Date published: 2025-9-8

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MRP2 抗体 (6D564): sc-71603

4.6(5)
寫評論提問

说明书
  • MRP2 抗体 6D564 是小鼠单克隆 IgG1, 在3篇文献中引用,提供 500 µl supernatant
  • 免疫human物种的MRP2的氨基酸215-310
  • 推荐用于 human 来源的MRP2 WB, IP 和 IF检测; 不会与 MDR1, MRP1, MRP3 or MRP5产生交联反应
  • 目前,我们还没有完成MRP2 抗体 (6D564)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

MRP2抗体(6D564)是一种IgG1小鼠单克隆MRP2抗体,通过WB、IP和IF检测人类来源的MRP2。MRP2抗体可以是非偶联的抗MRP2抗体形式。已知在人类癌症细胞中赋予多药耐药性的ABC转运蛋白大家族的两个成员是Mdr-1 P-糖蛋白和多药耐药蛋白MRP1。MRP1是一种完整的膜蛋白,包含MDR样核心、N端膜结合区和细胞质连接体,在各种脑细胞、肺、睾丸和外周血中表达。MRP基因家族还包括MRP2和MRP3,它们都是主要在肝细胞中表达的缀合物输出泵,MRP2也被命名为cMOAT(用于小管多特异性有机阴离子转运蛋白)。MRP2仅定位于心尖膜,并在正常肝细胞中以高水平组成性表达。相反,MRP3定位于基底外侧膜,在那里它还介导有机阴离子S-(2,4-二硝基苯基-)谷胱甘肽向膜的基底外侧的转运。MRP3通常以相对低于MRP2的水平表达,并且仅当MRP2通过顶膜的分泌受损时才增加。MRP6在肝脏和肾脏中高表达,而MRP4和MRP5在各种组织中检测到,但表达水平要低得多。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

MRP2 抗体 (6D564)

sc-71603
500 µl supernatant
RMB2377.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with MRP2 (6D564): sc-71603 antibody?

Asked by: TinTin
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
  • y_2025, m_8, d_30, h_9CST
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Rated 5 out of 5 by from greatgreat antibody work well in WB at 1:300, bladder cancer
Date published: 2017-07-06
Rated 5 out of 5 by from superbStrong band in WB in A-431 whole cell lysates, I'll continue to use it.
Date published: 2017-03-18
Rated 5 out of 5 by from Strong and clearStrong and clear band produced with MRP2 Antibody (6D564)
Date published: 2017-01-25
Rated 4 out of 5 by from Western blot publication in HepG2Western blot publication in HepG2, SGC7901, HepG2/AS and SGC7901/AS cells. -SCBT Publication Review
Date published: 2015-05-02
Rated 4 out of 5 by from WB: Single strong bands in JAR and AWB: Single strong bands in JAR and A-431 whole cell lysates. -SCBT QC
Date published: 2014-11-14
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MRP2 抗体 (6D564) is rated 4.6 out of 5 by 5.
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