Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

SMP30 抗体 (E-11): sc-390098

4.8(6)
寫評論提問

说明书
  • SMP30 抗体 E-11 是小鼠单克隆 IgG1 κ,SMP30抗体, 在7篇文献中引用,规格为200 µg/ml
  • 免疫human物种的代表全长SMP30的氨基酸1-299
  • SMP30 抗体 (E-11) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 SMP30
  • 抗SMP30抗体(E-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取SMP30 (E-11): sc-390098免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 SMP30 抗体 (E-11) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与SMP30 抗体 (E-11) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

SMP30抗体(E-11)是一种IgG1 κ小鼠单克隆SMP30抗体(也称为SMP30抗体),可通过WB、IP、IF、IHC(P)和ELISA技术检测小鼠、大鼠和人类的SMP30蛋白。SMP30抗体(E-11)既可以是非偶联的抗SMP30抗体形式,也可以是多种偶联形式的抗SMP30抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。衰老标志蛋白-30(SMP30)在肝脏、肾脏和颌下腺中表达。在肾脏中,SMP30定位于肝细胞和肾近端小管上皮。SMP30的表达水平在发育过程中的组织成熟期间增加,并以不依赖雄激素的方式随年龄增长而减少。SMP30通过调节质膜钙泵的活性影响细胞内钙稳态。SMP30对钙水平的影响似乎可以保护细胞免受凋亡。小鼠SMP30基因的启动子序列包含未知和已知转录因子的结合位点,包括Sp1、AP2、CCAAT框、Lyf-1和GATA-1。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SMP30 抗体 (E-11) 参考文献:

  1. 小鼠缺乏 SMP30 会导致中性脂质和磷脂在肝脏中积累,并缩短寿命。  |  Ishigami, A., et al. 2004. Biochem Biophys Res Commun. 315: 575-80. PMID: 14975739
  2. 大鼠肝脏中衰老标志蛋白-30(SMP30)的纯化及其与雄激素无关的随年龄增长而减少的现象。  |  Fujita, T., et al. 1992. Biochim Biophys Acta. 1116: 122-8. PMID: 1581340
  3. 氧化还原敏感 DNA 结合位点导致 SMP30 受 ERK 通路的年龄相关性下调,并受卡路里限制逆转。  |  Jung, KJ., et al. 2006. Antioxid Redox Signal. 8: 671-80. PMID: 16677110
  4. SMP30 基因敲除小鼠的肾小管细胞衰老加速。  |  Yumura, W., et al. 2006. Histol Histopathol. 21: 1151-6. PMID: 16874657
  5. 建立并鉴定缺乏维生素 C 的 Immortomouse/SMP30/GNL 基因敲除杂交小鼠的肝细胞,以研究维生素 C 的转运。  |  Amano, A., et al. 2011. J Biochem. 150: 671-8. PMID: 21903636
  6. 维生素 C 缺乏对 SMP30/GNL 基因敲除小鼠紫外线辐射-B 诱导的白内障的影响  |  Ishikawa, Y., et al. 2012. Exp Eye Res. 94: 85-9. PMID: 22155581
  7. 抗坏血酸缺乏会导致 SMP30/GNL 基因敲除无毛小鼠表皮萎缩和紫外线诱导的皮肤色素沉着。  |  Sato, Y., et al. 2012. J Invest Dermatol. 132: 2112-5. PMID: 22495180
  8. 衰老标志蛋白-30(SMP30)的缺乏会损害心肌诱导的冠状动脉小动脉扩张,这与活性氧有关。  |  Mizukami, H., et al. 2013. Int J Mol Sci. 14: 9408-23. PMID: 23629672
  9. 小鼠和人类 SMP30 的金属依赖性结构和功能特性比较分析。  |  Dutta, RK., et al. 2019. PLoS One. 14: e0218629. PMID: 31220150
  10. 衰老标志蛋白-30(SMP30)的基因调控:随组织成熟而协调上调,随衰老而逐渐下调。  |  Fujita, T., et al. 1996. Mech Ageing Dev. 87: 219-29. PMID: 8794449

订购信息

产品名称产品编号规格价格数量收藏夹

SMP30 抗体 (E-11)

sc-390098
200 µg/ml
RMB2377.00

SMP30 (E-11): m-IgG Fc BP-HRP 套装

sc-530059
200 µg Ab; 10 µg BP
RMB2662.00

SMP30 (E-11): m-IgGκ BP-HRP 套装

sc-523401
200 µg Ab, 40 µg BP
RMB2662.00

SMP30 (E-11): m-IgG1 BP-HRP 套装

sc-543847
200 µg Ab; 20 µg BP
RMB2662.00

SMP30 抗体 (E-11) AC

sc-390098 AC
500 µg/ml, 25% agarose
RMB3129.00

SMP30 抗体 (E-11) HRP

sc-390098 HRP
200 µg/ml
RMB2377.00

SMP30 抗体 (E-11) FITC

sc-390098 FITC
200 µg/ml
RMB2482.00

SMP30 抗体 (E-11) PE

sc-390098 PE
200 µg/ml
RMB2580.00

SMP30 抗体 (E-11) Alexa Fluor® 488

sc-390098 AF488
200 µg/ml
RMB2685.00

SMP30 抗体 (E-11) Alexa Fluor® 546

sc-390098 AF546
200 µg/ml
RMB2685.00

SMP30 抗体 (E-11) Alexa Fluor® 594

sc-390098 AF594
200 µg/ml
RMB2685.00

SMP30 抗体 (E-11) Alexa Fluor® 647

sc-390098 AF647
200 µg/ml
RMB2685.00

SMP30 抗体 (E-11) Alexa Fluor® 680

sc-390098 AF680
200 µg/ml
RMB2685.00

SMP30 抗体 (E-11) Alexa Fluor® 790

sc-390098 AF790
200 µg/ml
RMB2685.00

I am using SMP30 (E-11): sc-390098 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: AbPolly
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_390098, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 110ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from works well for WBWorks well on neonatal mouse lungs at concentration of 30ug. Antibody dilution will be 1:500 for overnight at 4oC
Date published: 2024-12-13
Rated 5 out of 5 by from Excellent worksThe comparison with G-10 antibody, E-11 works more specific for the detection of mouse antigen.
Date published: 2021-07-01
Rated 5 out of 5 by from great antibodyThis antobody is good for western blot, it can be used at a dilution of 1:1000, the good bands can be tested easily in cardiomyocytes.
Date published: 2017-09-15
Rated 4 out of 5 by from greatI use this antibody with the dilution 1:500 and got a clear band
Date published: 2017-08-02
Rated 5 out of 5 by from Produced exceptional immunoperoxidase cytoplasmicProduced exceptional immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human liver tissue. -SCBT QC
Date published: 2015-04-02
Rated 5 out of 5 by from Produced positive Western Blot data of SMP30Produced positive Western Blot data of SMP30 expression in Hep G2 whole cell lysate and human brain and mouse brain tissue extracts. -SCBT QC
Date published: 2014-01-17
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_390098, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
SMP30 抗体 (E-11) is rated 4.8 out of 5 by 6.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_6
  • loc_zh_CN, sid_390098, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 103ms
  • REVIEWS, PRODUCT