Date published: 2025-9-8

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Notch 4 抗体 (C-3): sc-377399

5.0(2)
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说明书
  • Notch 4抗体(C-3)是小鼠单克隆IgG3 κ, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于mouse物种的Notch 4的N-terminus附近的氨基酸3-31之间
  • 推荐用于 mouse 和 rat 来源的Notch 4 WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 Notch 4 (A-12): sc-393893,可查看有标记的 Notch 4 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Notch 4 抗体 (C-3)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

LIN-12/Notch跨膜受体被认为在通过调节细胞命运决定在发育中起核心作用。在哺乳动物中已经发现了四种Notch同源物(Notch 1、Notch 2、Notch 3和Notch 4)。Notch基因在多种胚胎和成人组织中表达,表明这些基因参与多种信号通路。已发现Notch蛋白在人类肿瘤中过度表达或重排。Notch的配体包括Jagged1、Jagged2和Delta。Jagged1可以通过抑制肌肉调节和结构基因的表达来激活Notch并阻止成肌细胞分化。Jagged2可能参与依赖于上皮-间充质相互作用的组织发育。除了其在肾上腺和胎盘中的正常表达外,还在神经内分泌肿瘤中发现了Delta的表达。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Notch 4 抗体 (C-3)

sc-377399
200 µg/ml
RMB2377.00

Notch 4 (C-3) 中和勝肽

sc-377399 P
100 µg/0.5 ml
RMB511.00

According to this datasheet, this NOTCH4 antibody (C3; sc-377399) is suitable for mouse or rat IHC. I'd like to ask you whether you've already tried this antibody for the human tissue IHC. If so, could you teach me the results for human?

Asked by: KIYOSHI
Thank you for your question. We have not yet confirmed reactivity of this specific Notch 4 antibody with human samples, and so it is not a recommended species reactivity for this clone at this time. This clone is specifically recommended for mouse and rat Notch 4. We do have a different Notch 4 antibody that is recommended for human, Notch 4 Antibody (A-12): sc-393893. However, this antibody has not yet been tested for IHC(P), or IHC on FFPE.
Answered by: Technical Support
Date published: 2020-02-19

What application is the blocking peptide sc-377399 P appropriate for?

Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from CleanClean, robust band observed when used for immunoblotting mouse kidney tissue extracts. -SCBT QC
Date published: 2015-05-18
Rated 5 out of 5 by from Exceptional immunofluorescence cytoplasmicExceptional immunofluorescence cytoplasmic staining in methanol-fixed NIH/3T3 cells. -SCBT QC
Date published: 2015-04-20
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Notch 4 抗体 (C-3) is rated 5.0 out of 5 by 2.
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