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Plectin 抗体 (1A2): sc-33650

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说明书
  • Plectin抗体(1A2)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 针对全长胶质瘤C6细胞微丝蛋白(rat来源)
  • 推荐用于 mouse 和 rat 来源的Plectin WB, IP, IF 和 ELISA检测
  • 看 Plectin (10F6): sc-33649,可查看有标记的 Plectin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是Plectin Antibody (1A2) for WB applications. 的首选辅助检测试剂,这些试剂现与Plectin Antibody (1A2) 打包提供(请参阅下面的订购信息)。

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    関連項目

    Plectin是一种丰富的细胞骨架蛋白,参与细胞质稳定。Plectin已被证明可将中间丝交联到微管和微丝上,并将中间丝锚定到质膜和核膜上。Plectin与Lamin B和波形蛋白结合,这种结合受多种蛋白激酶的调节。PKA或PKC的磷酸化导致与Lamin B的结合减少,而PKA的磷酸化增强了plectin-vimentin的相互作用。Plectin也是p34cdc2激酶的底物。已知存在plectin的几种选择性剪接异构体。已知人类凝血素突变可引起伴肌营养不良的单纯型大疱性表皮松解症(EBS-MD)。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Plectin 抗体 (1A2) 参考文献:

    1. 皮肤、骨骼肌和周围神经中的 Plectin 中间丝伙伴关系。  |  Castañón, MJ., et al. 2013. Histochem Cell Biol. 140: 33-53. PMID: 23748243
    2. 通过 plectin 联网和锚定:中频功能和机械传导的关键。  |  Wiche, G., et al. 2015. Curr Opin Cell Biol. 32: 21-9. PMID: 25460778
    3. 关于微管蛋白、plectin、desmin 和波形蛋白在调节肌肉细胞线粒体能量通量中的作用。  |  Mado, K., et al. 2019. Am J Physiol Cell Physiol. 316: C657-C667. PMID: 30811221
    4. Plectin 是前列腺癌生长和转移的调节因子。  |  Buckup, M., et al. 2021. Oncogene. 40: 663-676. PMID: 33219316
    5. Plectin 可确保肠道上皮的完整性,保护结肠免受结肠炎的侵袭。  |  Krausova, A., et al. 2021. Mucosal Immunol. 14: 691-702. PMID: 33674761
    6. 中枢神经系统中的 Plectin 及其在脑星形胶质细胞中的假定作用  |  Potokar, M. and Jorgačevski, J. 2021. Cells. 10: PMID: 34572001
    7. Plectin 介导的细胞骨架串联控制着上皮细胞片的细胞张力和内聚力。  |  Prechova, M., et al. 2022. J Cell Biol. 221: PMID: 35139142
    8. 下调 Plectin 可抑制迁移并通过 ERK1/2 信号抑制肝细胞癌细胞的上皮间质转化体。  |  Xu, R., et al. 2022. Int J Mol Sci. 24: PMID: 36613521
    9. 受机械刺激的埃默里-德赖福斯肌肉萎缩症肌母细胞失去了向细胞核招募 Desmin 和 Plectin 的能力以及细胞核定向能力。  |  Cenni, V., et al. 2024. Cells. 13: PMID: 38247853
    10. Plectin 在星形胶质细胞的迁移和体积调节中发挥作用:胶质母细胞瘤的潜在生物标志物。  |  Žugec, M., et al. 2024. J Biomed Sci. 31: 14. PMID: 38263015

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Plectin 抗体 (1A2)

    sc-33650
    200 µg/ml
    RMB2377.00

    Plectin (1A2): m-IgG Fc BP-HRP 套装

    sc-538928
    200 µg Ab; 10 µg BP
    RMB2662.00

    Plectin (1A2): m-IgG1 BP-HRP 套装

    sc-541158
    200 µg Ab; 20 µg BP
    RMB2662.00

    What is the recommended starting dilution for Western blot for Plectin (1A2): sc-33650 monoclonal antibody?

    Asked by: Cweed
    Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-33650.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Band detected at expected mw in rat brainBand detected at expected mw in rat brain tissue extract. -SCBT QC
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    Plectin 抗体 (1A2) is rated 5.0 out of 5 by 1.
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