Date published: 2025-9-7

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XIAP 抗体 (D-2): sc-55552

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说明书
  • XIAP抗体(D-2)是小鼠单克隆IgG2b κ, 在15篇文献中引用,规格为200 µg/ml
  • 针对氨基酸1-202,在XIAP的human起源的N-terminus处进行映射
  • 推荐用于 mouse, rat 和 human 来源的XIAP WB, IP, IF 和 ELISA检测
  • 看 XIAP (A-7): sc-55550,可查看有标记的 XIAP 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是XIAP Antibody (D-2) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与XIAP Antibody (D-2) 打包提供(请参阅下面的订购信息)。

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関連項目

杆状病毒蛋白p35可以抑制病毒诱导的无脊椎动物和哺乳动物细胞的凋亡,并可能通过破坏宿主免疫系统清除病毒感染细胞的功能来发挥作用。这至少部分是通过其抑制ICE家族丝氨酸蛋白酶的能力来阻断TNF和FAS介导的凋亡来实现的。杆状病毒p35的两个哺乳动物同源物,被称为凋亡抑制蛋白(IAP)1和2,共享一个氨基末端杆状病毒IAP重复(BIR)基序和一个羧基末端RING指结构。尽管c-IAPs不直接与TNF受体(TNF-R)结合,但它们通过与下游TNF-R效应器TRAF1和TRAF2的相互作用有效地阻断TNF介导的凋亡。IAP家族的其他成员包括XIAP和存活素。XIAP抑制活化的caspase-3,导致对FAS介导的凋亡产生抗性。存活素(也称为TIAP)在细胞周期的G2/M期表达,并与有丝分裂纺锤体的微管相关。当存活素-微管相互作用发生破坏时,可检测到caspase-3活性的增加。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

XIAP 抗体 (D-2)

sc-55552
200 µg/ml
RMB2377.00

XIAP (D-2): m-IgG Fc BP-HRP 套装

sc-537073
200 µg Ab; 10 µg BP
RMB2662.00

XIAP (D-2): m-IgGκ BP-HRP 套装

sc-534259
200 µg Ab; 40 µg BP
RMB2662.00

XIAP (D-2): m-IgG2b BP-HRP 套装

sc-549853
200 µg Ab; 10 µg BP
RMB2662.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-55552: XIAP (D-2) mouse monoclonal antibody will work?

Asked by: Randy McDonald
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 4 out of 5 by from Good specificity in WB in HeLa whole cellGood specificity in WB in HeLa whole cell lysate and mouse thymus and rat kidney tissue extracts. -SCBT QC
Date published: 2015-06-08
Rated 4 out of 5 by from Published for WB in human and mouse pancreaticPublished for WB in human and mouse pancreatic cells. -SCBT Publication Review
Date published: 2015-04-02
Rated 4 out of 5 by from Strong band in WB in human BxPCStrong band in WB in human BxPC-3 and PANC-1 cells. -SCBT Publication Review
Date published: 2015-02-22
Rated 4 out of 5 by from Positive signal in WB in human transfectedPositive signal in WB in human transfected 293T and A549 whole cell lysates. -SCBT QC
Date published: 2015-02-21
Rated 4 out of 5 by from Good publishable data in WB in human A549 cellsGood publishable data in WB in human A549 cells. -SCBT Publication Review
Date published: 2014-06-02
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XIAP 抗体 (D-2) is rated 4.0 out of 5 by 5.
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