Date published: 2025-9-7

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Mucin 2/MUC2 抗体 (B306.1): sc-59859

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说明书
  • Mucin 2/MUC2抗体(B306.1)是小鼠单克隆IgG1 κ, 在15篇文献中引用,规格为200 µg/ml
  • 针对human来源的合成Mucin 2
  • 推荐用于 mouse, rat 和 human 来源的Mucin 2 IF 和 IHC(P)检测
  • 看 Mucin 2/MUC2 (F-2): sc-515032,可查看有标记的 Mucin 2/MUC2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是Mucin 2/MUC2 Antibody (B306.1) for IHC(P) applications. 的首选辅助检测试剂,这些试剂现与Mucin 2/MUC2 Antibody (B306.1) 打包提供(请参阅下面的订购信息)。

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粘蛋白是一个高度糖基化的分泌蛋白家族,其基本结构由60个碱基对(粘蛋白1)、69个碱基对(粘蛋白2)和51个碱基对(粘蛋白3)编码的可变数量的串联重复序列(VNTR)组成。重复次数具有高度多态性,并且在不同的等位基因之间存在差异。粘蛋白1蛋白质除了分泌形式外,还以I型膜蛋白的形式表达。粘蛋白1在包括乳腺癌在内的上皮肿瘤中异常表达。粘蛋白2覆盖肠道和气道上皮细胞,并与结肠肿瘤有关。粘蛋白3是各种粘液凝胶的主要成分,在正常和肿瘤细胞中广泛表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Mucin 2/MUC2 抗体 (B306.1) 参考文献:

  1. 肠道粘蛋白-2的缺乏可保护小鼠免受饮食诱导的脂肪肝和肥胖。  |  Hartmann, P., et al. 2016. Am J Physiol Gastrointest Liver Physiol. 310: G310-22. PMID: 26702135
  2. 粘蛋白2沉默通过白细胞介素6信号传导促进结肠癌转移。  |  Hsu, HP., et al. 2017. Sci Rep. 7: 5823. PMID: 28725043
  3. 慢性应激通过扰乱肠道菌群和触发免疫系统反应来促进结肠炎。  |  Gao, X., et al. 2018. Proc Natl Acad Sci U S A. 115: E2960-E2969. PMID: 29531080
  4. 乳腺癌患者血清膜结合黏蛋白-2水平的临床意义。  |  Bademler, S., et al. 2019. Biomolecules. 9: PMID: 30682816
  5. 粘蛋白 2 及其与硫醇化壳聚糖相互作用的计算研究:粘液粘附和药物保留的新见解。  |  Cavalcanti da Silveira, CO., et al. 2020. J Biomol Struct Dyn. 38: 1479-1487. PMID: 31014188
  6. 粘蛋白-2基因敲除是肠道上皮细胞间连接缺陷、线粒体损伤和ATP耗竭的模型。  |  Borisova, MA., et al. 2020. Sci Rep. 10: 21135. PMID: 33273633
  7. 地中海式脂肪混合物可防止黏蛋白-2缺乏小鼠模型出现严重结肠炎。  |  Haskey, N., et al. 2022. Gut Microbes. 14: 2055441. PMID: 35471119
  8. 影响结直肠癌切除患者粘蛋白1、粘蛋白2和粘蛋白5AC染色的临床病理因素。  |  Anuk, T., et al. 2023. J Coll Physicians Surg Pak. 33: 335-340. PMID: 36945166
  9. 粘蛋白-微生物组特征塑造胃癌的肿瘤微环境。  |  Oosterlinck, B., et al. 2023. Microbiome. 11: 86. PMID: 37085819
  10. 粘蛋白2的低表达、粘蛋白13的高表达以及核因子Kappa-Light-Enhancer of Activated B细胞的高表达是结直肠癌发展的显著途径。  |  Mulyawan, IM. 2023. Asian Pac J Cancer Prev. 24: 1119-1123. PMID: 37116131

订购信息

产品名称产品编号规格价格数量收藏夹

Mucin 2/MUC2 抗体 (B306.1)

sc-59859
200 µg/ml
$316.00

Mucin 2/MUC2 (B306.1): m-IgG Fc BP-HRP 套装

sc-539144
200 µg Ab; 10 µg BP
$354.00

Mucin 2/MUC2 (B306.1): m-IgG1 BP-HRP 套装

sc-541291
200 µg Ab; 20 µg BP
$354.00

Hi - I am deparaffinizing fixed intestinal slices and hybridizing w/ 16S RNA-FISH probe. Will the muc2 Ab be compatible with other stains @ end of the protocol, i.e. Dapi/Phalloidin? Mucin 2/MUC2 ab (B306.1): sc-598 Best,

Asked by: eeb8hh
Thank you for your question. For assistance please contact technical service. (800)-457-3801 or [email protected]
Answered by: BlakeJ
Date published: 2023-04-19

I need to use an antibody to detect the protein in samples of monkey origin. Do you know if sc-59859: Mucin 2 (B306.1) mouse monoclonal antibody will work?

Asked by: Professor Griffin
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2018-09-29

Bonjour, Auriez-vous l'exemple d'un résultat de western-blot ayant fonctionné contre une Mucin2 (mouse) ? J'ai déja un anticorps santa cruz anti mucin2 mais celui ci ne fonctionne qu'en IF. Je cherche celui qui me permettra de la détecter en WB.

Asked by: Matthias
Merci pour votre question. L'anticorps Mucin 2 (B306.1): sc-59859 est recommandé pour la détection de Mucin 2 de souris, rat et humaine par les techniques de Western Blot, IF and IHC(P). Nous n'avons malheureusement pas d'image de résultats en Western Blot pour cet anticorps. (PMID: 21278735 pour la détection de Mucin 2 de souris). Cependant, nous offrons une garantie valable pendant un an à partir de la date d'achats pour les applications et espèces recommandées. Ainsi, si vous rencontrez des difficultés avec cet anticorps et que celui-ci ne devait pas fonctionner suivant nos recommandations, veuillez nous contacter par téléphone +49 6221 45 030 ou par email à [email protected]. -- Thank you for your question. The antibody Mucin 2 (B306.1): sc-59859 is recommended for detection of Mucin 2 of mouse, rat and human origin by WB, IF and IHC(P). We currently do not have a picture available for this antibody in Western Blot. However, we offer a product warranty of one year from the date of purchase for the recommended applications and species. Therefore, if you are experiencing some issues with this antibody, please contact us by phone +49 6221 45 030 or by email at [email protected]. We also list one citation for the use of this antibody on mouse samples: PMID: 21278735
Answered by: Technical Support Europe
Date published: 2024-04-30
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Rated 5 out of 5 by from Popular antibodyThis is a very popular antibody for Mucin 2 detection!
Date published: 2017-02-06
Rated 4 out of 5 by from Good staining in paraffinGood staining in paraffin-embedded mouse intestine in IHC -SCBT Publication Review
Date published: 2014-07-20
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Mucin 2/MUC2 抗体 (B306.1) is rated 4.5 out of 5 by 2.
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