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Rab 5C 抗体 (D-6): sc-374041

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说明书
  • Rab 5C抗体(D-6)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Rab 5C的C-terminus的氨基酸186-216之间
  • 推荐用于 mouse, rat 和 human 来源的Rab 5C WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine, bovine and porcine
  • 看 Rab 5 (D-11): sc-46692,可查看有标记的 Rab 5C 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是Rab 5C Antibody (D-6) for WB applications. 的首选辅助检测试剂,这些试剂现与Rab 5C Antibody (D-6) 打包提供(请参阅下面的订购信息)。

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包括R-Ras、Rap、Ral/Rec和Rho/Rab亚家族在内的Ras相关鸟嘌呤核苷酸结合蛋白超家族与Ras p21具有30-60%的同源性。累积的数据表明Rab蛋白在内吞作用或生物合成蛋白转运中起着重要作用。新合成的蛋白质从内质网运输到高尔基复合体的各个部位以及分泌囊泡的每一个阶段都涉及到载体囊泡的运动,这一过程似乎与Rab蛋白的功能有关。在酵母中,与Rab蛋白有40%同源性的SEC4蛋白与分泌囊泡相关,这一观察结果支持了Rab蛋白也可能直接指导分泌囊泡向质膜的胞吐作用的可能性。目前已经确定了至少八种Rab亚家族成员,每种成员都出现在膜转运途径的特定阶段。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Rab 5C 抗体 (D-6)

sc-374041
200 µg/ml
RMB2377.00

Rab 5C (D-6): m-IgG Fc BP-HRP 套装

sc-540416
200 µg Ab; 10 µg BP
RMB2662.00

Rab 5C (D-6): m-IgG1 BP-HRP 套装

sc-542106
200 µg Ab; 20 µg BP
RMB2662.00

Rab 5C (D-6) 中和勝肽

sc-374041 P
100 µg/0.5 ml
RMB511.00

Hi, I am looking for the anti-Rab5c antibody. Protein of my interest i.e XP_014048348.1 has 90% identity to given protein for the human Rab5c. I was wonderning if I can use this antibody for protein of my interest. What would you suggest?

Asked by: Anep
Thank you for your question. There is not significant sequence identity shared between this antibody’s antigen and the predicted protein sequence you provided so we would not expect cross-reactivity. One possible alternative antibody, Rab 5 Antibody (D-11): sc-46692, is raised against amino acids 1-215 full length Rab 5A. There is 83% sequence identity shared with the predicted protein sequence you provided. This is significant, and the antibody may be able to detect the protein in your Salmon samples. However, since this is a monoclonal antibody, the alignment would need to be 100% for us to be guarantee reactivity.
Answered by: Technical Support
Date published: 2019-04-13

What application is the blocking peptide sc-374041 P appropriate for?

Asked by: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Great monoclonal antibodyGreat monoclonal antibody, good specificity and strong signal strength for WB in mouse Rab 5C transfected 293T lysate. -SCBT QC
Date published: 2013-03-15
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Rab 5C抗体 (D-6) is rated 4.5 out of 5 by 2.
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