Date published: 2025-9-8

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XPG 抗体 (G-4): sc-393004

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说明书
  • XPG抗体(G-4)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列887-1186位于human物种的XPG的C-terminus
  • 推荐用于 human 来源的XPG WB, IP, IF 和 ELISA检测
  • 看 XPG (8H7): sc-13563,可查看有标记的 XPG 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是XPG Antibody (G-4) for WB applications. 的首选辅助检测试剂,这些试剂现与XPG Antibody (G-4) 打包提供(请参阅下面的订购信息)。

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関連項目

已经描述了着色性干皮病的七个互补群(A-G)。着色性干皮病A组蛋白(XPA)是一种锌金属蛋白,它优先结合紫外线(UV)辐射和化学致癌物损伤的DNA。XPA是一种DNA修复酶,已被证明是核苷酸切除修复切割步骤所必需的。XPG(也称为ERCC5)是一种在DNA核苷酸切除修复中产生3'切口的核酸内切酶。哺乳动物XPG的序列与酵母RAD2相似。XPG催化中心中的保守残基对于核酸酶活性以及核苷酸切除修复功能都很重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

XPG 抗体 (G-4) 参考文献:

  1. 对柯克恩/着色性干皮病复合症的新见解:人类XPG蛋白可稳定转录因子。  |  Friedberg, EC. and Wood, RD. 2007. Mol Cell. 26: 162-4. PMID: 17466619
  2. XPG Asp1104His和XPF Arg415Gln多态性与癌症风险之间的关联:荟萃分析。  |  He, XF., et al. 2014. PLoS One. 9: e88490. PMID: 24802942
  3. XPG蛋白在胃癌的发展、进展和预后中的表达。  |  Deng, N., et al. 2014. PLoS One. 9: e108704. PMID: 25268735
  4. Xpg 限制了电离辐射后造血干细胞和祖细胞的扩增。  |  Avila, AI., et al. 2016. Nucleic Acids Res. 44: 6252-61. PMID: 27137888
  5. XPG基因多态性与胃腺癌风险。  |  Zhou, RM., et al. 2016. Genet Test Mol Biomarkers. 20: 432-7. PMID: 27228234
  6. XPG基因rs2094258多态性与胃癌风险的关系。  |  Zhang, Z., et al. 2018. J Clin Lab Anal. 32: e22564. PMID: 29732643
  7. XPG基因多态性在乳腺癌中的临床结果。  |  Malik, SS., et al. 2018. Mol Biol Rep. 45: 2369-2375. PMID: 30255276
  8. XPG rs2094258多态性与胃癌预后的关系。  |  Wang, XQ., et al. 2019. World J Gastroenterol. 25: 5152-5161. PMID: 31558863
  9. 转录物应力诱导核苷酸切除修复因子XPG的染色质重定位。  |  Scalera, C., et al. 2021. Int J Mol Sci. 22: PMID: 34205418
  10. 着色性干皮病互补群G(XPG)参与乳腺癌T辅助细胞(TH)分化的表观遗传调控。  |  Pal, R., et al. 2022. Immunobiology. 227: 152259. PMID: 36037675

订购信息

产品名称产品编号规格价格数量收藏夹

XPG 抗体 (G-4)

sc-393004
200 µg/ml
RMB2377.00

XPG (G-4): m-IgG Fc BP-HRP 套装

sc-540883
200 µg Ab; 10 µg BP
RMB2662.00

XPG (G-4): m-IgG1 BP-HRP 套装

sc-542439
200 µg Ab; 20 µg BP
RMB2662.00

What is the recommended starting dilution for Western blot for sc-393004: XPG (G-4) monoclonal antibody?

Asked by: DefinitelyNotMatt
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by from Great Western blot data of XPG expressionGreat Western blot data of XPG expression in Jurkat nuclear extract. -SCBT QC
Date published: 2014-08-27
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XPG 抗体 (G-4) is rated 5.0 out of 5 by 1.
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