Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

RANK 抗体 (H-7): sc-374360

4.5(10)
寫評論提問

说明书
  • RANK 抗体 H-7 是小鼠单克隆 IgG1 κ,RANK抗体, 在31篇文献中引用,规格为200 µg/ml
  • 免疫human物种的RANK的氨基酸317-616
  • RANK 抗体 (H-7) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 RANK
  • 抗RANK抗体(H-7)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取RANK (H-7): sc-374360免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是RANK Antibody (H-7) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与RANK Antibody (H-7) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

RANK抗体(H-7)是一种IgG1 κ小鼠单克隆RANK抗体(也称为TNFRSF11A抗体、ODFR抗体或CD265抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类的RANK蛋白。RANK抗体(H-7)既可以是非偶联的抗RANK抗体形式,也可以是多种偶联形式的抗RANK抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。肿瘤坏死因子(TNF)受体超家族的成员与TNF受体相关因子(TRAF)家族的信号分子相互作用,以激活NFκB和JNK通路。RANK(NFκB的受体激活剂)是在树突状细胞上鉴定的TNFR家族成员。这种I型膜受体在多种组织中表达。RANK的C末端对于RANK结合TRAF2、5和6是必需的,并且对于刺激NFκB的激活也是必需的。该受体的配体RANKL(也称为TRANCE或ODF)是主要在淋巴组织和T细胞系中表达的II型跨膜蛋白。RANKL似乎是T细胞和破骨细胞的重要调节因子。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RANK 抗体 (H-7) 参考文献:

  1. RANK-Fc:骨髓瘤中RANK-L的治疗拮抗剂。  |  Sordillo, EM. and Pearse, RN. 2003. Cancer. 97: 802-12. PMID: 12548579
  2. RANK、RANKL和骨保护素在关节炎性骨丢失中的作用。  |  Bezerra, MC., et al. 2005. Braz J Med Biol Res. 38: 161-70. PMID: 15785827
  3. MiR-503通过靶向RANK来调节破骨细胞的形成。  |  Chen, C., et al. 2014. J Bone Miner Res. 29: 338-47. PMID: 23821519
  4. 腮腺癌中的RANK和RANK配体表达。  |  Franchi, A., et al. 2018. Appl Immunohistochem Mol Morphol. 26: 478-482. PMID: 29494398
  5. RANKL/RANK通路及其抑制剂RANK-Fc在子宫平滑肌瘤生长中的作用。  |  Ikhena, DE., et al. 2018. J Clin Endocrinol Metab. 103: 1842-1849. PMID: 29741640
  6. RANK在妊娠期间驱动结构化肠上皮扩张。  |  Onji, M., et al. 2025. Nature. 637: 156-166. PMID: 39633049
  7. TRANCE 是肿瘤坏死因子受体家族的一种新型配体,可激活 T 细胞中的 c-Jun N 端激酶。  |  Wong, BR., et al. 1997. J Biol Chem. 272: 25190-4. PMID: 9312132
  8. TNF 受体相关因子 2 下游的肿瘤坏死因子(TNF)受体 1 信号传导。核因子卡巴波(NFkappaB)诱导激酶需要激活活化蛋白 1 和 NFkappaB,但不需要激活 c-Jun N 端激酶/应激活化蛋白激酶。  |  Natoli, G., et al. 1997. J Biol Chem. 272: 26079-82. PMID: 9334169
  9. TNF 受体的同源物及其配体能增强 T 细胞的生长和树突状细胞的功能。  |  Anderson, DM., et al. 1997. Nature. 390: 175-9. PMID: 9367155
  10. 肿瘤坏死因子(TNF)受体 1 通过 TNF 受体相关因子 2 和生殖中心激酶相关依赖途径激活应激活化蛋白激酶/c-Jun N 端激酶,而非 NF-kappaB。  |  Shi, CS. and Kehrl, JH. 1997. J Biol Chem. 272: 32102-7. PMID: 9405407
  11. NF-kappaB受体激活剂(RANK)胞内结构域的特征。与肿瘤坏死因子受体相关因子的相互作用以及 NF-kappab 和 c-Jun N 端激酶的激活。  |  Darnay, BG., et al. 1998. J Biol Chem. 273: 20551-5. PMID: 9685412
  12. 信号转导因子 TRAF 家族通过 TRANCE 受体介导 NF-kappaB 激活。  |  Wong, BR., et al. 1998. J Biol Chem. 273: 28355-9. PMID: 9774460

订购信息

产品名称产品编号规格价格数量收藏夹

RANK 抗体 (H-7)

sc-374360
200 µg/ml
$316.00

RANK (H-7): m-IgG Fc BP-HRP 套装

sc-529728
200 µg Ab; 10 µg BP
$354.00

RANK (H-7): m-IgGκ BP-HRP 套装

sc-522711
200 µg Ab, 40 µg BP
$354.00

RANK (H-7): m-IgG1 BP-HRP 套装

sc-543656
200 µg Ab; 20 µg BP
$354.00

RANK 抗体 (H-7) AC

sc-374360 AC
500 µg/ml, 25% agarose
$416.00

RANK 抗体 (H-7) HRP

sc-374360 HRP
200 µg/ml
$316.00

RANK 抗体 (H-7) FITC

sc-374360 FITC
200 µg/ml
$330.00

RANK 抗体 (H-7) PE

sc-374360 PE
200 µg/ml
$343.00

RANK 抗体 (H-7) Alexa Fluor® 488

sc-374360 AF488
200 µg/ml
$357.00

RANK 抗体 (H-7) Alexa Fluor® 546

sc-374360 AF546
200 µg/ml
$357.00

RANK 抗体 (H-7) Alexa Fluor® 594

sc-374360 AF594
200 µg/ml
$357.00

RANK 抗体 (H-7) Alexa Fluor® 647

sc-374360 AF647
200 µg/ml
$357.00

RANK 抗体 (H-7) Alexa Fluor® 680

sc-374360 AF680
200 µg/ml
$357.00

RANK 抗体 (H-7) Alexa Fluor® 790

sc-374360 AF790
200 µg/ml
$357.00

Can this antibody be used in Western Blotting of rabbit bone tissue?Thank you!

Asked by: jack35
Thank you for your question. This antibody does not have data or any product citations in rabbit samples at this time. Please contact our Technical Service Department if you would like our assistance in checking the antibody's antigen sequence for similarity with the RANK protein in rabbits.
Answered by: Technical Support
Date published: 2020-04-20

I plan to do the immonstaining of Rank+ cells in the bone. Can I apply for a sample of this antibody to do the experiment? Thank you.

Asked by: Weiping Su
Please contact our Technical Service Department for more information on how to receive a free 10 ug sample of this monoclonal antibody.
Answered by: Technical Support
Date published: 2019-01-14

RANK抗体(H-7): sc-374360 を購入したいと考えています。日本円でのお値段を教えてください。

Asked by: Kazuhiro
Thank you for your question. If you would like to check the price in Japanese Yen(JPY), please contact one of our local distributors in Japan. https://www.scbt.com/scbt/resources/distributors Please feel free to contact me if I may be of further assistance. お問い合わせを頂きまして、誠にありがとうございました。日本での購入は弊社の日本での代理店へお勧めします。納期と日本円での価格は代理店へご連絡ください。 代理店は下記とな ります。 https://www.scbt.com/scbt/resources/distributors その他の不明点等がございましたら、またご連絡ください。
Answered by: Technical Support 8
Date published: 2018-12-21

Hi, Can i get this free sample antibody of RANK (H-7, sc-374360). i would like to test this antibody for our experiment. let me know. Thank you.

Asked by: Sehwan
Thank you for your question. Please contact Technical Service for more information on how to receive a 10 μg sample of our well characterized monoclonal antibody.
Answered by: Technical Support
Date published: 2018-12-05

Can RANK (H-7): sc-374360 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: AbPolly
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, RANK (H-7): sc-374360 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_5
  • loc_zh_CN, sid_374360, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 90ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Buoni risultati su osteoclastiTestati su tessuto formalin-fixed and paraffin-embedded. A volte la reattività non è fortissima.
Date published: 2024-01-11
Rated 4 out of 5 by from Western blotting testing for Mouse macrophage cellI detected the expression of RANK of mouse macrophage cells, and compare B-8 and H-7. The H-7 is good for deteting mouse macrophage cells by western blotting
Date published: 2019-03-15
Rated 4 out of 5 by from It can be usedI applied for the sample of this product, and I got bands which were a little bit shallow.
Date published: 2018-05-06
Rated 4 out of 5 by from 实验结果理想一个月前在贵公司申请免费抗体小样,该抗体效果还可以,值得购买,稀释比例大概是1:250,推荐过夜孵育,曝光时间长一点
Date published: 2017-10-16
Rated 5 out of 5 by from 1:600 dilutionRANK is a good marker in bone metabolism testing. We detected the expression of RANKL in osteoclasts cell by RANKL antibody,recommend 1:600 dilution, the secondary from CWBIO, 1:3000 dilution, the target protein expression is very high.
Date published: 2017-09-16
Rated 5 out of 5 by from Great work wellI bought RANK (H-7) a few month ago and I could improve my western bot than other RANK antibody
Date published: 2017-06-28
Rated 4 out of 5 by from Clear bandsWe got RANK antibody 3 months ago . It was applied to WB , the bands were clear , but the background was a bit high .
Date published: 2017-06-13
Rated 5 out of 5 by from Great for RANKUsed for western blotting with mouse RANK transfected, the antibody is good to WB at dilution 1:1000.
Date published: 2017-02-12
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_10
  • loc_zh_CN, sid_374360, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
RANK 抗体 (H-7) is rated 4.5 out of 5 by 10.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_10
  • loc_zh_CN, sid_374360, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 101ms
  • REVIEWS, PRODUCT