Date published: 2025-9-7

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survivin 抗体 (8E2): sc-47750

4.3(4)
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说明书
  • survivin抗体(8E2)是小鼠单克隆IgG1 κ, 在8篇文献中引用,规格为200 µg/ml
  • 针对全长human survivin
  • 推荐用于 mouse, rat 和 human 来源的survivin WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 survivin (D-8): sc-17779,可查看有标记的 survivin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 survivin 抗体 (8E2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与survivin 抗体 (8E2) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

杆状病毒蛋白p35抑制由病毒引起的无脊椎动物和哺乳动物细胞的凋亡,并且可能起损害由宿主免疫系统清除病毒感染细胞的作用。这至少部分地通过p35抑制ICE丝氨酸蛋白酶家族的能力来实现,从而阻断TNF和FAS介导的凋亡。杆状病毒p35的两个哺乳动物同源物,被称为凋亡抑制蛋白(IAP)1和2,共享一个氨基末端杆状病毒IAP重复(BIR)基序和一个羧基末端RING指。尽管c-IAPs不直接与TNF受体(TNF-R)相关,但它们通过与下游TNF-R效应物TRAF1和TRAF2的相互作用,有效地阻断TNF介导的凋亡。IAP家族的其他成员包括ILP(用于IAP样蛋白)和survivin。ILP抑制活化的caspase-3,导致对FAS介导的凋亡的抗性。Survivin(也称为TIAP)在细胞周期的G2/M期表达,并与有丝分裂纺锤体的微管相关。当survivin-微管相互作用发生破坏时,检测到caspase-3活性增加。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

survivin 抗体 (8E2)

sc-47750
200 µg/ml
RMB2377.00

survivin (8E2): m-IgG Fc BP-HRP 套装

sc-536807
200 µg Ab; 10 µg BP
RMB2662.00

survivin (8E2): m-IgGκ BP-HRP 套装

sc-533972
200 µg Ab; 40 µg BP
RMB2662.00

survivin (8E2): m-IgG1 BP-HRP 套装

sc-544830
200 µg Ab; 20 µg BP
RMB2662.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with survivin (8E2): sc-47750 monoclonal antibody?

Asked by: DefinitelyNotMatt
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from we usually this antibodywe follow the WB protocol of santa, detect Hela cell use this antibody, got strong band.
Date published: 2017-06-11
Rated 5 out of 5 by from Helpfulsurvivin antibody provides clear and specific results. Strong single band in WB in mouse peritoneal macrophages.Very satisfied, very helpful to us.
Date published: 2017-02-11
Rated 5 out of 5 by from Clean WBClean WB with strong band using human recombinant survivin fusion protein.
Date published: 2017-01-15
Rated 2 out of 5 by from Works with human recombinant survivin fusionWorks with human recombinant survivin fusion protein by WB with some background. -SCBT QC
Date published: 2014-03-21
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survivin 抗体 (8E2) is rated 4.3 out of 5 by 4.
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