Date published: 2025-9-8
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MRP2 抗体 (M2 III-6): sc-59608

4.8(4)
寫評論提問

说明书
  • MRP2 抗体 M2 III-6 是小鼠单克隆 IgG2a, 在10篇文献中引用，提供 50 µg/0.5 ml
  • 与human起源的MRP2的C-terminal区域
  • 推荐用于 human 来源的MRP2 WB, IF 和 IHC(P)检测; 不会与 human MDR 1, MRP 1, MRP 3 or MRP 5 gene products产生交联反应
  • 目前，我们还没有完成MRP2 抗体 (M2 III-6)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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基因信息
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研究信息

関連項目

额外MRP抗体，包括MRP1, MRP2, MRP3, MRP4, MRP5和MRP6

MRP2抗体（M2 III-6）是一种小鼠单克隆IgG2a抗体，可通过蛋白质印迹（WB）、免疫荧光（IF）和石蜡包埋切片免疫组织化学（IHCP）检测人类来源的MRP2。抗MRP2抗体（M2 III-6）以非结合形式提供，可在研究中广泛使用。MRP2也称为管状多特异性有机阴离子转运体（cMOAT），在将各种有机阴离子和药物从肝细胞排泄到胆汁的过程中发挥着关键作用，从而促进肝脏的解毒过程。MRP2主要定位于肝细胞的顶端膜，在该处高表达对于维持正常的胆汁流动和防止潜在有害物质积聚至关重要。MRP2的功能在药物代谢和耐药性方面尤为重要，因为它有助于调节体内治疗药物及其代谢产物的水平。MRP2失调或受损可导致严重的临床后果，包括药物性肝损伤和各种药物的药代动力学改变。了解MRP2的表达和功能对于制定克服癌症治疗中多药耐药性的策略和优化药物输送系统至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

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产品名称产品编号规格价格数量收藏夹

MRP2 抗体 (M2 III-6)

sc-59608
50 µg/0.5 ml
RMB2377.00

Is this antibody reactive with mouse MRP2?

Asked by: AbPolly
Thank you for your question. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Service 11
Date published: 2024-07-19
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Rated 5 out of 5 by from Good for human detection.This antibody will show clear detection of you MRP2 antibody in most lab applications. It has been cited multiple times.
Date published: 2017-01-27
Rated 5 out of 5 by from Very good IF staining of liver cells andVery good IF staining of liver cells and gut epithelium.
Date published: 2016-09-02
Rated 5 out of 5 by from Used for IHC and it's working wellUsed for IHC and it's working well.
Date published: 2015-09-16
Rated 4 out of 5 by from Good publishable data in IHC using human liverGood publishable data in IHC using human liver -SCBT Publication Review
Date published: 2013-10-03
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MRP2 抗体 (M2 III-6) is rated 4.8 out of 5 by 4.
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