Date published: 2025-9-7

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PRX V 抗体 (B-7): sc-133073

5.0(7)
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说明书
  • PRX V抗体(B-7)是小鼠单克隆IgG2b κ, 在3篇文献中引用,规格为200 µg/ml
  • 免疫human物种的代表全长PRX V的氨基酸1-214
  • 推荐用于 human 来源的PRX V WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG2b BP-HRP 是PRX V 抗体 (B-7) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与PRX V 抗体 (B-7) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

过氧化物还原酶(PRX)家族包含六种抗氧化蛋白,即PRX I、II、III、IV、V和VI,它们通过防止酶的金属催化氧化来保护细胞免受活性氧(ROS)的侵害。PRX蛋白主要利用硫氧还蛋白作为电子供体进行抗氧化,尽管它们对于氢过氧化物底物相当混杂。除了保护细胞免受ROS侵害外,过氧化物还原酶还参与细胞增殖、分化和基因表达。PRX I、II、IV和VI显示出弥漫性细胞质定位,而PRX III和V则显示出独特的线粒体定位。人类PRX I基因编码一种在多种组织中表达的蛋白质,包括肝、肾、睾丸、肺和神经系统。PRX II在睾丸中表达,而PRX III在肺中表达。PRX I、II和III在乳腺癌中过度表达,可能参与其发展或进展。在阿尔茨海默病(AD)和唐氏综合征(DS)中PRX I和II的蛋白水平上调表明PRX I和II参与了它们的发病机制。人类PRX IV基因在许多组织中大量表达。PRX IV以前体蛋白的形式存在,仅在睾丸中检测到,是加工后的分泌物形式。PRX V也存在两种形式,即长和短。与PRX IV一样,PRX V的长形式在睾丸中高度表达。PRX V的短形式表达更广泛,在肝、肾、心和肺中高表达。PRX VI是一种1-Cys过氧化物还原酶(也称为抗氧化蛋白2或AOP2),在大多数组织中高度表达,特别是在上皮细胞中。PRX VI定位于细胞质中,独立于其他过氧化物还原酶和抗氧化蛋白发挥作用,专门负责抗氧化防御、肺磷脂代谢以及保护角质形成细胞免受活性氧诱导的细胞死亡。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

PRX V 抗体 (B-7)

sc-133073
200 µg/ml
RMB2377.00

PRX V (B-7): m-IgG2b BP-HRP 套装

sc-548484
200 µg Ab; 10 µg BP
RMB2662.00

I am using PRX V (B-7): sc-133073 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: DefinitelyNotMatt
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from satisfied bandsPRX V antibody works well for WB at the concentration of 1:800, with satisfied bands.
Date published: 2017-05-28
Rated 5 out of 5 by from clear band.Western blotting detection of good human cells, WB diluted 1:1000 clear band.
Date published: 2017-05-28
Rated 5 out of 5 by from worked really wellThis antibody worked really well for us in both WB and IF. Very pleased result, strong signal for both.
Date published: 2017-02-26
Rated 5 out of 5 by from publish usingUsed in WB, got correct MW band at 1:1000 dilution in HeLa whole cell lysates.
Date published: 2017-02-11
Rated 5 out of 5 by from Exceptional immunoperoxidase cytoplasmicExceptional immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human bronchus tissue. -SCBT QC
Date published: 2015-03-15
Rated 5 out of 5 by from Great specificity in WB in HeLaGreat specificity in WB in HeLa, SHP-77 and Hep G2 whole cell lysates. -SCBT QC
Date published: 2015-02-24
Rated 5 out of 5 by from Good clear band seen in WB in Hep G2 wholeGood clear band seen in WB in Hep G2 whole cell lysate. -SCBT QC
Date published: 2015-01-21
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PRX V 抗体 (B-7) is rated 5.0 out of 5 by 7.
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