Header | 产品名称 | 目录 | Species | 应用 | 标记物 | 应用 | 排名 |
|---|---|---|---|---|---|---|---|
MDR1/ABCB1 CRISPR/Cas9 KO质粒 (h) | sc-400178 | h | Gene Knockout | GFP | 0 | ||
MDR1/ABCB1 HDR 质粒 (h) | sc-400178-HDR | h | Homology Directed Repair | Puromycin | 0 | ||
MDR1/ABCB1双切口酶质粒(h) | sc-400178-NIC | h | Gene Knockout | Puromycin | 0 | ||
MDR1/ABCB1双切口酶质粒(h2) | sc-400178-NIC-2 | h | Gene Knockout | Puromycin | 0 | ||
MDR1/ABCB1 CRISPR/Cas9 KO质粒 (m) | sc-422215 | m | Gene Knockout | GFP | 0 | ||
MDR1/ABCB1 HDR 质粒 (m) | sc-422215-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
MDR1/ABCB1双切口酶质粒(m) | sc-422215-NIC | m | Gene Knockout | Puromycin | 0 | ||
MDR1/ABCB1双切口酶质粒(m2) | sc-422215-NIC-2 | m | Gene Knockout | Puromycin | 0 | ||
MDR2/ABCB4 CRISPR/Cas9 KO质粒 (m) | sc-422216 | m | Gene Knockout | GFP | 0 | ||
MDR2/ABCB4 HDR 质粒 (m) | sc-422216-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
MDR2/ABCB4双切口酶质粒(m) | sc-422216-NIC | m | Gene Knockout | Puromycin | 0 | ||
MDR2/ABCB4双切口酶质粒(m2) | sc-422216-NIC-2 | m | Gene Knockout | Puromycin | 0 | ||
MDR3/ABCB4 CRISPR/Cas9 KO质粒 (h) | sc-404167 | h | Gene Knockout | GFP | 0 | ||
MDR3/ABCB4 HDR 质粒 (h) | sc-404167-HDR | h | Homology Directed Repair | Puromycin | 0 | ||
MDR3/ABCB4双切口酶质粒(h) | sc-404167-NIC | h | Gene Knockout | Puromycin | 0 | ||
MDR3/ABCB4双切口酶质粒(h2) | sc-404167-NIC-2 | h | Gene Knockout | Puromycin | 0 | ||
MDR3/ABCB4 CRISPR/Cas9 KO质粒 (m) | sc-422217 | m | Gene Knockout | GFP | 0 | ||
MDR3/ABCB4 HDR 质粒 (m) | sc-422217-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
MDR3/ABCB4双切口酶质粒(m) | sc-422217-NIC | m | Gene Knockout | Puromycin | 0 | ||
MDR3/ABCB4双切口酶质粒(m2) | sc-422217-NIC-2 | m | Gene Knockout | Puromycin | 0 |
MDR CRISPR 激活产品
| Empty Table Header | 产品名称 | 目录 | Species | 应用 | 标记物 | 应用 | 排名 |
|---|---|---|---|---|---|---|---|
MDR1/ABCB1CRISPR激活质粒(h) | sc-400178-ACT | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR1/ABCB1CRISPR激活质粒(h2) | sc-400178-ACT-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR1/ABCB1慢病毒激活颗粒(h) | sc-400178-LAC | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR1/ABCB1慢病毒激活颗粒(h2) | sc-400178-LAC-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR1/ABCB1CRISPR激活质粒(m) | sc-422215-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR1/ABCB1CRISPR激活质粒(m2) | sc-422215-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR1/ABCB1慢病毒激活颗粒(m) | sc-422215-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR1/ABCB1慢病毒激活颗粒(m2) | sc-422215-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR2/ABCB4CRISPR激活质粒(m) | sc-422216-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR2/ABCB4CRISPR激活质粒(m2) | sc-422216-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR2/ABCB4慢病毒激活颗粒(m) | sc-422216-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR2/ABCB4慢病毒激活颗粒(m2) | sc-422216-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4CRISPR激活质粒(h) | sc-404167-ACT | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4CRISPR激活质粒(h2) | sc-404167-ACT-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4慢病毒激活颗粒(h) | sc-404167-LAC | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4慢病毒激活颗粒(h2) | sc-404167-LAC-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4CRISPR激活质粒(m) | sc-422217-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4CRISPR激活质粒(m2) | sc-422217-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4慢病毒激活颗粒(m) | sc-422217-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
MDR3/ABCB4慢病毒激活颗粒(m2) | sc-422217-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 |
MDR siRNA, shRNA 质粒和 shRNA 慢病毒颗粒基因沉默产品
| Empty Table Header | 产品名称 | 目录 | Species | 应用 | 标记物 | 应用 | 排名 |
|---|---|---|---|---|---|---|---|
MDR1/ABCB1 siRNA (h) | sc-29395 | h | Gene Silencing | N/A | 21 | ||
MDR1/ABCB1 shRNA 质粒 (h) | sc-29395-SH | h | Gene Silencing | Puromycin | 21 | ||
MDR1/ABCB1 shRNA (h) 慢病毒颗粒 | sc-29395-V | h | Gene Silencing | Puromycin | 21 | ||
MDR1/ABCB1 siRNA (m) | sc-35891 | m | Gene Silencing | N/A | 6 | ||
MDR1/ABCB1 shRNA 质粒 (m) | sc-35891-SH | m | Gene Silencing | Puromycin | 6 | ||
MDR1/ABCB1 shRNA (m) 慢病毒颗粒 | sc-35891-V | m | Gene Silencing | Puromycin | 6 | ||
MDR2/ABCB4 siRNA (m) | sc-37016 | m | Gene Silencing | N/A | 0 | ||
MDR2/ABCB4 shRNA 质粒 (m) | sc-37016-SH | m | Gene Silencing | Puromycin | 0 | ||
MDR2/ABCB4 shRNA (m) 慢病毒颗粒 | sc-37016-V | m | Gene Silencing | Puromycin | 0 | ||
MDR3/ABCB4 siRNA (h) | sc-37015 | h | Gene Silencing | N/A | 1 | ||
MDR3/ABCB4 shRNA 质粒 (h) | sc-37015-SH | h | Gene Silencing | Puromycin | 1 | ||
MDR3/ABCB4 shRNA (h) 慢病毒颗粒 | sc-37015-V | h | Gene Silencing | Puromycin | 1 | ||
MDR3/ABCB4 siRNA (m) | sc-37017 | m | Gene Silencing | N/A | 0 | ||
MDR3/ABCB4 shRNA 质粒 (m) | sc-37017-SH | m | Gene Silencing | Puromycin | 0 | ||
MDR3/ABCB4 shRNA (m) 慢病毒颗粒 | sc-37017-V | m | Gene Silencing | Puromycin | 0 |