Date published: 2025-9-6
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TGFα Antibody (D-6) - Immunohistochemistry - Image 286452
TGFa (D-6): sc-374433. 福尔马林固定, 石蜡包埋的人肾组织的免疫过氧化物酶染色, 显示肾小管细胞的胞浆染色.
TGFa (D-6): sc-374433. 福尔马林固定, 石蜡包埋的人肾组织的免疫过氧化物酶染色, 显示肾小管细胞的胞浆染色.

TGFα 抗体 (D-6): sc-374433

4.4(10)
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说明书
  • TGF alpha 抗体 D-6 是小鼠单克隆 IgG1 κ，TGFα抗体, 在8篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的TGFå的C-terminus的氨基酸63-89之间
  • TGF alpha 抗体 (D-6) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 presursor and mature TGFα and BTC; 也和以下物种反应，包括： 和 equine, canine, bovine and porcine
  • 抗TGF alpha抗体（D-6）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取TGFα (D-6): sc-374433的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 TGFα 抗体 (D-6) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与TGFα 抗体 (D-6) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 TGF 抗体 包括 TGF α, TGF β 1, TGF β 2, TGF β 3和TGF β

TGFα抗体（D-6）是一种IgG1κ小鼠单克隆TGFα抗体（也称为转化生长因子α抗体或TGF-α抗体），可通过WB、IP、IF、IHC（P）和ELISA检测小鼠、大鼠和人类来源的TGFα蛋白。TGFα抗体（D-6）既可以作为非偶联的抗TGFα抗体形式，也可以作为多种偶联形式的抗TGFα抗体，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。转化生长因子α（TGFα）是一种酸性和热稳定的50个氨基酸蛋白质，最初发现于啮齿动物和人类。TGFα在氨基酸水平上与表皮生长因子（EGF）有33%的同源性。TGFα与EGF受体结合，介导受体的酪氨酸磷酸化，并在转化生长因子β存在的情况下促进正常大鼠成纤维细胞在软琼脂中的非锚定生长。TGFa由多种转化细胞和肿瘤、胚胎细胞和一些正常成人细胞分泌。在癌症患者的尿液中发现了转化生长因子α的生物活性。有人认为，它可能作为自分泌生长因子，诱导或维持恶性肿瘤。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TGFα 抗体 (D-6) 参考文献:

  1. 人类转化生长因子α特异性单克隆抗体的制备和特性分析。  |  Sorvillo, JM., et al. 1990. Oncogene. 5: 377-86. PMID: 1690379
  2. 表皮生长因子相关蛋白在人类结直肠肿瘤中的差异表达。  |  Ciardiello, F., et al. 1991. Proc Natl Acad Sci U S A. 88: 7792-6. PMID: 1715580
  3. 转化生长因子α参与鸟类繁殖的光周期调节。  |  Takagi, T., et al. 2007. Endocrinology. 148: 2788-92. PMID: 17363456
  4. 大鼠肝脏在亚硝胺诱导的肝癌发生过程中 ErbB 受体蛋白和 TGF-α 的表达。  |  Lee, TY., et al. 2007. Korean J Hepatol. 13: 70-80. PMID: 17380077
  5. 培养中的未转化牛垂体前叶细胞分泌的α-转化生长因子。I. 从条件培养基中提纯。  |  Samsoondar, J., et al. 1986. J Biol Chem. 261: 14408-13. PMID: 3464597
  6. 转化生长因子-α：结构和生物活性。  |  Derynck, R. 1986. J Cell Biochem. 32: 293-304. PMID: 3543030
  7. 人类转化生长因子诱导 EGF 受体的酪氨酸磷酸化。  |  Reynolds, FH., et al. 1981. Nature. 292: 259-62. PMID: 6265789
  8. 由逆转录病毒转化的啮齿动物成纤维细胞和人类黑色素瘤细胞产生的转化生长因子：与表皮生长因子的氨基酸序列同源性。  |  Marquardt, H., et al. 1983. Proc Natl Acad Sci U S A. 80: 4684-8. PMID: 6308641
  9. 与正常人相比，癌症患者尿液中转化生长因子活性的高效液相色谱模式截然不同。  |  Kimball, ES., et al. 1984. Cancer Res. 44: 3613-9. PMID: 6331653

订购信息

产品名称产品编号规格价格数量收藏夹

TGFα 抗体 (D-6)

sc-374433
200 µg/ml
RMB2377.00

TGFα (D-6): m-IgG Fc BP-HRP 套装

sc-529744
200 µg Ab; 10 µg BP
RMB2662.00

TGFα (D-6): m-IgGκ BP-HRP 套装

sc-522737
200 µg Ab, 40 µg BP
RMB2662.00

TGFα (D-6): m-IgG1 BP-HRP 套装

sc-543666
200 µg Ab; 20 µg BP
RMB2662.00

TGFα 抗体 (D-6) AC

sc-374433 AC
500 µg/ml, 25% agarose
RMB3129.00

TGFα 抗体 (D-6) HRP

sc-374433 HRP
200 µg/ml
RMB2377.00

TGFα 抗体 (D-6) FITC

sc-374433 FITC
200 µg/ml
RMB2482.00

TGFα 抗体 (D-6) PE

sc-374433 PE
200 µg/ml
RMB2580.00

TGFα 抗体 (D-6) Alexa Fluor® 488

sc-374433 AF488
200 µg/ml
RMB2685.00

TGFα 抗体 (D-6) Alexa Fluor® 546

sc-374433 AF546
200 µg/ml
RMB2685.00

TGFα 抗体 (D-6) Alexa Fluor® 594

sc-374433 AF594
200 µg/ml
RMB2685.00

TGFα 抗体 (D-6) Alexa Fluor® 647

sc-374433 AF647
200 µg/ml
RMB2685.00

TGFα 抗体 (D-6) Alexa Fluor® 680

sc-374433 AF680
200 µg/ml
RMB2685.00

TGFα 抗体 (D-6) Alexa Fluor® 790

sc-374433 AF790
200 µg/ml
RMB2685.00

TGFα (D-6) 中和勝肽

sc-374433 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-374433 P appropriate for?

Asked by: jenniferc
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Buon funzionamentoHo testato questo anticorpo nei mesi scorsi e si vede una banda all'altezza desiderata
Date published: 2022-02-03
Rated 1 out of 5 by from Does not workWe tested this antibody in IP and western. Unfortunately, it does not work at all. We used as control other antibodies anti-TGF-a that we created and published. SCBT should solve this.
Date published: 2018-11-28
Rated 4 out of 5 by from The product is good.This antibody is a small molecule,and it's not easy for a novice to get a good WB result.So even though I didn't get the wanted results,I still want to give it a good comment.Maybe I should learn more to improve my experimental skills.
Date published: 2017-07-11
Rated 5 out of 5 by from this antibody in WBApplications used: western blot Cell Line, human good Antibody
Date published: 2017-05-16
Rated 5 out of 5 by from Excellent!This antibody works great in western blot analysis of human recombinant TGFα fusion protein.
Date published: 2017-01-20
Rated 5 out of 5 by from Produced exceptional immunoperoxidase cytoplasmicProduced exceptional immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human kidney tissue. -SCBT QC
Date published: 2015-05-17
Rated 5 out of 5 by from Publishable WB data in human OsteosarcomaPublishable WB data in human Osteosarcoma cell line. -SCBT Publication Review
Date published: 2015-04-22
Rated 5 out of 5 by from Published data for WB in human bladder cellsPublished data for WB in human bladder cells. -SCBT Publication Review
Date published: 2015-04-22
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TGFα 抗体 (D-6) is rated 4.4 out of 5 by 10.
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