Date published: 2025-9-7

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Tau 抗体 (TAU-5): sc-58860

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说明书
  • Tau抗体(TAU-5)是小鼠单克隆IgG1 κ, 在35篇文献中引用,规格为200 µg/ml
  • 针对纯化的Tau bovine 起源
  • 推荐用于 mouse, rat, human 和 bovine 来源的both phosphorylated and non-phosphorylated Tau proteins WB, IP, IF 和 IHC(P)检测; 不会与 tubulin or other microtubule associated proteins产生交联反应
  • 看 Tau (Tau 46): sc-32274,可查看有标记的 Tau 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 关于如何获取Tau (TAU-5): sc-58860免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 Tau 抗体 (TAU-5) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Tau 抗体 (TAU-5) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Tau抗体(TAU-5)是一种小鼠单克隆IgG1 kappa轻链抗体,用于识别纯化的牛源性Tau蛋白,特异性靶向人类Tau的C端。Tau单克隆抗体(TAU-5)能够可靠地检测小鼠、大鼠、人类和牛源的磷酸化和非磷酸化Tau蛋白,可用于多种应用,包括蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和石蜡包埋切片免疫组织化学(IHCP)。Tau,也称为MAPT(微管相关蛋白Tau)或TAU,是一种主要由758个氨基酸组成的蛋白质,主要存在于神经细胞质、细胞骨架和细胞膜中。Tau的主要功能是稳定微管,而微管对于维持神经元的结构完整性和促进细胞内运输至关重要。通过促进微管的组装和稳定,Tau在维持神经元的极性和支持细胞骨架可塑性方面发挥着关键作用,而神经元的极性和可塑性对于神经元的正常功能和连接至关重要。Tau(TAU-5)抗体存在多种可变剪接的同工型,在神经元的健康和适应性方面发挥着不同的作用。Tau经历多种翻译后修饰,包括磷酸化、多泛素化和糖化,这些修饰可调节其活性和降解,确保细胞骨架的动态变化。Tau功能和结构的失调与多种神经退行性疾病有关,如阿尔茨海默氏病、苍白球-桥脑-黑质变性(PPND)、皮质基底变性(CBD)和进行性核上性麻痹(PSP),这凸显了维持神经元完整性和在疾病病理学中发挥作用的重要性。Tau(TAU-5)单克隆抗体以非结合形式提供,为研究人员提供了研究Tau在细胞过程和神经退行性疾病中作用的可靠工具。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Tau 抗体 (TAU-5)

sc-58860
200 µg/ml
RMB2377.00

Tau (TAU-5): m-IgG Fc BP-HRP 套装

sc-526916
200 µg Ab; 10 µg BP
RMB2662.00

Tau (TAU-5): m-IgG1 BP-HRP 套装

sc-532289
200 µg Ab; 20 µg BP
RMB2662.00

Is there any data using this antibody as a capture in an ELISA?

Asked by: Paul
Thank you for your question. Tau Antibody is recommended for WB, IP, IF and IHC. We do not recommend the antibody for Sandwich ELISA.
Answered by: BlakeJ
Date published: 2025-09-01

Does this tau5 antibody work for immunoprecipitation in cell or mouse brain lysate?

Asked by: Jiyoen
Thank you for your question. This antibody is fine for immunoprecipitation on mouse brain samples. Please contact Technical Service by phone, (800)-457-3801 option 2, email <[email protected]>, or by live chat directly on our website, www.scbt.com if you have any further questions.
Answered by: Tech Service
Date published: 2017-08-31

Is Tau (TAU-5): sc-58860 available directly conjugated to HRP?

Asked by: jenniferc
Thank you for your question. All requests for directly conjugated versions of this antibody should be directed to our Special Orders team at [email protected] Alternatively, consider using Tau (Tau 46): sc-32274, which is available conjugated to agarose, HRP, FITC, PE, and more. (https://www.scbt.com/scbt/product/tau-antibody-tau-46)
Answered by: Technical Support 5
Date published: 2017-01-19
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Rated 4 out of 5 by from works best at 1:50used for western blotting using milk blocking buffer; primary antibody incubation overnight at 4 degree (1:50) 1hr RT secondary incubation at 1:2000 dilution
Date published: 2024-01-02
Rated 5 out of 5 by from 效果不错我买了这个产品,效果不错,希望在今后能够继续好用,在今后能够更好的帮助我的实验,为我的论文地基做好贡献。
Date published: 2023-07-23
Rated 5 out of 5 by from ICCI tested a this for immunocyto staining and it worked very well. I plan to order more for general western blotting as I'm very content with the results
Date published: 2018-08-10
Rated 5 out of 5 by from Excellent antibodyI received a TAU-5 antibody and performed Western Blotting using brain lysates. I used 1:1000 dilution and got a very good signal.
Date published: 2018-06-19
Rated 5 out of 5 by from Strong signal, clean bandsI received a free sample of this antibody and it worked very well even at very low concentrations.
Date published: 2018-01-24
Rated 5 out of 5 by from Great WBStrong western blot data; clear signal, low background
Date published: 2017-02-02
Rated 5 out of 5 by from Excellent!This antibody works great in western blot analysis of Tau expression in mouse brain tissue extract.
Date published: 2017-01-11
Rated 4 out of 5 by from Robust band seen in WB using mouse brainRobust band seen in WB using mouse brain tissue extract. -SCBT QC
Date published: 2015-02-03
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Tau 抗体 (TAU-5) is rated 4.7 out of 5 by 9.
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