Date published: 2026-10-24

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TGFβ2 Antibody (B-10) - Western Blotting - Image 353249
TGFβ2 抗体 (B-10): sc-374658. HeLa (A), A549 (B), MCF7 (C) 和 NCI-H226 (D) 全细胞裂解液中 TGFβ2 表达的 Western 印迹分析.
TGFβ2 抗体 (B-10): sc-374658. HeLa (A), A549 (B), MCF7 (C) 和 NCI-H226 (D) 全细胞裂解液中 TGFβ2 表达的 Western 印迹分析.

TGFβ2 抗体 (B-10): sc-374658

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说明书
  • TGFβ2抗体(B-10)是小鼠单克隆IgG3 κ, 在6篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的TGFβ2的C-terminus的氨基酸343-377之间
  • 推荐用于 mouse, rat， human 和 avian 来源的mature and precursor forms of TGFβ2 WB, IP, IF 和 ELISA检测; 也和以下物种反应，包括： 和 equine, canine, bovine, porcine and avian
  • 看 TGFβ2 (H-6): sc-374659，可查看有标记的 TGFβ2 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG3 BP-HRP是TGFβ2 Antibody (B-10) 适用于 WB 应用。 的首选辅助检测试剂，该试剂现与TGFβ2 Antibody (B-10) 搭配使用（请参阅下面的订购信息）。
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関連項目

额外TGF抗体，包括TGF α, TGF β 1, TGF β 2, TGF β 3和TGF β

TGFβ2抗体（B-10）是一种IgG3 κ小鼠单克隆TGFβ2抗体，可通过蛋白质印迹法（WB）、免疫沉淀法（IP）、免疫荧光法（IF）以及酶联免疫吸附测定（ELISA）检测小鼠、大鼠和人类来源的成熟型和前体型TGFβ2。TGFβ2抗体（B-10）为非偶联形式的抗TGFβ2抗体。转化生长因子β（TGFβs）最初因其能够在TGFα存在下促进大鼠NRK成纤维细胞的非锚定生长而被发现。现在人们认识到，TGFβs介导胚胎发育过程中发生的许多细胞-细胞相互作用。在哺乳动物中已经鉴定出三种TGFβ。TGFβ1、TGFβ2和TGFβ3均以前体蛋白的形式合成，它们非常相似，每一种都被切割以产生一个由112个氨基酸组成的多肽，该多肽仍然与分子的潜伏部分相关联。具有生物活性的TGFβ需要单体的二聚化（通常为同源二聚体）并释放潜伏肽部分。总体而言，TGFβ3蛋白的成熟区域与TGFβ1和TGFβ2的成熟区域具有约80%的同一性。然而，它们的分子的NH2末端或前体区域仅具有27%的序列同一性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TGFβ2 抗体 (B-10) 参考文献:

  1. TGF-β2是一种运动诱导的脂质因子，可调节葡萄糖和脂肪酸代谢。  |  Takahashi, H., et al. 2019. Nat Metab. 1: 291-303. PMID: 31032475
  2. TGFβ2 诱导的脂滴形成支持酸中毒驱动的 EMT 和癌细胞的转移扩散。  |  Corbet, C., et al. 2020. Nat Commun. 11: 454. PMID: 31974393
  3. TGFβ2和TGFβ3异构体可引发纤维化疾病。  |  Sun, T., et al. 2021. Sci Transl Med. 13: PMID: 34349032
  4. 骨髓NG2+/Nestin+间充质干细胞通过TGFβ2驱动DTC休眠。  |  Nobre, AR., et al. 2021. Nat Cancer. 2: 327-339. PMID: 34993493
  5. YAP/TAZ介导TGFβ2诱导的施莱姆氏管细胞功能障碍。  |  Li, H., et al. 2022. Invest Ophthalmol Vis Sci. 63: 15. PMID: 36350617
  6. 拉伸通过间质 Gαq/11 介导的 TGFβ2 激活调节肺泡生成和稳态。  |  Goodwin, AT., et al. 2023. Development. 150: PMID: 37102682
  7. miRNA-660-3p 通过负调控 APOC1-TGFβ2 信号通路抑制胶质母细胞瘤的恶性程度  |  Yang, Z., et al. 2023. Cancer Biol Ther. 24: 2281459. PMID: 37981873
  8. MAP4K4和WT1通过协同激活宫颈癌中的ATF2-TGFβ2-Smad2/3信号通路，介导SOX6诱导的细胞衰老。  |  Zheng, H., et al. 2024. Mol Oncol. 18: 1327-1346. PMID: 38383842
  9. 肿瘤促进分子轴CircMAPKBP1/miR-17-3p/TGFβ2激活自噬通路驱动舌鳞状细胞癌顺铂化疗耐药  |  Xie, S., et al. 2024. Cancer Lett. 604: 217230. PMID: 39276917
  10. TGFβ2驱动的铁蛋白降解和随后的铁突变是绝经后唾液腺功能障碍的基础  |  Oh, SJ., et al. 2024. Adv Sci (Weinh). 11: e2400660. PMID: 39481440

订购信息

产品名称产品编号规格价格数量收藏夹

TGFβ2 抗体 (B-10)

sc-374658
200 µg/ml
CNY2422.00

TGFβ2 (B-10): m-IgG3 BP-HRP 套装

sc-550582
200 µg Ab; 40 µg BP
CNY2715.00

TGFβ2 (B-10) 中和勝肽

sc-374658 P
100 µg/0.5 ml
CNY519.00

How to receive FREE 10 µg sample of TGFβ2 (B-10): sc-374658 to check in Western blot?

Asked by: Amandab
Thank you for your question. To request a sample please contact Technical service . Please call 800-457-3801 or email [email protected].
Answered by: BlakeJ
Date published: 2025-06-12

What application is the blocking peptide sc-374658 P appropriate for?

Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by HPHlab from Good functioningWe bought this antibody a month ago. We used it for the detection of mature form of TGFb2 of human by Western Blotting with a diluition 1:500, it gave good detection of both recombinant protein and its reference standard.
Date published: 2023-11-10
Rated 5 out of 5 by Rosa from Very specific.This antibody was used at 1:1000 dilutionon on blots loaded with 30 ug of cell protein extracts, it worked great, no extra bands.
Date published: 2021-02-25
Rated 5 out of 5 by TinTin from Excellent choice for TGFβ2!Looking for a reliable TGF beta 2 antibody? This is a great one, especially for Western blot. Strong and specific, it's a good choice.
Date published: 2017-02-03
Rated 5 out of 5 by TS from Good WB antibody in human recombinant TGFGood WB antibody in human recombinant TGF 2 fusion protein. -SCBT QC
Date published: 2013-02-04
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TGFβ2 抗体 (B-10) is rated 4.8 out of 5 by 4.
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