Date published: 2025-9-11

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Suppressor of Hairless 抗体 (C-9): sc-398453

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说明书
  • Suppressor of Hairless 抗体 C-9 是小鼠单克隆 IgG2a κ,Suppressor of Hairless抗体, 在5篇文献中引用,规格为200 µg/ml
  • 针对氨基酸的 259-594 of Suppressor of Hairless of Hairless of Drosophila melanogaster origin
  • Suppressor of Hairless 抗体 (C-9) 推荐用于WB, IP, IF 和 ELISA,检测d 来源的 Suppressor of Hairless
  • 抗Suppressor of Hairless抗体(C-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Suppressor of Hairless (C-9): sc-398453免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Suppressor of Hairless Antibody (C-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Suppressor of Hairless Antibody (C-9) 打包提供(请参阅下面的订购信息)。

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Suppressor of Hairless抗体(C-9)是一种IgG2a κ小鼠单克隆Suppressor of Hairless抗体(也称为Suppressor of Hairless抗体),可通过WB、IP、IF和ELISA检测黑腹果蝇来源的Suppressor of Hairless蛋白。Suppressor of Hairless抗体(C-9)既有非偶联的抗Suppressor of Hairless抗体形式,也有多种偶联形式的抗Suppressor of Hairless抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。黑腹果蝇已被证明是研究高等真核生物发育和细胞过程的有效模型。在超过1.2亿个碱基对的常染色质中,已阐明了大约13,600个基因,它们分布在2、3、4、X和Y染色体上,其中Y染色体主要是异染色质的。果蝇基因可以根据其编码的蛋白质类型进行分类,并由六个主要分类代表,包括细胞内信号蛋白、跨膜蛋白、RNA结合蛋白、分泌因子、转录调节因子(基本螺旋-环-螺旋、含同源结构域、含锌指和染色质相关)或其他功能蛋白。在这些蛋白质中,Suppressor of Hairless,Su(H)是一种与活化的Notch受体相互作用的细胞质蛋白,随后定位于细胞核。核Su(H)作为转录因子,靶向Enhancer of split复合体并引发神经源性信号。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Suppressor of Hairless 抗体 (C-9) 参考文献:

  1. 黑腹果蝇的基因组序列。  |  Adams, MD., et al. 2000. Science. 287: 2185-95. PMID: 10731132
  2. 在果蝇中,无毛抑制因子的转录抑制涉及无毛-DCtBP 复合物的结合。  |  Morel, V., et al. 2001. Curr Biol. 11: 789-92. PMID: 11378391
  3. 在果蝇刚毛感觉器官前体细胞的发育过程中,无毛抑制因子的功能与 Notch 无关。  |  Koelzer, S. and Klein, T. 2003. Development. 130: 1973-88. PMID: 12642500
  4. 通过一种涉及无毛稳定性抑制因子和羧基末端截短的 Notch 的新机制来调节 Notch 信号传导。  |  Wesley, CS. and Mok, LP. 2003. Mol Cell Biol. 23: 5581-93. PMID: 12897132
  5. 在果蝇notch细胞内结构域中鉴定出两个无毛抑制蛋白的结合区域。  |  Le Gall, M. and Giniger, E. 2004. J Biol Chem. 279: 29418-26. PMID: 15123610
  6. 果蝇deltex介导不依赖毛发和晚期内体激活Notch信号的抑制因子。  |  Hori, K., et al. 2004. Development. 131: 5527-37. PMID: 15496440
  7. 果蝇的长期记忆形成需要无毛抑制因子。  |  Song, Q., et al. 2009. J Neurogenet. 23: 405-11. PMID: 19863271
  8. Insensitive 是无毛发抑制因子的核心抑制因子,在神经发育过程中调节 Notch 信号。  |  Duan, H., et al. 2011. EMBO J. 30: 3120-33. PMID: 21765394
  9. 无毛结合缺陷抑制剂等位基因显示,Su(H)蛋白水平取决于与无毛形成的复合物。  |  Praxenthaler, H., et al. 2017. PLoS Genet. 13: e1006774. PMID: 28475577
  10. 无毛抑制因子的磷酸化阻碍了其 DNA 结合活性。  |  Nagel, AC., et al. 2017. Sci Rep. 7: 11820. PMID: 28928428
  11. 缺乏共抑制因子结合的新型无毛等位基因的复杂遗传相互作用。  |  Preiss, A., et al. 2018. PLoS One. 13: e0193956. PMID: 29509808
  12. Notch信号传导过程中果蝇感觉器细胞中无毛抑制因子的亚细胞定位  |  Gho, M., et al. 1996. Development. 122: 1673-82. PMID: 8674407

订购信息

产品名称产品编号规格价格数量收藏夹

Suppressor of Hairless 抗体 (C-9)

sc-398453
200 µg/ml
RMB2377.00

Suppressor of Hairless (C-9): m-IgG Fc BP-HRP 套装

sc-530803
200 µg Ab; 10 µg BP
RMB2662.00

Suppressor of Hairless (C-9): m-IgGκ BP-HRP 套装

sc-524347
200 µg Ab, 40 µg BP
RMB2662.00

Suppressor of Hairless (C-9): m-IgG2a BP-HRP 套装

sc-547593
200 µg Ab; 10 µg BP
RMB2662.00

Suppressor of Hairless 抗体 (C-9) AC

sc-398453 AC
500 µg/ml, 25% agarose
RMB3129.00

Suppressor of Hairless 抗体 (C-9) HRP

sc-398453 HRP
200 µg/ml
RMB2377.00

Suppressor of Hairless 抗体 (C-9) FITC

sc-398453 FITC
200 µg/ml
RMB2482.00

Suppressor of Hairless 抗体 (C-9) PE

sc-398453 PE
200 µg/ml
RMB2580.00

Suppressor of Hairless 抗体 (C-9) Alexa Fluor® 488

sc-398453 AF488
200 µg/ml
RMB2685.00

Suppressor of Hairless 抗体 (C-9) Alexa Fluor® 546

sc-398453 AF546
200 µg/ml
RMB2685.00

Suppressor of Hairless 抗体 (C-9) Alexa Fluor® 594

sc-398453 AF594
200 µg/ml
RMB2685.00

Suppressor of Hairless 抗体 (C-9) Alexa Fluor® 647

sc-398453 AF647
200 µg/ml
RMB2685.00

Suppressor of Hairless 抗体 (C-9) Alexa Fluor® 680

sc-398453 AF680
200 µg/ml
RMB2685.00

Suppressor of Hairless 抗体 (C-9) Alexa Fluor® 790

sc-398453 AF790
200 µg/ml
RMB2685.00

What is the recommended starting dilution for Western blot for sc-398453: Suppressor of Hairless (C-9) monoclonal antibody?

Asked by: DefinitelyNotMatt
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by from Very good Western blot data of SuppressorVery good Western blot data of Suppressor of Hairless expression in Schneider's Drosophila Line 2 whole cell lysate. -SCBT QC
Date published: 2014-01-18
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Suppressor of Hairless 抗体 (C-9) is rated 5.0 out of 5 by 1.
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