Date published: 2025-9-9
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
Renin Antibody (A-1) - Western Blotting - Image 356178
肾素抗体 (A-1): sc-137252. Hep G2 (A), ES-2 (B), c4 (C), AMJ2-C8 (D) 和 PC-12 (E) 全细胞裂解液中 Renin 表达的 Western 印迹分析.
肾素抗体 (A-1): sc-137252. Hep G2 (A), ES-2 (B), c4 (C), AMJ2-C8 (D) 和 PC-12 (E) 全细胞裂解液中 Renin 表达的 Western 印迹分析.

Renin 抗体 (A-1): sc-137252

4.6(5)
寫評論提問

说明书
  • Renin抗体(A-1)是小鼠单克隆IgG1 κ, 在20篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于mouse物种的Renin的内部区域内的氨基酸163-197之间
  • 抗-Renin 抗体 (A-1) 推荐用于 WB, IP, IF 和 ELISA，检测mouse, rat 和human 来源的 precursor and mature heavy chain Renin
  • 抗Renin抗体（A-1）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Renin (A-1): sc-137252的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG1 BP-HRP是Renin Antibody (A-1) for WB applications. 的首选辅助检测试剂，这些试剂现与Renin Antibody (A-1) 打包提供（请参阅下面的订购信息）。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

肾素抗体（A-1）是一种IgG1 κ小鼠单克隆肾素抗体（也称为肾素抗体或REN抗体），可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的前体和成熟重链肾素。肾素抗体（A-1）既有非偶联形式的抗肾素抗体，也有多种偶联形式的抗肾素抗体，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。肾素是一种高度特异性的内肽酶，可介导循环底物血管紧张素原的裂解，产生血管紧张素I。然后，血管紧张素转化酶I（ACE）完成从血管紧张素I到血管紧张素II的转化，这在调节电解质平衡和血压方面具有重要意义。交感神经刺激（β1-肾上腺素能受体）、肾动脉低血压和肾远端小管钠传递的减少都会发出肾素释放的信号。肾素-血管紧张素系统（RAS）对于调节血容量、动脉压以及正常的心脏和血管功能至关重要。肾素由肾脏肾小球旁器（JGA）中的修饰平滑肌细胞合成并分泌。尽管其在其他组织（包括大脑）中的表达已得到验证，但其可能发挥的稳态作用尚有待确定。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Renin 抗体 (A-1) 参考文献:

  1. 醛固酮和肾素测量。  |  Cartledge, S. and Lawson, N. 2000. Ann Clin Biochem. 37 (Pt 3): 262-78. PMID: 10817239
  2. 低肾素高血压状态下的血浆肾素和醛固酮测量。  |  Sealey, JE., et al. 2005. Trends Endocrinol Metab. 16: 86-91. PMID: 15808804
  3. 高血压中的肾素抑制。  |  Gradman, AH. and Kad, R. 2008. J Am Coll Cardiol. 51: 519-28. PMID: 18237679
  4. 使用阿利吉仑抑制肾素。  |  Wuerzner, G. and Azizi, M. 2008. Clin Exp Pharmacol Physiol. 35: 426-30. PMID: 18307734
  5. 肾素抑制剂，临床经验。  |  Westermann, D., et al. 2008. J Mol Med (Berl). 86: 691-5. PMID: 18437334
  6. 肾素抑制剂。  |  Kleinert, HD., et al. 1991. Adv Pharmacol. 22: 207-50. PMID: 1958502
  7. 作为高血压生物标志物的肾素和肾素原。  |  Jan Danser, AH. 2012. Curr Opin Nephrol Hypertens. 21: 508-14. PMID: 22820372
  8. 压力之下肾脏肾素细胞中控制肾素的气压感受器机制。  |  Nakagawa, P. and Sigmund, CD. 2021. Circ Res. 129: 277-279. PMID: 34236885
  9. 控制肾素释放。  |  Vander, AJ. 1967. Physiol Rev. 47: 359-82. PMID: 4864539
  10. 肾素受抑制的儿童高血压。  |  New, MI. and Levine, LS. 1980. Endocr Rev. 1: 421-30. PMID: 6265200

订购信息

产品名称产品编号规格价格数量收藏夹

Renin 抗体 (A-1)

sc-137252
200 µg/ml
RMB2377.00

Renin (A-1): m-IgG Fc BP-HRP 套装

sc-527131
200 µg Ab; 10 µg BP
RMB2662.00

Renin (A-1): m-IgG1 BP-HRP 套装

sc-532504
200 µg Ab; 20 µg BP
RMB2662.00

Renin 抗体 (A-1) AC

sc-137252 AC
500 µg/ml, 25% agarose
RMB3129.00

Renin 抗体 (A-1) HRP

sc-137252 HRP
200 µg/ml
RMB2377.00

Renin 抗体 (A-1) FITC

sc-137252 FITC
200 µg/ml
RMB2482.00

Renin 抗体 (A-1) PE

sc-137252 PE
200 µg/ml
RMB2580.00

Renin 抗体 (A-1) Alexa Fluor® 488

sc-137252 AF488
200 µg/ml
RMB2685.00

Renin 抗体 (A-1) Alexa Fluor® 546

sc-137252 AF546
200 µg/ml
RMB2685.00

Renin 抗体 (A-1) Alexa Fluor® 594

sc-137252 AF594
200 µg/ml
RMB2685.00

Renin 抗体 (A-1) Alexa Fluor® 647

sc-137252 AF647
200 µg/ml
RMB2685.00

Renin 抗体 (A-1) Alexa Fluor® 680

sc-137252 AF680
200 µg/ml
RMB2685.00

Renin 抗体 (A-1) Alexa Fluor® 790

sc-137252 AF790
200 µg/ml
RMB2685.00

Renin (A-1) 中和勝肽

sc-137252 P
100 µg/0.5 ml
RMB511.00

what is the cross reactivity with rat prorenin and sensitivity

Asked by: AMP1
Thank you for your question. Anti-Renin Antibody (A-1): sc-137252 recognises its target based on the amino acid sequence 163-197, which is present in unprocessed Renin protein. As such, the antibody would detect both mature protein and prorenin, but not the activation peptide sequence.
Answered by: Tech Support Europe
Date published: 2021-12-29

What application is the blocking peptide sc-137252 P appropriate for?

Asked by: Dr Ninau Qelp
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2023-11-29
  • y_2025, m_8, d_30, h_9CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_137252, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 102ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Good antibodyThe Renin Antibody (A-1): sc-137252 works well for Western blot applications, showing clear bands with minimal background. This antibody has also been cited several times for further verification.
Date published: 2017-01-24
Rated 5 out of 5 by from This has worked well in WBThis has worked well in WB.
Date published: 2015-10-20
Rated 4 out of 5 by from Great band seen in WB using KNRK whole cell lysateGreat band seen in WB using KNRK whole cell lysate. -SCBT QC
Date published: 2015-04-11
Rated 4 out of 5 by from Nice bands seen in WB using KNice bands seen in WB using K-562 and HeLa whole cell lysates. -SCBT QC
Date published: 2015-01-23
Rated 5 out of 5 by from WB publishable data with mouse right kidneyWB publishable data with mouse right kidney - SCBT Publication Review
Date published: 2013-07-20
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_137252, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 16ms
  • REVIEWS, PRODUCT
Renin 抗体 (A-1) is rated 4.6 out of 5 by 5.
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_137252, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 106ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。