Date published: 2025-9-6

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PKC epsilon 抗体 (E-5): sc-1681

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说明书
  • PKC epsilon 抗体 E-5 是小鼠单克隆 IgG1 κ,PKC epsilon抗体, 在48篇文献中引用,规格为200 µg/ml
  • 特定于原点 human 的 723-737 氨基酸之间的表位映射,位于 C-terminus 的 PKC ε(与相应的鼠序列相同)
  • PKC epsilon 抗体 (E-5) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 PKC ε; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • 抗PKC epsilon抗体(E-5)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取PKC epsilon (E-5): sc-1681免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 PKC epsilon 抗体 (E-5) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与PKC epsilon 抗体 (E-5) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

PKC ε 抗体 (E-5) 是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过蛋白质印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、免疫组织化学和酶联免疫吸附测定 (ELISA) 检测小鼠、大鼠和人源的 PKC ε 蛋白。PKC ε 抗体(E-5)有非结合型和多种结合型可供选择,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种 Alexa Fluor® 结合物。PKC epsilon蛋白在细胞信号传导通路中发挥着关键作用,特别是在细胞生长、分化及存活的调节中。PKC epsilon蛋白主要位于细胞质中,激活后可转移到细胞膜上,这对于介导生长因子和激素的反应至关重要。这种转移使PKC epsilon蛋白能够与各种底物和信号分子相互作用,从而影响细胞凋亡和炎症等过程。PKC epsilon蛋白参与基因表达的调节,与多种疾病有关,包括癌症和神经退行性疾病,因此PKC epsilon蛋白成为治疗干预的重要靶点。二酰基甘油和苯氧乙酸酯的特异性激活进一步强调了PKC epsilon蛋白在细胞信号传导中的重要性,以及作为疾病状态生物标志物的潜力。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PKC epsilon 抗体 (E-5) 参考文献:

  1. 蛋白激酶 C 家族的新成员 nPKC theta 主要在骨骼肌中表达。  |  Osada, S., et al. 1992. Mol Cell Biol. 12: 3930-8. PMID: 1508194
  2. 信号转导蛋白激酶家族(蛋白激酶 C 家族)的结构和功能多样性;两类不同的 PKC,即传统的 cPKC 和新型的 nPKC。  |  Ohno, S., et al. 1991. Adv Enzyme Regul. 31: 287-303. PMID: 1877391
  3. 蛋白激酶 C-delta 的表达和特征。  |  Olivier, AR. and Parker, PJ. 1991. Eur J Biochem. 200: 805-10. PMID: 1915352
  4. HASF是一种具有保护心肌细胞新功能的PKC-ε激活剂。  |  Miura, T. 2014. J Mol Cell Cardiol. 69: 1-3. PMID: 24486196
  5. 解构PKC Epsilon在葡萄糖稳态中的作用。  |  Schmitz-Peiffer, C. 2020. Trends Endocrinol Metab. 31: 344-356. PMID: 32305097
  6. PKC-δ和PKC-ε在心肌缺血/再灌注损伤中的作用。  |  Chen, L., et al. 2021. Pharmacol Res. 170: 105716. PMID: 34102229
  7. PKC-ε 可调节囊泡输送和病灶外渗,从而实现高效的 IgG 介导的吞噬作用。  |  D'Amico, AE., et al. 2021. J Cell Sci. 134: PMID: 34622926
  8. 膜磷脂对多功能蛋白激酶的钙依赖性激活。  |  Takai, Y., et al. 1979. J Biol Chem. 254: 3692-5. PMID: 438153
  9. 肌醇磷脂的周转和信号转导  |  Nishizuka, Y. 1984. Science. 225: 1365-70. PMID: 6147898
  10. 蛋白激酶 C 在细胞表面信号转导和肿瘤促进中的作用。  |  Nishizuka, Y. Nature. 308: 693-8. PMID: 6232463
  11. 蛋白激酶 C 可能是促进肿瘤生长的植物醇酯的受体蛋白。  |  Kikkawa, U., et al. 1983. J Biol Chem. 258: 11442-5. PMID: 6311812
  12. 促进肿瘤生长的植物醇酯直接激活钙激活的磷脂依赖性蛋白激酶。  |  Castagna, M., et al. 1982. J Biol Chem. 257: 7847-51. PMID: 7085651

订购信息

产品名称产品编号规格价格数量收藏夹

PKC epsilon 抗体 (E-5)

sc-1681
200 µg/ml
RMB2377.00

PKC epsilon (E-5): m-IgG Fc BP-HRP 套装

sc-528134
200 µg Ab; 10 µg BP
RMB2662.00

PKC epsilon (E-5): m-IgGκ BP-HRP 套装

sc-520438
200 µg Ab, 40 µg BP
RMB2662.00

PKC epsilon (E-5): m-IgG1 BP-HRP 套装

sc-542780
200 µg Ab; 20 µg BP
RMB2662.00

PKC epsilon 抗体 (E-5) AC

sc-1681 AC
500 µg/ml, 25% agarose
RMB3129.00

PKC epsilon 抗体 (E-5) HRP

sc-1681 HRP
200 µg/ml
RMB2377.00

PKC epsilon 抗体 (E-5) FITC

sc-1681 FITC
200 µg/ml
RMB2482.00

PKC epsilon 抗体 (E-5) PE

sc-1681 PE
200 µg/ml
RMB2580.00

PKC epsilon 抗体 (E-5) Alexa Fluor® 488

sc-1681 AF488
200 µg/ml
RMB2685.00

PKC epsilon 抗体 (E-5) Alexa Fluor® 546

sc-1681 AF546
200 µg/ml
RMB2685.00

PKC epsilon 抗体 (E-5) Alexa Fluor® 594

sc-1681 AF594
200 µg/ml
RMB2685.00

PKC epsilon 抗体 (E-5) Alexa Fluor® 647

sc-1681 AF647
200 µg/ml
RMB2685.00

PKC epsilon 抗体 (E-5) Alexa Fluor® 680

sc-1681 AF680
200 µg/ml
RMB2685.00

PKC epsilon 抗体 (E-5) Alexa Fluor® 790

sc-1681 AF790
200 µg/ml
RMB2685.00

PKC epsilon (E-5) 中和勝肽

sc-1681 P
100 µg/0.5 ml
RMB511.00

I need to use an antibody to detect the protein in samples of porcine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: cjMara
Yes. PKC ε (E-5): sc-1681 monoclonal antibody is recommended for use in porcine samples. It is also recommended for use in mouse, rat, human, equine, canine and bovine samples.
Answered by: Technical Support 9
Date published: 2019-04-26
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Rated 5 out of 5 by from great antibodyAntibody works perfekt in rat liver samples, dilution 1:1000
Date published: 2018-09-05
Rated 3 out of 5 by from I got a faint bandI tested this antibody in Jan 2018. I used 1:200 dilution and got a faint band.
Date published: 2018-02-13
Rated 5 out of 5 by from This antibody works wellPKC ε antibody with a precise position effect and very powerful signal in rat brain tissue extracts when we diluted with 1:1000.
Date published: 2017-10-22
Rated 4 out of 5 by from I used 1:200 in MEF for WB, I have got a clean banI used 1:200 in MEF for WB, I have got a band, but it was not very clear.
Date published: 2017-09-14
Rated 5 out of 5 by from loading 5oug sampleUse this antibody detect human breast cancer cell MCF-7, the loading amount is 50ug, I suggest use it as positive sample, and diluted the antibody at 1:800 for WB.
Date published: 2017-06-25
Rated 5 out of 5 by from A satisfactory antibodyWe used this antibody WB to dilute 1:500 in mouse cells best
Date published: 2017-05-25
Rated 3 out of 5 by from Human PBMNI tested this antibody by western blot by using human peripheral blood mononuclear cell (PBMC). I was unable to pick up any band in human PBMC.
Date published: 2017-05-22
Rated 5 out of 5 by from Great antibody for flow cytometryThis antibody worked well for flow cytometry using SupT1 cells
Date published: 2017-03-07
  • y_2025, m_8, d_30, h_9
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PKC epsilon 抗体 (E-5) is rated 4.7 out of 5 by 16.
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