Date published: 2025-9-6

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Stat2 抗体 (A-7): sc-1668

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说明书
  • Stat2抗体(A-7)是小鼠单克隆IgG1 κ, 在54篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Stat2 p113的C-terminus的氨基酸832-851之间
  • Stat2 抗体 (A-7) 推荐用于WB, IP, IF 和 ELISA,检测human 来源的 Stat2 p113
  • 抗Stat2抗体(A-7)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-1668 X, 200 µg/0.1 ml)
  • 关于如何获取Stat2 (A-7): sc-1668免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是Stat2 Antibody (A-7) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与Stat2 Antibody (A-7) 打包提供(请参阅下面的订购信息)。

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関連項目

Stat2抗体(A-7)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测人源Stat2蛋白。Stat2 (A-7) 抗体有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶、藻红蛋白、异硫氰酸荧光素和多种 Alexa Fluor® 结合物。Stat2 蛋白在干扰素和生长因子激活的信号传导通路中起着关键作用,特别是在与 Stat1 一起形成 ISGF3 转录因子复合物方面。ISGF3复合物对于介导转录反应以对抗病毒感染的免疫反应以及调节细胞生长和分化至关重要。Stat2与Stat1形成异二聚体,以增强信号级联的特异性和有效性,从而凸显其在免疫调节和细胞通讯中的重要性。Stat2 (A-7) 单克隆抗体有助于深入了解免疫信号传导机制和转录因子在细胞反应中的作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Stat2 抗体 (A-7) 参考文献:

  1. 呼吸道合胞病毒 NS1 蛋白通过 Elongin-Cullin E3 连接酶降解 STAT2。  |  Elliott, J., et al. 2007. J Virol. 81: 3428-36. PMID: 17251292
  2. Stat2-Drp1介导的线粒体质量增加是巨噬细胞促炎性分化的必要条件。  |  Yu, W., et al. 2020. Redox Biol. 37: 101761. PMID: 33080440
  3. 纤连蛋白-1/VEGFR2/STAT2信号轴通过调节卵巢癌类器官和细胞的糖酵解和血管生成来促进耐药性。  |  Wang, Z., et al. 2022. Cancer Commun (Lond). 42: 245-265. PMID: 35234370
  4. IL-20通过调节上皮细胞IFN/STAT2信号传导来控制实验性结肠炎的缓解。  |  Chiriac, MT., et al. 2024. Gut. 73: 282-297. PMID: 37884352
  5. 酪氨酸磷酸化的 Stat1 和 Stat2 加上一个 48 kDa 蛋白都与 DNA 接触,形成干扰素刺激基因因子 3。  |  Qureshi, SA., et al. 1995. Proc Natl Acad Sci U S A. 92: 3829-33. PMID: 7537377
  6. Jun 和 Stat3 的一种简称 Stat3 beta 的合作转录活性。  |  Schaefer, TS., et al. 1995. Proc Natl Acad Sci U S A. 92: 9097-101. PMID: 7568080
  7. 对多肽配体的转录反应:JAK-STAT 途径。  |  Schindler, C. and Darnell, JE. 1995. Annu Rev Biochem. 64: 621-51. PMID: 7574495
  8. 白细胞介素-3, 促红细胞生成素和催乳素可激活淋巴细胞中的 STAT5 类因子。  |  Pallard, C., et al. 1995. J Biol Chem. 270: 15942-5. PMID: 7608147
  9. Stat4,一种在早期骨髓分化过程中表达的新型γ干扰素激活位点结合蛋白。  |  Yamamoto, K., et al. 1994. Mol Cell Biol. 14: 4342-9. PMID: 8007943
  10. 白细胞介素-4 诱导的转录因子:IL-4 Stat.  |  Hou, J., et al. 1994. Science. 265: 1701-6. PMID: 8085155
  11. Stat3:一种 STAT 家族成员,在表皮生长因子和白细胞介素-6 的作用下通过酪氨酸磷酸化激活。  |  Zhong, Z., et al. 1994. Science. 264: 95-8. PMID: 8140422
  12. Jak-STAT 通路和转录激活对 IFNs 及其他细胞外信号蛋白的反应。  |  Darnell, JE., et al. 1994. Science. 264: 1415-21. PMID: 8197455

订购信息

产品名称产品编号规格价格数量收藏夹

Stat2 抗体 (A-7)

sc-1668
200 µg/ml
RMB2377.00

Stat2 (A-7): m-IgG Fc BP-HRP 套装

sc-528132
200 µg Ab; 10 µg BP
RMB2662.00

Stat2 (A-7): m-IgGκ BP-HRP 套装

sc-520436
200 µg Ab, 40 µg BP
RMB2662.00

Stat2 抗体 (A-7) X

sc-1668 X
200 µg/0.1 ml
RMB2377.00

Stat2 抗体 (A-7) AC

sc-1668 AC
500 µg/ml, 25% agarose
RMB3129.00

Stat2 抗体 (A-7) HRP

sc-1668 HRP
200 µg/ml
RMB2377.00

Stat2 抗体 (A-7) FITC

sc-1668 FITC
200 µg/ml
RMB2482.00

Stat2 抗体 (A-7) PE

sc-1668 PE
200 µg/ml
RMB2580.00

Stat2 抗体 (A-7) Alexa Fluor® 488

sc-1668 AF488
200 µg/ml
RMB2685.00

Stat2 抗体 (A-7) Alexa Fluor® 546

sc-1668 AF546
200 µg/ml
RMB2685.00

Stat2 抗体 (A-7) Alexa Fluor® 594

sc-1668 AF594
200 µg/ml
RMB2685.00

Stat2 抗体 (A-7) Alexa Fluor® 647

sc-1668 AF647
200 µg/ml
RMB2685.00

Stat2 抗体 (A-7) Alexa Fluor® 680

sc-1668 AF680
200 µg/ml
RMB2685.00

Stat2 抗体 (A-7) Alexa Fluor® 790

sc-1668 AF790
200 µg/ml
RMB2685.00

Stat2 (A-7) 中和勝肽

sc-1668 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-1668 P appropriate for?

Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Good antibodyThis antibody works well in western blot of human whole cell extracts.
Date published: 2021-05-31
Rated 4 out of 5 by from Funktioniert in Immunhistologie auf Hunde GewebeNachdem der "alte" Antikörper nach über 6 Jahren leer war, haben wir zuerst eine Trial-Size bestellt, der in der Immunhistochemie auf Paraffinhundegewebe gut funktionierte, in der Immunfluoreszenz jedoch nicht. Der gekaufte Antikörper jetzt liefert in der Immunhistochemie noch immer tadellose Ergebnisse und auch in der Immunfluoreszenz sind die Ergebnisse durch eine hohe Konzentration akzetabel.
Date published: 2017-11-22
Rated 5 out of 5 by from Good qualityGood antibody with single specific bands. 1:500 dilution in 5% milk
Date published: 2017-08-10
Rated 5 out of 5 by from Consistent and reliable!This antibody consistently shows a single band at the correct weight in Western Blot.
Date published: 2017-01-20
Rated 4 out of 5 by from Reasonably specific and sensitiveReasonably specific and sensitive, publishable results in WB with Huh7.5 cells. -SCBT Publication Review
Date published: 2015-03-04
Rated 5 out of 5 by from Antibody works well in human A549 cells for IFAntibody works well in human A549 cells for IF. -SCBT Publication Review
Date published: 2015-02-19
Rated 4 out of 5 by from IF: Satisfactory nuclear staining in Ramos cellsIF: Satisfactory nuclear staining in Ramos cells. -SCBT QC
Date published: 2015-01-21
Rated 5 out of 5 by from Clean blot with single strong band at expectedClean blot with single strong band at expected size in Ramos cells. -SCBT QC
Date published: 2014-07-16
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Stat2 抗体 (A-7) is rated 4.5 out of 5 by 8.
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