Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

MGMT 抗体 (G-10): sc-514277

5.0(2)
寫評論提問

说明书
  • MGMT 抗体 G-10 是小鼠单克隆 IgG2b,提供 200 µg/ml
  • 特异性抗原位于human物种的MGMT的C-terminus的氨基酸185-207之间
  • 推荐用于 human 来源的MGMT WB, IP, IF 和 ELISA检测
  • 看 MGMT (E-1): sc-166528,可查看有标记的 MGMT 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRP是MGMT Antibody (G-10) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与MGMT Antibody (G-10) 打包提供(请参阅下面的订购信息)。

    快捷链接

    関連項目

    MGMT(O6-甲基鸟嘌呤-DNA甲基转移酶)在DNA损伤时会被转录激活,并起到修复由致癌物或细胞抑制剂引起的致突变和细胞毒性的O6-烷基鸟嘌呤损伤的作用。在p53缺陷型小鼠中,电离辐射不会诱导MGMT的产生,这表明MGMT的诱导可能需要p53的参与。同样地,研究表明,只有在表达功能性p53的细胞系中,MGMT的mRNA和蛋白质才能被电离辐射诱导产生,而在不表达野生型p53的细胞系中则不行。相反,在对口腔癌细胞系的研究中发现,高MGMT活性与突变型p53的存在有关。类似地,与具有突变型p53的肿瘤相比,具有野生型p53的卵巢肿瘤中的MGMT活性显著降低,这支持了野生型p53下调基础MGMT启动子的观点。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    MGMT 抗体 (G-10)

    sc-514277
    200 µg/ml
    RMB2377.00

    MGMT (G-10): m-IgG Fc BP-HRP 套装

    sc-540969
    200 µg Ab; 10 µg BP
    RMB2662.00

    MGMT (G-10): m-IgG2b BP-HRP 套装

    sc-549795
    200 µg Ab; 10 µg BP
    RMB2662.00

    MGMT (G-10) 中和勝肽

    sc-514277 P
    100 µg/0.5 ml
    RMB511.00

    What application is the blocking peptide sc-514277 P appropriate for?

    Asked by: cjMara
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-24
    • y_2025, m_9, d_7, h_4CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_zh_CN, sid_514277, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 125ms
    • QUESTIONS, PRODUCT
    Rated 5 out of 5 by from Great monoclonal antibodyMGMT Antibody (G-10) produced strong positive results by Western blot
    Date published: 2017-02-10
    Rated 5 out of 5 by from Nice Western blot data of MGMT expression in nonNice Western blot data of MGMT expression in non-transfected 293T, human MGMT transfected 293T MCF7, Hep G2 and Caco-2 whole cell lysates. -SCBT QC
    Date published: 2014-06-28
    • y_2025, m_9, d_7, h_4
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_2
    • loc_zh_CN, sid_514277, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 15ms
    • REVIEWS, PRODUCT
    MGMT 抗体 (G-10) is rated 5.0 out of 5 by 2.
    • y_2025, m_9, d_7, h_4
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_2
    • loc_zh_CN, sid_514277, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 102ms
    • REVIEWS, PRODUCT