Date published: 2025-10-24

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OMP 抗体 (B-6): sc-365818

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说明书
  • OMP 抗体 B-6 是小鼠单克隆 IgG2a κ,OMP抗体, 在16篇文献中引用,规格为200 µg/ml
  • 免疫human物种的代表全长OMP的氨基酸1-163
  • OMP 抗体 (B-6) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 OMP
  • 抗OMP抗体(B-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 目前,我们还没有完成OMP 抗体 (B-6)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

OMP抗体(B-6)是一种IgG2a κ型小鼠单克隆OMP抗体(也称为OMP抗体),可通过WB、IP、IF、IHC(P)和ELISA技术检测小鼠、大鼠和人类来源的OMP蛋白。OMP抗体(B-6)既可以是非偶联的抗OMP抗体形式,也可以是多种偶联形式的抗OMP抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。嗅觉标记蛋白(OMP)已被证明与大脑中表达的X连锁基因Bex1和Bex2相互作用。它在鼻腔神经上皮的嗅觉化学感受神经元的细胞质中表达。OMP表达是成熟脊椎动物嗅觉受体神经元(ORNs)的标志。OMP RNA在上皮中的神经细胞体内合成,然后被转运到嗅觉球中的轴突和末端进行翻译。OMP可能在气味检测/信号转导级联反应中具有调节作用。在胎儿嗅觉上皮细胞中,OMP也是强有力的有丝分裂增强剂,并促进肝脏对氚标记的胸腺嘧啶的吸收增加。OMP基因的缺失会导致对气味刺激的反应能力受损,并提高行为阈值敏感性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

OMP 抗体 (B-6) 参考文献:

  1. TGF-α 和嗅标记蛋白可促进体内大鼠嗅上皮细胞的有丝分裂。  |  Farbman, AI. and Ezeh, PI. 2000. Neuroreport. 11: 3655-8. PMID: 11095538
  2. 鉴定作为嗅觉标记蛋白(OMP)结合伙伴的 Bex 基因家族成员。  |  Behrens, M., et al. 2003. J Neurochem. 86: 1289-96. PMID: 12911636
  3. 在没有嗅球的情况下,表达 Bcl-2 可延长嗅觉受体神经元的存活时间。  |  Hayward, MD., et al. 2004. Brain Res Mol Brain Res. 132: 221-34. PMID: 15582160
  4. 通过与附属嗅球神经元共培养使体外绒毛膜受体神经元成熟  |  Moriya-Ito, K., et al. 2005. Chem Senses. 30: 111-9. PMID: 15703330
  5. 载脂蛋白E缺陷小鼠的嗅神经再生延迟  |  Nathan, BP., et al. 2005. Brain Res. 1041: 87-94. PMID: 15804503
  6. 鼻窦闭塞会改变嗅上皮的嗅标记蛋白免疫反应。  |  Waguespack, AM., et al. 2005. Brain Res. 1044: 1-7. PMID: 15862783
  7. 嗅觉标记蛋白调节嗅球中初级嗅觉轴突的过度运动  |  St John, JA. and Key, B. 2005. J Comp Neurol. 488: 61-9. PMID: 15912500
  8. 通过 15N NMR 驰豫测量研究嗅觉标记蛋白的骨架动态。  |  Gitti, RK., et al. 2005. Biochemistry. 44: 9673-9. PMID: 16008352
  9. 靶向人类癌症中的Wnt通路:以OMP-54F28为重点的治疗靶向。  |  Le, PN., et al. 2015. Pharmacol Ther. 146: 1-11. PMID: 25172549
  10. 基因表达数据中特征选择的γ-OMP算法。  |  Tsagris, M., et al. 2022. IEEE/ACM Trans Comput Biol Bioinform. 19: 1214-1224. PMID: 33035156
  11. OMP-52 M51的抗NOTCH1疗法通过抑制上皮-间质转化(EMT)过程和诱导铁死亡来抑制唾液腺腺样囊性癌。  |  Li, R., et al. 2024. Toxicol Appl Pharmacol. 484: 116825. PMID: 38253083
  12. 嗅觉标记蛋白(OMP)。  |  Margolis, FL. 1982. Scand J Immunol Suppl. 9: 181-99. PMID: 6963760
  13. 嗅觉标记蛋白(OMP)基因缺失会导致嗅觉神经元的生理活动发生改变。  |  Buiakova, OI., et al. 1996. Proc Natl Acad Sci U S A. 93: 9858-63. PMID: 8790421

订购信息

产品名称产品编号规格价格数量收藏夹

OMP 抗体 (B-6)

sc-365818
200 µg/ml
RMB2377.00

OMP 抗体 (B-6) AC

sc-365818 AC
500 µg/ml, 25% agarose
RMB3129.00

OMP 抗体 (B-6) HRP

sc-365818 HRP
200 µg/ml
RMB2377.00

OMP 抗体 (B-6) FITC

sc-365818 FITC
200 µg/ml
RMB2482.00

OMP 抗体 (B-6) PE

sc-365818 PE
200 µg/ml
RMB2580.00

OMP 抗体 (B-6) Alexa Fluor® 488

sc-365818 AF488
200 µg/ml
RMB2685.00

OMP 抗体 (B-6) Alexa Fluor® 546

sc-365818 AF546
200 µg/ml
RMB2685.00

OMP 抗体 (B-6) Alexa Fluor® 594

sc-365818 AF594
200 µg/ml
RMB2685.00

OMP 抗体 (B-6) Alexa Fluor® 647

sc-365818 AF647
200 µg/ml
RMB2685.00

OMP 抗体 (B-6) Alexa Fluor® 680

sc-365818 AF680
200 µg/ml
RMB2685.00

OMP 抗体 (B-6) Alexa Fluor® 790

sc-365818 AF790
200 µg/ml
RMB2685.00

gegen welche Aminosäuren von OMP ist dieser Antikörper gerichtet? Wir würden gerne einen Sandwich ELISA für OMP etablieren und benötigen daher zwei kompatible Antikörper mit verschiedenen Epitopen am OMP Protein.

Asked by: Meix
Vielen Dank für Ihre Frage. OMP Antikörper (B-6): sc-365818 ist spezifisch gegen die Aminosäuresequenz 1-163 entsprechend dem Volllängeprotein OMP aus der Spezies human. Das exakte Epitop dieses Antikörpers wurde bisher nicht bestimmt. Thank you for your question. OMP antibody (B-6): sc-365818 is specific against the amino acid sequence 1-163 corresponding to the full-length OMP protein from the human species. Epitope mapping has not yet been performed for this antibody.
Answered by: Tech Support Europe
Date published: 2025-10-10

I am using OMP (B-6): sc-365818 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Randy McDonald
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2023-08-07
  • y_2025, m_10, d_24, h_8CST
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Rated 5 out of 5 by from Good antibodyThe antibody works well for the immunostaining of mouse olfactory bulb and mouse olfactory epithelium cells.
Date published: 2021-11-05
Rated 5 out of 5 by from Excellent!This antibody works great in immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
Date published: 2017-01-20
Rated 5 out of 5 by from Received as a replacement and is working very wellReceived as a replacement and is working very well.
Date published: 2015-09-22
Rated 5 out of 5 by from Superb immunofluorescence cytoplasmic stainingSuperb immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-02-11
Rated 5 out of 5 by from Great Western Blot data of OMP expression in nonGreat Western Blot data of OMP expression in non-transfected and mouse OMP transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-03-27
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OMP 抗体 (B-6) is rated 5.0 out of 5 by 5.
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