Date published: 2025-9-6

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RAGE 抗体 (D-5): sc-74535

4.3(4)
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说明书
  • RAGE抗体(D-5)是小鼠单克隆IgG3 κ, 在5篇文献中引用,规格为200 µg/ml
  • 免疫human物种的RAGE的氨基酸1-300
  • 推荐用于 mouse, rat 和 human 来源的RAGE WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 RAGE (A-9): sc-365154,可查看有标记的 RAGE 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成RAGE 抗体 (D-5)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

蛋白质的高级糖基化终末产物(AGEs)是与多种疾病相关的非酶糖基化蛋白质,包括糖尿病和其他血管疾病,以及淀粉样变性。这些蛋白质通过特定的细胞表面受体分子调节细胞功能,如RAGE(晚期糖基化终末产物受体)。RAGE是一种1型膜蛋白,存在于内皮细胞、单核吞噬细胞和血管平滑肌细胞的表面。AGEs与RAGE结合导致细胞氧化应激的诱导和转录因子NFkB的激活。有证据表明,氧化应激的诱导导致涉及p21ras和MAP激酶的细胞内级联反应的激活,从而导致转录的激活。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

RAGE 抗体 (D-5)

sc-74535
200 µg/ml
RMB2377.00

Can RAGE (D-5): sc-74535 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Cweed
Thank you for your question. Yes, RAGE (D-5): sc-74535 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-25
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Rated 4 out of 5 by from Various publishable data in WB using humanVarious publishable data in WB using human HEK293 cells. -SCBT Publication Review
Date published: 2015-04-25
Rated 4 out of 5 by from Great band seen in WB using human recombinantGreat band seen in WB using human recombinant RAGE protein. -SCBT QC
Date published: 2015-04-16
Rated 5 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-01-29
Rated 4 out of 5 by from Publishable data in WB using rat liver and aortaPublishable data in WB using rat liver and aorta. -SCBT Publication Review
Date published: 2013-04-13
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RAGE 抗体 (D-5) is rated 4.3 out of 5 by 4.
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