Date published: 2026-10-24

1-800-457-3801

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
NGFR p75 Antibody (5H1) - Western Blotting - Image 377271
NGFR p75 抗体 (5H1): sc-71693. Neuro-2A (A), F9 (B), NIH/3T3 (C), U-87 MG (D) 和 PC-3 (E) 全细胞裂解液中 NGFR p75 表达的 Western 印迹分析.
NGFR p75 抗体 (5H1): sc-71693. Neuro-2A (A), F9 (B), NIH/3T3 (C), U-87 MG (D) 和 PC-3 (E) 全细胞裂解液中 NGFR p75 表达的 Western 印迹分析.

NGFR p75 抗体 (5H1): sc-71693

4.3(3)
寫評論提問
说明书
  • NGFR p75抗体(5H1)是小鼠单克隆IgG1 κ, 在2篇文献中引用，规格为200 µg/ml
  • 针对human来源的WM245黑色素瘤细胞
  • 推荐用于 mouse, rat 和 human 来源的NGFR p75 WB, IP, IF 和 IHC(P)检测; 也和以下物种反应，包括： 和 bovine, porcine, feline and canine
  • 看 NGFR p75 (B-1): sc-271708，可查看有标记的 NGFR p75 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 1 BP-HRP">m-IgG1 BP-HRP是NGFR p75 Antibody (5H1) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现与NGFR p75 Antibody (5H1) 打包提供（请参阅下面的订购信息）。
Gene Editing Promo Banner

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

Trk 癌基因编码跨膜蛋白酪氨酸激酶 gp140Trk，其表达在体内仅限于神经嵴起源的感觉脊髓和颅神经节的神经元。神经生长因子 (NGF) 刺激神经细胞系和胚胎背根神经节中 Trk A 的酪氨酸磷酸化。 NGF 对 Trk A 的酪氨酸磷酸化是快速、特异性的，并且以皮摩尔数量的因子发生，表明该反应是由生理量的 NGF 介导的，表明 Trk A 参与 NGF 的主要信号转导机制。 Trk A 受体复合物的另一个组分 NGFR p75 以低亲和力与神经营养因子结合，但有效信号传导是必需的。 NGFR p75 加速 Trk A 激活，并可能招募下游效应分子到结合复合物。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

NGFR p75 抗体 (5H1) 参考文献:

  1. p75 神经营养素受体相互作用因子 TRAF6 和 NRIF 之间的功能性相互作用。  |  Gentry, JJ., et al. 2004. J Biol Chem. 279: 16646-56. PMID: 14960584
  2. 截短的TrkB受体诱导的树突状纤毛突生长涉及p75神经生长因子受体。  |  Hartmann, M., et al. 2004. J Cell Sci. 117: 5803-14. PMID: 15507485
  3. p75神经生长因子受体减少配体诱导的Trk受体泛素化，并延迟Trk受体的内化和降解。  |  Makkerh, JP., et al. 2005. EMBO Rep. 6: 936-41. PMID: 16113645
  4. p75神经营养因子受体介导的信号传导促进人类毛囊退化（生长期）。  |  Peters, EM., et al. 2006. Am J Pathol. 168: 221-34. PMID: 16400025
  5. p75神经营养因子受体的表达定义了BDNF反应性神经前体细胞群。  |  Young, KM., et al. 2007. J Neurosci. 27: 5146-55. PMID: 17494700
  6. 在成年大鼠的黑质多巴胺神经元中鉴定和卡因酸诱导的低亲和力p75神经生长因子受体（p75NTR）上调。  |  Wang, YQ., et al. 2008. Neurochem Int. 53: 56-62. PMID: 18639597
  7. p75神经营养因子受体调节海马神经发生和相关行为。  |  Catts, VS., et al. 2008. Eur J Neurosci. 28: 883-92. PMID: 18717734
  8. 通过p75神经营养因子受体对神经营养因子信号传导进行遗传学剖析。  |  Charalampopoulos, I., et al. 2012. Cell Rep. 2: 1563-70. PMID: 23260665
  9. p75神经营养因子受体中死亡域信号传导的结构基础。  |  Lin, Z., et al. 2015. Elife. 4: e11692. PMID: 26646181
  10. 沉默p75NTR可调节BMSC的成骨分化与血管生成，从而促进骨折大鼠的骨愈合。  |  Wu, Z., et al. 2024. J Orthop Surg Res. 19: 192. PMID: 38504358

订购信息

产品名称产品编号规格价格数量收藏夹

NGFR p75 抗体 (5H1)

sc-71693
200 µg/ml
CNY2422.00

NGFR p75 (5H1): m-IgG1 BP-HRP 套装

sc-542618
200 µg Ab; 20 µg BP
CNY2715.00

p75NTR usually runs around 75 kDa with the post-translational modifications but on the 20 samples I had, it ended up running around 95 to 100 kDa. Does anyone knows why?

Asked by: SammyBoi
Thank you for your question. Please contact our Technical Service Department for assistance in troubleshooting this antibody.
Answered by: Technical Support
Date published: 2019-06-15

How much sample do you recommend loading on the gel for Western blot detection using NGFR p75 (5H1): sc-71693?

Asked by: Dr Ninau Qelp
We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-01
  • y_2026, m_10, d_23, h_6CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_71693, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 90ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by ET from Published data in uterine tissue using thisPublished data in uterine tissue using this antibody for Western blot analysis -SCBT Publication Review
Date published: 2015-06-19
Rated 4 out of 5 by HC from Good signal using this antibody against SKGood signal using this antibody against SK-N-MC whole cell lysate in WB. -SCBT QC
Date published: 2015-03-30
Rated 4 out of 5 by ET from IHC(P) publishable data with human uterine tissueIHC(P) publishable data with human uterine tissue - SCBT Publication Review
Date published: 2015-03-26
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_71693, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT
NGFR p75 抗体 (5H1) is rated 4.3 out of 5 by 3.
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_71693, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 101ms
  • REVIEWS, PRODUCT
1-800-457-3801
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打1-800-457-3801联系我们。
版权所有© 2007-2026 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。