Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

SULT1 抗体 (B-4): sc-376159

5.0(4)
寫評論提問

说明书
  • SULT1 抗体 B-4 是小鼠单克隆 IgG1 (kappa轻链),SULT1抗体,规格为200 µg/ml
  • 免疫原氨基酸序列51-105位于human物种的SULT1A1的内部区域内
  • SULT1 抗体 (B-4) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 SULT1A1, SULT1A2 and SULT1A3; 可能与 other SULT family members产生交联反应
  • 抗SULT1抗体(B-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取SULT1 (B-4): sc-376159免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 SULT1 抗体 (B-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与SULT1 抗体 (B-4) 组合成套装提供。 (请参阅下面的订购信息)。

    快捷链接

    関連項目

    SULT1抗体(B-4)是一种IgG1κ型小鼠单克隆SULT1抗体(也称为SULT1抗体),可通过WB, IP, IF, IHC(P) 和 ELISA检测小鼠、大鼠和人类的SULT1蛋白。SULT1抗体(B-4)既可作为非偶联抗SULT1抗体,也可作为多种偶联形式的抗SULT1抗体,包括琼脂糖、辣根过氧化物酶、藻红蛋白、异硫氰酸荧光素和多种Alexa Fluor®偶联物。可溶性磺基转移酶通过催化这些物质的硫酸盐结合,有助于消除异种生物、激活前致癌物和调节激素。构成这一超家族的三个组成员对某些底物化合物表现出选择性。SULT1磺基转移酶表现出致癌杂环胺的N-磺化活性,并对苯酚有选择性,而SULT2酶则更喜欢羟基类固醇,SULT3家族成员对N-取代芳基和脂环族化合物具有选择性。SULT1的高活性与对许多导致结直肠癌的致癌物的增强保护有关。SULT1A1等位基因在老年人中的活性更高,这可能是由于SULT1对衰老带来的细胞和组织损伤提供了保护。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    SULT1 抗体 (B-4) 参考文献:

    1. 催化杂环胺类硫化的转磺酶。  |  Yamazoe, Y., et al. 1999. Cancer Lett. 143: 103-7. PMID: 10503886
    2. 人类磺基转移酶 1A1 和 1A2 的功能性基因多态性之间的关联。  |  Engelke, CE., et al. 2000. Pharmacogenetics. 10: 163-9. PMID: 10762004
    3. 人类 SULT1B1 基因的结构和定位:与 SULT1E1 和 SULT1D 伪基因的邻近。  |  Meinl, W. and Glatt, H. 2001. Biochem Biophys Res Commun. 288: 855-62. PMID: 11688987
    4. 转磺酸酶 1A2*2 是早发乳腺癌的风险因素。  |  Hou, MF., et al. 2002. Int J Mol Med. 10: 609-12. PMID: 12373301
    5. 人类磺基转移酶对阿朴吗啡的硫化作用:多态酚磺基转移酶 SULT1A1 发挥重要作用的证据。  |  Thomas, NL. and Coughtrie, MW. 2003. Xenobiotica. 33: 1139-48. PMID: 14660177
    6. 人类磺基转移酶 SULT1A1 基因受 Sp1 和 GA 结合蛋白的协同调控。  |  Hempel, N., et al. 2004. Mol Pharmacol. 66: 1690-701. PMID: 15383623
    7. 人类肝脏中 SULT1A1 的表型-基因型关系以及 SULT1A1 抑制剂槲皮素 IC50 的变化。  |  Rossi, AM., et al. 2004. Int J Clin Pharmacol Ther. 42: 561-7. PMID: 15516026
    8. 肝脏中的芳胺活化磺基转移酶  |  Nagata, K., et al. 1997. Mutat Res. 376: 267-72. PMID: 9202764

    订购信息

    产品名称产品编号规格价格数量收藏夹

    SULT1 抗体 (B-4)

    sc-376159
    200 µg/ml
    $316.00

    SULT1 (B-4): m-IgG Fc BP-HRP 套装

    sc-529827
    200 µg Ab; 10 µg BP
    $354.00

    SULT1 (B-4): m-IgGκ BP-HRP 套装

    sc-522855
    200 µg Ab, 40 µg BP
    $354.00

    SULT1 (B-4): m-IgG1 BP-HRP 套装

    sc-543710
    200 µg Ab; 20 µg BP
    $354.00

    SULT1 抗体 (B-4) AC

    sc-376159 AC
    500 µg/ml, 25% agarose
    $416.00

    SULT1 抗体 (B-4) HRP

    sc-376159 HRP
    200 µg/ml
    $316.00

    SULT1 抗体 (B-4) FITC

    sc-376159 FITC
    200 µg/ml
    $330.00

    SULT1 抗体 (B-4) PE

    sc-376159 PE
    200 µg/ml
    $343.00

    SULT1 抗体 (B-4) Alexa Fluor® 488

    sc-376159 AF488
    200 µg/ml
    $357.00

    SULT1 抗体 (B-4) Alexa Fluor® 546

    sc-376159 AF546
    200 µg/ml
    $357.00

    SULT1 抗体 (B-4) Alexa Fluor® 594

    sc-376159 AF594
    200 µg/ml
    $357.00

    SULT1 抗体 (B-4) Alexa Fluor® 647

    sc-376159 AF647
    200 µg/ml
    $357.00

    SULT1 抗体 (B-4) Alexa Fluor® 680

    sc-376159 AF680
    200 µg/ml
    $357.00

    SULT1 抗体 (B-4) Alexa Fluor® 790

    sc-376159 AF790
    200 µg/ml
    $357.00

    Can SULT1 (B-4): sc-376159 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: DefinitelyNotMatt
    Thank you for your question. Yes, SULT1 (B-4): sc-376159 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2025, m_9, d_6, h_5CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_zh_CN, sid_376159, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 106ms
    • QUESTIONS, PRODUCT
    Rated 5 out of 5 by from Works great for western blot!Works well for western experiments with lysates from human-derived cancer cell lines and mouse tissue samples. Used 1:200 and got a good signal! Will use again!
    Date published: 2018-03-22
    Rated 5 out of 5 by from Works well for western blotProbed this antibody at 1/1000 dilution for 2 hrs, the signal was a bit weak, but because I used the kappa-binding-HRP as secondary, I was able to take a long exposure and detected the SULT1 exactly where I expected. Overall a very good antibody but may need to use it a bit higher concentration or probe longer.
    Date published: 2017-03-08
    Rated 5 out of 5 by from Excellent immunoperoxidase cytoplasmic stainingExcellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human liver tissue. -SCBT QC
    Date published: 2015-03-30
    Rated 5 out of 5 by from Nice Western Blot data of SULT1 expression in nonNice Western Blot data of SULT1 expression in non-transfected and human SULT1 transfected 293 whole cell lysates. -SCBT QC
    Date published: 2013-03-20
    • y_2025, m_9, d_6, h_5
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_4
    • loc_zh_CN, sid_376159, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 19ms
    • REVIEWS, PRODUCT
    SULT1 抗体 (B-4) is rated 5.0 out of 5 by 4.
    • y_2025, m_9, d_6, h_5
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_4
    • loc_zh_CN, sid_376159, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 113ms
    • REVIEWS, PRODUCT