Date published: 2026-10-24

1-800-457-3801

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
TGFα Antibody (134 A) - Western Blotting - Image 43723
TGFα (134 A): sc-36. A-431 (A) 和 SW480 (B) 全细胞裂解液中 TGFα 表达的 Western 印迹分析.
TGFα Antibody (134 A) - Western Blotting - Image 43723
TGFα (134 A): sc-36. A-431 (A) 和 SW480 (B) 全细胞裂解液中 TGFα 表达的 Western 印迹分析.
TGFα Antibody (134 A) - Immunofluorescence - Image 2459
TGFα (134 A): sc-36. 甲醇固定的 A-431 细胞免疫荧光染色显示膜定位.
TGFα Antibody (134 A) - Western Blotting - Image 2466
TGFα (134 A): sc-36. 人重组 TGFα 的 Western 印迹分析.
TGFα (134 A): sc-36. A-431 (A) 和 SW480 (B) 全细胞裂解液中 TGFα 表达的 Western 印迹分析.

TGFα 抗体 (134 A): sc-36

4.3(7)
寫評論提問
说明书
  • TGF alpha 抗体 134 A 是小鼠单克隆 IgG1, 在38篇文献中引用，提供 100 µg/ml
  • 针对human重组TGFα蛋白的抗原性氨基酸
  • 推荐用于 mouse, rat 和 human 来源的precursor and mature TGFα WB, IP 和 IF检测
  • 目前，我们还没有完成TGFα 抗体 (134 A)的首选二抗检测试剂的鉴定。这项工作正在进行中。
Gene Editing Promo Banner

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

附加TGF抗体，包括TGF α, TGF β 1, TGF β 2, TGF β 3和TGF β

TGFα抗体（134 A）是一种小鼠单克隆IgG1抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）和免疫荧光（IF）等方法检测小鼠、大鼠和人类样本中的转化生长因子-α（TGFα）。TGFα是一种关键的50个氨基酸蛋白，在细胞信号传导和生长调节中发挥着重要作用，特别是在癌症方面。TGFα与表皮生长因子受体（EGFR）结合，激活下游信号通路，促进细胞增殖和存活。这种相互作用有助于各种恶性肿瘤的发展和进展，使TGFα成为治疗干预的潜在目标。TGFα由转化细胞、肿瘤和一些正常的成人细胞分泌，表明它参与了生理和病理过程。癌症患者尿液中的TGFα生物活性凸显了其作为恶性肿瘤生物标志物的相关性，表明其作为支持肿瘤生长和维持的自体生长因子的功能。TGFα介导重要的细胞功能，是癌症生物学和治疗策略研究人员的重要蛋白质。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TGFα 抗体 (134 A) 参考文献:

  1. TGFα在脑膜瘤中的表达。  |  Halper, J., et al. 1999. J Neurooncol. 45: 127-34. PMID: 10778728
  2. 转化生长因子α：一种可能具有生物学意义的运动神经元存活促进因子。  |  Boillée, S., et al. 2001. J Neurosci. 21: 7079-88. PMID: 11549718
  3. 人类角质形成细胞中TGF-α表达的调节：PKC依赖性和非依赖性途径。  |  Klein, SB., et al. 1992. J Cell Physiol. 151: 326-36. PMID: 1572907
  4. 激活蛋白2α介导继发性甲状旁腺功能亢进症中甲状旁腺TGF-α的自我诱导。  |  Arcidiacono, MV., et al. 2008. J Am Soc Nephrol. 19: 1919-28. PMID: 18579641
  5. 血清中TGF-α含量高预示着HER2阳性乳腺癌对拉帕替尼和卡培他滨的反应不佳。  |  Rhee, J., et al. 2011. Breast Cancer Res Treat. 125: 107-14. PMID: 20936340
  6. TGFα-PE38可增强细胞毒性T淋巴细胞对乳腺癌细胞的杀伤作用。  |  Wright, SE., et al. 2014. Oncol Lett. 7: 2113-2117. PMID: 24932299
  7. 跨膜TGF-α前体可激活EGF/TGF-α受体。  |  Brachmann, R., et al. 1989. Cell. 56: 691-700. PMID: 2645058
  8. TGFα在髓样恶性肿瘤中的表达。  |  Kavanagh, S., et al. 2016. J Clin Pathol. 69: 543-6. PMID: 26984929
  9. TGFα可保护少突胶质细胞系细胞，并改善脑缺血后的白质完整性。  |  Dai, X., et al. 2020. J Cereb Blood Flow Metab. 40: 639-655. PMID: 30834805
  10. 正常和病理大脑中的转化生长因子-α（TGF-α）和表皮生长因子受体（EGF-R）免疫反应。  |  Ferrer, I., et al. 1996. Prog Neurobiol. 49: 99-123. PMID: 8844822

订购信息

产品名称产品编号规格价格数量收藏夹

TGFα 抗体 (134 A)

sc-36
100 µg/ml
CNY2422.00

When should the TransCruz reagent sc-36 X be used instead of the standard form sc-36?

Asked by: Dr Ninau Qelp
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_10, d_24, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_36, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 107ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by TS from Produced robust immunofluorescence membraneProduced robust immunofluorescence membrane staining in methanol-fixed A-431 cells. -SCBT QC
Date published: 2015-04-04
Rated 4 out of 5 by LF from Good IP data obtained using mouse C3H10T1/2 cellsGood IP data obtained using mouse C3H10T1/2 cells. -SCBT Publication Review
Date published: 2015-03-15
Rated 5 out of 5 by SH from Publishable data using rat gastric mucosalPublishable data using rat gastric mucosal cells in co-IP. -SCBT Publication Review
Date published: 2015-03-12
Rated 5 out of 5 by LF from It has been reported that mouse salivaryIt has been reported that mouse salivary glands was analyzed successfully by IF. -SCBT Publication Review
Date published: 2015-03-12
Rated 3 out of 5 by HF from Large bulbous band observed by Western BlotLarge bulbous band observed by Western Blot using human recombinant TGF protein. Otherwise, clean clear background. -SCBT QC
Date published: 2015-02-03
Rated 5 out of 5 by SS from Several researchers have published data bySeveral researchers have published data by WB using human HaCaT cells and rat Leydig cells. Also successful in analyzing mouse liver extracts. -SCBT Publication Review
Date published: 2015-01-26
Rated 4 out of 5 by MS from Various publications describe the use ofVarious publications describe the use of this antibody in IHC using human prostate tissue, mouse and rat retina tissue. -SCBT Publication Review
Date published: 2015-01-06
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_36, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
TGFα抗体 (134 A) is rated 4.3 out of 5 by 7.
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_36, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 92ms
  • REVIEWS, PRODUCT
1-800-457-3801
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打1-800-457-3801联系我们。
版权所有© 2007-2026 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。