Date published: 2025-9-8

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RGS16 抗体 (A-9): sc-166083

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说明书
  • RGS16 抗体 A-9 是小鼠单克隆 IgG2b κ,RGS16抗体, 在1篇文献中引用,规格为200 µg/ml
  • 针对氨基酸103-202的抗原,在RGS16的C-terminus处映射,human来源
  • RGS16 抗体 (A-9) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 RGS16
  • 抗RGS16抗体(A-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取RGS16 (A-9): sc-166083免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是RGS16 Antibody (A-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与RGS16 Antibody (A-9) 打包提供(请参阅下面的订购信息)。

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関連項目

RGS16抗体(A-9)是一种IgG2b κ小鼠单克隆RGS16抗体(也称为RGSR抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类的RGS16蛋白。RGS16抗体(A-9)既可以以非偶联的抗RGS16抗体形式提供,也可以以多种偶联形式的抗RGS16抗体提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。G蛋白信号调节因子(RGS蛋白)是一类高度多样化、多功能的信号蛋白,具有一个保守的120个氨基酸结构域(RGS结构域)。RGS结构域直接与活化的Ga亚基结合,并作为GTP酶激活蛋白(GAPs)来减弱和/或调节由Ga-GTP和Gbg介导的激素和神经递质受体启动的信号传导。RGS蛋白缩短了活化G蛋白的寿命。RGS16在视网膜中高表达。RGS16的过表达抑制了G蛋白偶联的促有丝分裂信号转导和丝裂原活化蛋白激酶(MAPK)信号级联的激活。RGS16增强了转导素的GTP水解速率,这表明RGS16可能在调节光转导级联反应中的信号动力学中发挥作用。编码RGS16的基因定位于人类染色体1q25-q31。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RGS16 抗体 (A-9) 参考文献:

  1. RGS 蛋白在细胞信号中的新作用。  |  Hepler, JR. 1999. Trends Pharmacol Sci. 20: 376-82. PMID: 10462761
  2. RGS16可减轻肺部Th2/Th17炎症反应。  |  Shankar, SP., et al. 2012. J Immunol. 188: 6347-56. PMID: 22593615
  3. RGS16 可促进胶质瘤的发展并成为预后因素。  |  Huang, R., et al. 2020. CNS Neurosci Ther. 26: 791-803. PMID: 32319728
  4. Rgs16促进抗肿瘤CD8+ T细胞衰竭。  |  Weisshaar, N., et al. 2022. Sci Immunol. 7: eabh1873. PMID: 35622904
  5. RGS16在溃疡性结肠炎粘膜炎症中起关键作用。  |  Zhu, F., et al. 2022. Eur J Gastroenterol Hepatol. 34: 993-999. PMID: 35830366
  6. RGS16受let-7c-5p调节,通过激活PI3K-AKT途径促进胶质瘤进展。  |  Wang, C., et al. 2023. Front Med. 17: 143-155. PMID: 36414916
  7. 精神分裂症患者基因表达荟萃分析显示,布罗德曼10区RGS2和RGS16的表达上调。  |  Shriebman, Y., et al. 2023. Eur J Neurosci. 57: 360-372. PMID: 36443250
  8. RGS16调节Hippo-YAP活性,促进食管癌细胞增殖和迁移。  |  Zhang, Y., et al. 2023. Biochem Biophys Res Commun. 675: 122-129. PMID: 37473526
  9. RGS16在Tyr168处的磷酸化通过ERK途径促进HBeAg介导的巨噬细胞活化,加速肝脏损伤。  |  Tian, M., et al. 2024. J Mol Med (Berl). 102: 257-272. PMID: 38141114
  10. RGS-r是一种视网膜特异性RGS蛋白,能与转导蛋白的中间构象结合,并增强循环。  |  Chen, CK., et al. 1996. Proc Natl Acad Sci U S A. 93: 12885-9. PMID: 8917514
  11. 克隆视网膜上丰富的 G 蛋白信号调节因子(RGS-r/RGS16):人类基因的基因组结构和染色体定域。  |  Snow, BE., et al. 1998. Gene. 206: 247-53. PMID: 9469939
  12. 心肌细胞表达十种 RGS 蛋白的 mRNA:心室肌细胞和培养心房中 RGS mRNA 表达的变化。  |  Kardestuncer, T., et al. 1998. FEBS Lett. 438: 285-8. PMID: 9827562

订购信息

产品名称产品编号规格价格数量收藏夹

RGS16 抗体 (A-9)

sc-166083
200 µg/ml
RMB2377.00

RGS16 (A-9): m-IgGκ BP-HRP 套装

sc-521504
200 µg Ab, 40 µg BP
RMB2662.00

RGS16 (A-9): m-IgG2b BP-HRP 套装

sc-548916
200 µg Ab; 10 µg BP
RMB2662.00

RGS16 抗体 (A-9) AC

sc-166083 AC
500 µg/ml, 25% agarose
RMB3129.00

RGS16 抗体 (A-9) HRP

sc-166083 HRP
200 µg/ml
RMB2377.00

RGS16 抗体 (A-9) FITC

sc-166083 FITC
200 µg/ml
RMB2482.00

RGS16 抗体 (A-9) PE

sc-166083 PE
200 µg/ml
RMB2580.00

RGS16 抗体 (A-9) Alexa Fluor® 488

sc-166083 AF488
200 µg/ml
RMB2685.00

RGS16 抗体 (A-9) Alexa Fluor® 546

sc-166083 AF546
200 µg/ml
RMB2685.00

RGS16 抗体 (A-9) Alexa Fluor® 594

sc-166083 AF594
200 µg/ml
RMB2685.00

RGS16 抗体 (A-9) Alexa Fluor® 647

sc-166083 AF647
200 µg/ml
RMB2685.00

RGS16 抗体 (A-9) Alexa Fluor® 680

sc-166083 AF680
200 µg/ml
RMB2685.00

RGS16 抗体 (A-9) Alexa Fluor® 790

sc-166083 AF790
200 µg/ml
RMB2685.00

Is there a recommended concentration for use in FCM?

Asked by: Carly2
Thank you for your question. We recommend 1ug per 1 million cells. https://www.scbt.com/resources/protocols/flow-cytometry
Answered by: BlakeJ
Date published: 2023-03-24

I recently purchased the RGS16-PE Antibody (A-9): sc-166083 to stain the RGS16 protein in my cells. However, I realized it is not specified if this antibody is compatible with flow staining.

Asked by: Prathiksha Nagarajan
Thank you for your question. We warranty this antibody for WB, IP, IF , ELISA,IHC and FCM.
Answered by: BlakeJ
Date published: 2023-02-23

Are there any issues with using sc-166083: RGS16 (A-9) mouse monoclonal primary antibody on mouse samples?

Asked by: Cweed
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-166083 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
  • y_2025, m_9, d_6, h_5CST
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Rated 5 out of 5 by from Satisfactory Western blot data of RGS16 expressionSatisfactory Western blot data of RGS16 expression in non-transfected and mouse RGS16 transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-09-18
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RGS16 抗体 (A-9) is rated 5.0 out of 5 by 1.
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