Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

TLE1 抗体 (C-7): sc-137097

4.3(3)
寫評論提問

说明书
  • TLE1抗体(C-7)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的TLE1的氨基酸200-350
  • 推荐用于 mouse, rat 和 human 来源的TLE1 WB, IP, IF 和 ELISA检测
  • 可用于ChIP的TransCruz试剂(sc-137097 X, 200 µg/0.1 ml)
  • 看 TLE1 (F-4): sc-137098,可查看有标记的 TLE1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 1 BP-HRP">m-IgG1 BP-HRP是TLE1 Antibody (C-7) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与TLE1 Antibody (C-7) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

Notch信号通路控制着对无脊椎动物和脊椎动物中多种命运的特化至关重要的细胞间相互作用。Notch通路中的关键角色是TLE基因(代表分裂的类传导素增强子,也称为ESG,即增强子分裂的groucho),它们是人类果蝇groucho基因的同源物。Groucho是一种转录抑制因子,在神经发生、分节和性别决定中起着关键作用。TLEs与活细胞中的染色质相关联,特别是与组蛋白H3特异性关联,但不与其他核心组蛋白关联。TLE基因(TLE1、TLE2、TLE3和TLE4)的表达与正在向终末分化状态发展的未成熟上皮细胞相关,这表明它们在上皮分化过程中发挥作用。TLE1、TLE2和TLE3在宫颈鳞状上皮化生和癌中的表达升高,而TLE4在大脑中的表达最高,特别是在尾状核中。TLE1和TLE4包含SP和WD40结构域,TLE1通过这些结构域与AML1结合,抑制AML1诱导的CSF1受体反式激活。在细胞分化的早期阶段,TLE1上调,而TLE2和TLE4下调。在后期阶段,TLE2和TLE4上调,而TLE1的表达减少。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

TLE1 抗体 (C-7)

sc-137097
200 µg/ml
RMB2377.00

TLE1 (C-7): m-IgG1 BP-HRP 套装

sc-542649
200 µg Ab; 20 µg BP
RMB2662.00

TLE1 抗体 (C-7) X

sc-137097 X
200 µg/0.1 ml
RMB2377.00

What is the best protocol to run on tle-1, and also trypsin. 

Asked by: Sandi
Thank you for your question. You can find our recommended standard protocols by following this link: https://www.scbt.com/scbt/resources/protocols
Answered by: Technical Support Europe
Date published: 2020-10-16

When should the TransCruz reagent sc-137097 X be used instead of the standard form sc-137097?

Asked by: cjMara
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support
Date published: 2017-02-25
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_137097, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 106ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Positive result seen in WB using P19 wholePositive result seen in WB using P19 whole cell lysate. -SCBT QC
Date published: 2015-03-02
Rated 5 out of 5 by from Excellent immunofluorescence nuclear stainingExcellent immunofluorescence nuclear staining in formalin-fixed HepG2 cells. -SCBT QC
Date published: 2015-02-17
Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-02-08
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_137097, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 19ms
  • REVIEWS, PRODUCT
TLE1 抗体 (C-7) is rated 4.3 out of 5 by 3.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_137097, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 118ms
  • REVIEWS, PRODUCT